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Atomistry » Chlorine » PDB 8tms-8u8w » 8txe | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Chlorine » PDB 8tms-8u8w » 8txe » |
Chlorine in PDB 8txe: Crystal Structure of Kras G12D in Complex with Gdp and Compound 5Enzymatic activity of Crystal Structure of Kras G12D in Complex with Gdp and Compound 5
All present enzymatic activity of Crystal Structure of Kras G12D in Complex with Gdp and Compound 5:
3.6.5.2; Protein crystallography data
The structure of Crystal Structure of Kras G12D in Complex with Gdp and Compound 5, PDB code: 8txe
was solved by
P.Chen,
A.Irimia,
Z.Yang,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 8txe:
The structure of Crystal Structure of Kras G12D in Complex with Gdp and Compound 5 also contains other interesting chemical elements:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Crystal Structure of Kras G12D in Complex with Gdp and Compound 5
(pdb code 8txe). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Crystal Structure of Kras G12D in Complex with Gdp and Compound 5, PDB code: 8txe: Jump to Chlorine binding site number: 1; 2; Chlorine binding site 1 out of 2 in 8txeGo back to Chlorine Binding Sites List in 8txe
Chlorine binding site 1 out
of 2 in the Crystal Structure of Kras G12D in Complex with Gdp and Compound 5
Mono view Stereo pair view
Chlorine binding site 2 out of 2 in 8txeGo back to Chlorine Binding Sites List in 8txe
Chlorine binding site 2 out
of 2 in the Crystal Structure of Kras G12D in Complex with Gdp and Compound 5
Mono view Stereo pair view
Reference:
H.Cheng,
P.Li,
P.Chen,
A.Irimia,
J.H.Bae,
A.Brooun,
P.Fagan,
R.Lam,
B.Lin,
J.Zhang,
X.Zhan,
X.Wu,
N.Xie,
G.Chiang,
R.Shoemaker,
J.M.Vernier.
Structure-Based Design and Synthesis of Potent and Selective Kras G12D Inhibitors. Acs Med.Chem.Lett. V. 14 1351 2023.
Page generated: Thu Dec 28 03:33:15 2023
ISSN: ISSN 1948-5875 PubMed: 37849557 DOI: 10.1021/ACSMEDCHEMLETT.3C00245 |
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