Chlorine in PDB 8tv1: Structure of the EPHA2 Lbdcrd Bound to FABS1C_L1

All present enzymatic activity of Structure of the EPHA2 Lbdcrd Bound to FABS1C_L1:
2.7.10.1;

The structure of Structure of the EPHA2 Lbdcrd Bound to FABS1C_L1, PDB code: 8tv1 was solved by A.U.Singer, H.A.Bruce, L.Blazer, J.J.Adams, F.Sicheri, S.S.Sidhu, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	62.20 / 2.60
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	123.437, 73.249, 118.57, 90, 107.43, 90
R / Rfree (%)	20.2 / 24.6

The binding sites of Chlorine atom in the Structure of the EPHA2 Lbdcrd Bound to FABS1C_L1 (pdb code 8tv1). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Structure of the EPHA2 Lbdcrd Bound to FABS1C_L1, PDB code: 8tv1:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Structure of the EPHA2 Lbdcrd Bound to FABS1C_L1


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Structure of the EPHA2 Lbdcrd Bound to FABS1C_L1 within 5.0Å range: probe atom residue distance (Å) B Occ D:Cl301 b:75.5 occ:1.00 O D:ASP232 3.8 52.7 1.0 CD1 D:ILE219 4.3 53.7 1.0 C D:ASP232 4.5 50.5 1.0 CB D:ASP232 4.5 45.8 1.0 N D:LYS234 4.9 53.2 1.0

Chlorine binding site 2 out of 2 in the Structure of the EPHA2 Lbdcrd Bound to FABS1C_L1


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Structure of the EPHA2 Lbdcrd Bound to FABS1C_L1 within 5.0Å range: probe atom residue distance (Å) B Occ E:Cl302 b:70.5 occ:1.00 CD E:PRO131 3.8 51.5 1.0 O E:THR219 3.9 56.1 1.0 CG E:PRO131 4.0 51.7 1.0 O E:VAL214 4.0 52.2 1.0 CB E:GLN216 4.1 59.6 1.0 CG2 E:VAL223 4.2 42.5 1.0 CG2 E:THR219 4.2 55.4 1.0 N E:GLN216 4.3 55.6 1.0 OE1 E:GLN216 4.3 59.2 1.0 CG1 E:VAL214 4.3 51.1 1.0 CB E:THR219 4.6 54.8 1.0 C E:THR219 4.6 54.3 1.0 CB E:VAL223 4.6 45.1 1.0 CA E:GLN216 4.8 55.9 1.0 C E:VAL214 4.8 49.5 1.0 N E:VAL223 4.8 46.2 1.0 CB E:VAL214 4.9 48.7 1.0 CB E:ALA130 4.9 51.0 1.0 O E:GLN216 4.9 57.4 1.0 C E:THR215 5.0 55.8 1.0

J.J.Adams, H.A.Bruce, L.Ploder, J.Garcia, G.Khutoreskaya, N.Jarvik, L.E.Costa, M.Gorelik, I.Pot, F.Sicheri, L.L.Blazer, A.U.Singer, S.S.Sidhu. Synthetic Antibodies Targeting EPHA2 Induce Diverse Signaling-Competent Clusters with Differential Activation To Be Published.