Chlorine in PDB 8t52: Hiv-1 Integrase Catalytic Core Domain (Ccd) F185H/Y99H/A128T Mutant Complexed with Ekc-110

The structure of Hiv-1 Integrase Catalytic Core Domain (Ccd) F185H/Y99H/A128T Mutant Complexed with Ekc-110, PDB code: 8t52 was solved by T.Dinh, M.Kvaratskhelia, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	31.73 / 2.07
Space group	P 31 2 1
Cell size a, b, c (Å), α, β, γ (°)	72.243, 72.243, 66.423, 90, 90, 120
R / Rfree (%)	26.4 / 31.4

The binding sites of Chlorine atom in the Hiv-1 Integrase Catalytic Core Domain (Ccd) F185H/Y99H/A128T Mutant Complexed with Ekc-110 (pdb code 8t52). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Hiv-1 Integrase Catalytic Core Domain (Ccd) F185H/Y99H/A128T Mutant Complexed with Ekc-110, PDB code: 8t52:

Chlorine binding site 1 out of 1 in the Hiv-1 Integrase Catalytic Core Domain (Ccd) F185H/Y99H/A128T Mutant Complexed with Ekc-110


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Hiv-1 Integrase Catalytic Core Domain (Ccd) F185H/Y99H/A128T Mutant Complexed with Ekc-110 within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl301 b:29.3 occ:1.00 CL32 A:QD6301 0.0 29.3 1.0 C31 A:QD6301 1.9 26.6 1.0 C33 A:QD6301 2.9 26.2 1.0 C30 A:QD6301 2.9 27.8 1.0 H331 A:QD6301 3.0 31.5 1.0 H301 A:QD6301 3.0 33.5 1.0 HE3 A:MET178 3.3 36.9 1.0 HG2 A:MET178 4.0 27.5 1.0 CE A:MET178 4.2 30.7 1.0 C34 A:QD6301 4.2 29.4 1.0 C29 A:QD6301 4.3 26.3 1.0 SD A:MET178 4.4 34.0 1.0 HE1 A:MET178 4.6 36.9 1.0 CG A:MET178 4.6 22.8 1.0 C28 A:QD6301 4.8 25.9 1.0 HG3 A:MET178 4.8 27.5 1.0 HE2 A:MET178 4.9 36.9 1.0 HG22 A:THR174 4.9 30.4 1.0 HG23 A:THR174 5.0 30.4 1.0

T.Dinh, M.Kvaratskhelia. Hiv-1 Integrase Catalytic Core Domain (Ccd) Y99H/A128T Mutant Complexed with Bkc-110 To Be Published.
ISSN: ESSN 2150-7511