|
Atomistry » Chlorine » PDB 8tms-8u8w » 8u6h | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Chlorine » PDB 8tms-8u8w » 8u6h » |
Chlorine in PDB 8u6h: Crystal Structure of Hiv-1 Reverse Transcriptase in Complex with 3-(2- (2-(3-Acryloyl-2-Oxo-2,3-Dihydro-1H-Benzo[D]Imidazol-1-Yl)Ethoxy)-4- Chlorophenoxy)-5-Chlorobenzonitrile (JLJ744), A Non-Nucleoside InhibitorProtein crystallography data
The structure of Crystal Structure of Hiv-1 Reverse Transcriptase in Complex with 3-(2- (2-(3-Acryloyl-2-Oxo-2,3-Dihydro-1H-Benzo[D]Imidazol-1-Yl)Ethoxy)-4- Chlorophenoxy)-5-Chlorobenzonitrile (JLJ744), A Non-Nucleoside Inhibitor, PDB code: 8u6h
was solved by
G.Prucha,
Z.Carter,
W.L.Jorgensen,
K.S.Anderson,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Crystal Structure of Hiv-1 Reverse Transcriptase in Complex with 3-(2- (2-(3-Acryloyl-2-Oxo-2,3-Dihydro-1H-Benzo[D]Imidazol-1-Yl)Ethoxy)-4- Chlorophenoxy)-5-Chlorobenzonitrile (JLJ744), A Non-Nucleoside Inhibitor
(pdb code 8u6h). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total 4 binding sites of Chlorine where determined in the Crystal Structure of Hiv-1 Reverse Transcriptase in Complex with 3-(2- (2-(3-Acryloyl-2-Oxo-2,3-Dihydro-1H-Benzo[D]Imidazol-1-Yl)Ethoxy)-4- Chlorophenoxy)-5-Chlorobenzonitrile (JLJ744), A Non-Nucleoside Inhibitor, PDB code: 8u6h: Jump to Chlorine binding site number: 1; 2; 3; 4; Chlorine binding site 1 out of 4 in 8u6hGo back to Chlorine Binding Sites List in 8u6h
Chlorine binding site 1 out
of 4 in the Crystal Structure of Hiv-1 Reverse Transcriptase in Complex with 3-(2- (2-(3-Acryloyl-2-Oxo-2,3-Dihydro-1H-Benzo[D]Imidazol-1-Yl)Ethoxy)-4- Chlorophenoxy)-5-Chlorobenzonitrile (JLJ744), A Non-Nucleoside Inhibitor
Mono view Stereo pair view
Chlorine binding site 2 out of 4 in 8u6hGo back to Chlorine Binding Sites List in 8u6h
Chlorine binding site 2 out
of 4 in the Crystal Structure of Hiv-1 Reverse Transcriptase in Complex with 3-(2- (2-(3-Acryloyl-2-Oxo-2,3-Dihydro-1H-Benzo[D]Imidazol-1-Yl)Ethoxy)-4- Chlorophenoxy)-5-Chlorobenzonitrile (JLJ744), A Non-Nucleoside Inhibitor
Mono view Stereo pair view
Chlorine binding site 3 out of 4 in 8u6hGo back to Chlorine Binding Sites List in 8u6h
Chlorine binding site 3 out
of 4 in the Crystal Structure of Hiv-1 Reverse Transcriptase in Complex with 3-(2- (2-(3-Acryloyl-2-Oxo-2,3-Dihydro-1H-Benzo[D]Imidazol-1-Yl)Ethoxy)-4- Chlorophenoxy)-5-Chlorobenzonitrile (JLJ744), A Non-Nucleoside Inhibitor
Mono view Stereo pair view
Chlorine binding site 4 out of 4 in 8u6hGo back to Chlorine Binding Sites List in 8u6h
Chlorine binding site 4 out
of 4 in the Crystal Structure of Hiv-1 Reverse Transcriptase in Complex with 3-(2- (2-(3-Acryloyl-2-Oxo-2,3-Dihydro-1H-Benzo[D]Imidazol-1-Yl)Ethoxy)-4- Chlorophenoxy)-5-Chlorobenzonitrile (JLJ744), A Non-Nucleoside Inhibitor
Mono view Stereo pair view
Reference:
G.R.Prucha,
S.Henry,
K.Hollander,
Z.J.Carter,
K.A.Spasov,
W.L.Jorgensen,
K.S.Anderson.
Covalent and Noncovalent Strategies For Targeting LYS102 in Hiv-1 Reverse Transcriptase. Eur.J.Med.Chem. V. 262 15894 2023.
Page generated: Thu Dec 28 03:35:02 2023
ISSN: ISSN 0223-5234 PubMed: 37883896 DOI: 10.1016/J.EJMECH.2023.115894 |
Last articlesZn in 8WB0Zn in 8WAX Zn in 8WAU Zn in 8WAZ Zn in 8WAY Zn in 8WAV Zn in 8WAW Zn in 8WAT Zn in 8W7M Zn in 8WD3 |
© Copyright 2008-2020 by atomistry.com | ||
Home | Site Map | Copyright | Contact us | Privacy |