Chlorine in PDB 8th4: Structure of AT118-L Nanobody Antagonist in Complex with the Angiotensin II Type I Receptor and Losartan

The binding sites of Chlorine atom in the Structure of AT118-L Nanobody Antagonist in Complex with the Angiotensin II Type I Receptor and Losartan (pdb code 8th4). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Structure of AT118-L Nanobody Antagonist in Complex with the Angiotensin II Type I Receptor and Losartan, PDB code: 8th4:

Chlorine binding site 1 out of 1 in the Structure of AT118-L Nanobody Antagonist in Complex with the Angiotensin II Type I Receptor and Losartan


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Structure of AT118-L Nanobody Antagonist in Complex with the Angiotensin II Type I Receptor and Losartan within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1401 b:81.8 occ:1.00 CL A:LSN1401 0.0 81.8 1.0 C17 A:LSN1401 1.7 63.7 1.0 N6 A:LSN1401 2.7 60.7 1.0 C15 A:LSN1401 2.8 61.1 1.0 C16 A:LSN1401 3.4 63.5 1.0 C18 A:LSN1401 3.8 62.2 1.0 O B:SER102 3.8 85.0 1.0 OG1 A:THR88 3.8 76.0 1.0 N5 A:LSN1401 3.8 61.6 1.0 CB B:SER102 3.9 84.8 1.0 CA B:SER102 4.0 83.4 1.0 CE2 A:TYR87 4.1 72.2 1.0 CE1 A:TYR92 4.2 81.4 1.0 O A:LSN1401 4.3 65.8 1.0 CD2 A:TYR87 4.3 69.8 1.0 C B:SER102 4.4 84.4 1.0 OG B:SER102 4.6 89.1 1.0 CD1 A:TYR92 4.9 83.2 1.0

M.A.Skiba, S.M.Sterling, S.Rawson, S.Zhang, H.Xu, H.Jiang, G.R.Nemeth, M.S.A.Gilman, J.D.Hurley, P.Shen, D.P.Staus, J.Kim, C.Mcmahon, M.K.Lehtinen, H.A.Rockman, P.Barth, L.M.Wingler, A.C.Kruse. Antibodies Expand the Scope of Angiotensin Receptor Pharmacology Nat.Chem.Biol. 2024.
ISSN: ESSN 1552-4469
DOI: 10.1038/S41589-024-01620-6