Chlorine in PDB 8uqa: Crystal Structure of RNF168 (Ring)-UBCH5C Fused to H2A-H2B Via A 12- Residue Linker

Enzymatic activity of Crystal Structure of RNF168 (Ring)-UBCH5C Fused to H2A-H2B Via A 12- Residue Linker

All present enzymatic activity of Crystal Structure of RNF168 (Ring)-UBCH5C Fused to H2A-H2B Via A 12- Residue Linker:
2.3.2.23; 2.3.2.24; 2.3.2.27;

Protein crystallography data

The structure of Crystal Structure of RNF168 (Ring)-UBCH5C Fused to H2A-H2B Via A 12- Residue Linker, PDB code: 8uqa was solved by Q.Hu, M.V.Botuyan, G.Mer, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 39.18 / 2.05
Space group P 32 2 1
Cell size a, b, c (Å), α, β, γ (°) 102.953, 102.953, 87.231, 90, 90, 120
R / Rfree (%) 19.2 / 23.1

Other elements in 8uqa:

The structure of Crystal Structure of RNF168 (Ring)-UBCH5C Fused to H2A-H2B Via A 12- Residue Linker also contains other interesting chemical elements:

Sodium (Na) 3 atoms
Zinc (Zn) 2 atoms

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Crystal Structure of RNF168 (Ring)-UBCH5C Fused to H2A-H2B Via A 12- Residue Linker (pdb code 8uqa). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 4 binding sites of Chlorine where determined in the Crystal Structure of RNF168 (Ring)-UBCH5C Fused to H2A-H2B Via A 12- Residue Linker, PDB code: 8uqa:
Jump to Chlorine binding site number: 1; 2; 3; 4;

Chlorine binding site 1 out of 4 in 8uqa

Go back to Chlorine Binding Sites List in 8uqa
Chlorine binding site 1 out of 4 in the Crystal Structure of RNF168 (Ring)-UBCH5C Fused to H2A-H2B Via A 12- Residue Linker


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of RNF168 (Ring)-UBCH5C Fused to H2A-H2B Via A 12- Residue Linker within 5.0Å range:
probe atom residue distance (Å) B Occ
K:Cl4005

b:38.2
occ:1.00
O K:HOH5019 3.0 43.4 1.0
O K:HOH5239 3.1 50.2 1.0
N K:GLY3046 3.1 26.6 1.0
CB K:THR2090 3.4 30.7 1.0
CA K:GLY3046 3.4 30.5 1.0
CA K:THR2090 3.5 26.2 1.0
N K:ALA3047 3.5 27.5 1.0
N K:SER2091 3.6 27.9 1.0
C K:GLY3044 3.6 34.1 1.0
O K:HOH5248 3.7 54.8 1.0
CA K:GLY3044 3.7 30.9 1.0
N K:ALA3045 3.8 33.5 1.0
CG2 K:THR2090 3.9 30.1 1.0
C K:GLY3046 3.9 29.8 1.0
C K:THR2090 4.0 27.5 1.0
O K:GLY3044 4.0 29.1 1.0
C K:ALA3045 4.2 30.9 1.0
N K:GLY3044 4.5 30.0 1.0
OG K:SER2091 4.6 37.8 1.0
CA K:ALA3047 4.6 29.2 1.0
CA K:ALA3045 4.6 29.4 1.0
OG1 K:THR2090 4.6 30.3 1.0
O K:ILE2089 4.7 29.6 1.0
CB K:ALA3047 4.7 29.0 1.0
N K:THR2090 4.7 24.2 1.0
CA K:SER2091 4.7 30.8 1.0
CB K:SER2091 4.7 33.9 1.0
O K:GLY3046 5.0 28.8 1.0

Chlorine binding site 2 out of 4 in 8uqa

Go back to Chlorine Binding Sites List in 8uqa
Chlorine binding site 2 out of 4 in the Crystal Structure of RNF168 (Ring)-UBCH5C Fused to H2A-H2B Via A 12- Residue Linker


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of RNF168 (Ring)-UBCH5C Fused to H2A-H2B Via A 12- Residue Linker within 5.0Å range:
probe atom residue distance (Å) B Occ
K:Cl4006

b:41.8
occ:1.00
NE2 K:HIS3082 3.0 33.4 1.0
NH1 K:ARG3081 3.3 59.1 1.0
NZ K:LYS3075 3.6 62.7 1.0
CB K:ASN3073 3.7 54.4 1.0
CD2 K:HIS3082 3.8 31.8 1.0
OD1 K:ASN3073 4.0 59.8 1.0
CG K:ASN3073 4.0 55.5 1.0
CG K:LYS3075 4.0 41.2 1.0
CE1 K:HIS3082 4.0 31.7 1.0
CZ K:ARG3081 4.3 57.3 1.0
CD K:ARG3081 4.3 54.7 1.0
CE K:LYS3075 4.3 49.4 1.0
CD1 K:ILE3079 4.6 36.0 1.0
NE K:ARG3081 4.7 59.6 1.0
CD K:LYS3075 4.8 48.0 1.0
ND2 K:ASN3073 4.9 45.4 1.0
O K:ASN3073 4.9 42.7 1.0

Chlorine binding site 3 out of 4 in 8uqa

Go back to Chlorine Binding Sites List in 8uqa
Chlorine binding site 3 out of 4 in the Crystal Structure of RNF168 (Ring)-UBCH5C Fused to H2A-H2B Via A 12- Residue Linker


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Crystal Structure of RNF168 (Ring)-UBCH5C Fused to H2A-H2B Via A 12- Residue Linker within 5.0Å range:
probe atom residue distance (Å) B Occ
K:Cl4007

b:45.4
occ:1.00
NE K:ARG3035 3.0 49.9 1.0
N K:VAL3043 3.2 26.1 1.0
NH2 K:ARG3035 3.4 52.2 1.0
CA K:ARG3042 3.6 29.9 1.0
CZ K:ARG3035 3.7 51.1 1.0
O K:VAL3043 3.7 27.8 1.0
CB K:ARG3042 3.9 34.0 1.0
C K:ARG3042 3.9 32.2 1.0
CD K:ARG3035 4.1 41.9 1.0
CA K:VAL3043 4.2 25.8 1.0
CG K:ARG3035 4.2 34.1 1.0
C K:VAL3043 4.4 26.1 1.0
CG K:ARG3042 4.4 35.0 1.0
CB K:VAL3043 4.5 28.1 1.0
NH1 K:ARG3042 4.6 46.7 0.0
O K:GLU3041 4.7 29.6 1.0
NE2 K:HIS3031 4.8 35.6 1.0
CZ K:ARG3042 4.8 47.1 0.0
N K:ARG3042 4.9 29.4 1.0
O K:HOH5100 4.9 56.3 1.0
CG2 K:VAL3043 4.9 25.0 1.0
NH1 K:ARG3035 4.9 44.2 1.0

Chlorine binding site 4 out of 4 in 8uqa

Go back to Chlorine Binding Sites List in 8uqa
Chlorine binding site 4 out of 4 in the Crystal Structure of RNF168 (Ring)-UBCH5C Fused to H2A-H2B Via A 12- Residue Linker


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of Crystal Structure of RNF168 (Ring)-UBCH5C Fused to H2A-H2B Via A 12- Residue Linker within 5.0Å range:

Reference:

Q.Hu, M.V.Botuyan, G.Mer. Crystal Structure of RNF168 (Ring)-UBCH5C Fused to H2A-H2B Via A 12-Residue Linker To Be Published.
Page generated: Tue Jul 30 13:17:46 2024

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