Chlorine in PDB 8sxd: Campylobacter Jejuni Keto-Acid Reductoisomerase in Complex with Intermediate and Nadp+

Enzymatic activity of Campylobacter Jejuni Keto-Acid Reductoisomerase in Complex with Intermediate and Nadp+

All present enzymatic activity of Campylobacter Jejuni Keto-Acid Reductoisomerase in Complex with Intermediate and Nadp+:
1.1.1.86;

Protein crystallography data

The structure of Campylobacter Jejuni Keto-Acid Reductoisomerase in Complex with Intermediate and Nadp+, PDB code: 8sxd was solved by X.Lin, T.Lonhienne, L.W.Guddat, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 37.74 / 2.59
Space group I 2 3
Cell size a, b, c (Å), α, β, γ (°) 130.72, 130.72, 130.72, 90, 90, 90
R / Rfree (%) 19.1 / 24.5

Other elements in 8sxd:

The structure of Campylobacter Jejuni Keto-Acid Reductoisomerase in Complex with Intermediate and Nadp+ also contains other interesting chemical elements:

Magnesium (Mg) 2 atoms

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Campylobacter Jejuni Keto-Acid Reductoisomerase in Complex with Intermediate and Nadp+ (pdb code 8sxd). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Campylobacter Jejuni Keto-Acid Reductoisomerase in Complex with Intermediate and Nadp+, PDB code: 8sxd:

Chlorine binding site 1 out of 1 in 8sxd

Go back to Chlorine Binding Sites List in 8sxd
Chlorine binding site 1 out of 1 in the Campylobacter Jejuni Keto-Acid Reductoisomerase in Complex with Intermediate and Nadp+


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Campylobacter Jejuni Keto-Acid Reductoisomerase in Complex with Intermediate and Nadp+ within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl406

b:147.4
occ:0.33
NH2 A:ARG297 3.1 106.4 1.0
CZ A:ARG297 3.4 99.7 1.0
NE A:ARG297 3.8 97.7 1.0
NH1 A:ARG297 3.9 94.0 1.0
CB A:ARG297 4.1 80.1 1.0
CG A:ARG297 4.6 82.3 1.0
CD A:ARG297 4.7 84.7 1.0

Reference:

X.Lin, T.Lonhienne, Y.Lv, J.Kurz, R.Mcgeary, G.Schenk, L.W.Guddat. Mapping of the Reaction Trajectory Catalyzed By Class I Ketol-Acid Reductoisomerase Acs Catalysis 2024.
ISSN: ESSN 2155-5435
DOI: 10.1021/ACSCATAL.4C00958
Page generated: Tue Jul 30 12:39:10 2024

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