Chlorine in PDB 8uqb: Crystal Structure of RNF168 (Ring)-UBCH5C Fused to H2A-H2B Via A 20- Residue Linker (Crystallization Condition 1)

Enzymatic activity of Crystal Structure of RNF168 (Ring)-UBCH5C Fused to H2A-H2B Via A 20- Residue Linker (Crystallization Condition 1)

All present enzymatic activity of Crystal Structure of RNF168 (Ring)-UBCH5C Fused to H2A-H2B Via A 20- Residue Linker (Crystallization Condition 1):
2.3.2.23; 2.3.2.24; 2.3.2.27;

Protein crystallography data

The structure of Crystal Structure of RNF168 (Ring)-UBCH5C Fused to H2A-H2B Via A 20- Residue Linker (Crystallization Condition 1), PDB code: 8uqb was solved by Q.Hu, M.V.Botuyan, G.Mer, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 39.37 / 2.48
Space group P 32 2 1
Cell size a, b, c (Å), α, β, γ (°) 101.948, 101.948, 86.992, 90, 90, 120
R / Rfree (%) 21.8 / 26

Other elements in 8uqb:

The structure of Crystal Structure of RNF168 (Ring)-UBCH5C Fused to H2A-H2B Via A 20- Residue Linker (Crystallization Condition 1) also contains other interesting chemical elements:

Zinc (Zn) 2 atoms

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Crystal Structure of RNF168 (Ring)-UBCH5C Fused to H2A-H2B Via A 20- Residue Linker (Crystallization Condition 1) (pdb code 8uqb). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 4 binding sites of Chlorine where determined in the Crystal Structure of RNF168 (Ring)-UBCH5C Fused to H2A-H2B Via A 20- Residue Linker (Crystallization Condition 1), PDB code: 8uqb:
Jump to Chlorine binding site number: 1; 2; 3; 4;

Chlorine binding site 1 out of 4 in 8uqb

Go back to Chlorine Binding Sites List in 8uqb
Chlorine binding site 1 out of 4 in the Crystal Structure of RNF168 (Ring)-UBCH5C Fused to H2A-H2B Via A 20- Residue Linker (Crystallization Condition 1)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of RNF168 (Ring)-UBCH5C Fused to H2A-H2B Via A 20- Residue Linker (Crystallization Condition 1) within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl4003

b:65.8
occ:1.00
 N A:SER60 3.3 76.6 1.0
N A:SER59 3.4 78.0 1.0
CG A:ARG57 3.7 81.3 1.0
O A:ARG57 3.7 58.2 1.0
CB A:SER59 3.8 79.1 1.0
CB A:ARG57 3.9 75.5 1.0
C A:ARG57 3.9 64.4 1.0
CA A:SER59 3.9 77.0 1.0
OG A:SER59 4.0 88.5 1.0
CB A:SER60 4.0 75.7 1.0
C A:SER59 4.1 75.7 1.0
OG A:SER60 4.1 81.7 1.0
NE A:ARG57 4.2 91.7 1.0
N A:VAL58 4.2 69.7 1.0
C A:VAL58 4.2 72.0 1.0
CA A:SER60 4.3 78.5 1.0
CZ A:ARG57 4.3 96.6 1.0
CA A:VAL58 4.4 67.4 1.0
CA A:ARG57 4.5 73.7 1.0
NH2 A:ARG57 4.6 98.0 1.0
CD A:ARG57 4.6 86.7 1.0
NH1 A:ARG57 4.8 103.1 1.0

Chlorine binding site 2 out of 4 in 8uqb

Go back to Chlorine Binding Sites List in 8uqb
Chlorine binding site 2 out of 4 in the Crystal Structure of RNF168 (Ring)-UBCH5C Fused to H2A-H2B Via A 20- Residue Linker (Crystallization Condition 1)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of RNF168 (Ring)-UBCH5C Fused to H2A-H2B Via A 20- Residue Linker (Crystallization Condition 1) within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl4004

b:50.0
occ:1.00
 OG A:SER1083 3.0 33.9 1.0
NZ A:LYS1066 3.5 54.9 1.0
CA A:SER1083 3.5 31.8 1.0
CB A:SER1083 3.6 35.5 1.0
CB A:ALA1068 3.8 29.6 1.0
NH2 A:ARG1090 4.1 39.3 1.0
N A:SER1083 4.2 34.0 1.0
O A:VAL1067 4.2 32.7 1.0
CD A:LYS1066 4.3 57.1 1.0
CE A:LYS1066 4.5 57.0 1.0
O A:GLY1082 4.7 33.0 1.0
CA A:ALA1068 4.7 36.0 1.0
C A:GLY1082 4.7 35.5 1.0
C A:SER1083 4.7 30.8 1.0
N A:ILE1084 4.8 35.6 1.0
C A:VAL1067 4.9 32.8 1.0
O A:HOH5027 5.0 33.2 1.0

Chlorine binding site 3 out of 4 in 8uqb

Go back to Chlorine Binding Sites List in 8uqb
Chlorine binding site 3 out of 4 in the Crystal Structure of RNF168 (Ring)-UBCH5C Fused to H2A-H2B Via A 20- Residue Linker (Crystallization Condition 1)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Crystal Structure of RNF168 (Ring)-UBCH5C Fused to H2A-H2B Via A 20- Residue Linker (Crystallization Condition 1) within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl4005

b:43.1
occ:1.00
 N A:GLY3046 3.1 35.0 1.0
CA A:THR2090 3.4 35.9 1.0
N A:SER2091 3.4 39.9 1.0
N A:ALA3047 3.5 38.2 1.0
CA A:GLY3046 3.5 38.2 1.0
CB A:THR2090 3.5 39.3 1.0
C A:GLY3044 3.6 39.7 1.0
CA A:GLY3044 3.7 36.7 1.0
N A:ALA3045 3.7 35.8 1.0
C A:GLY3046 3.9 37.1 1.0
CG2 A:THR2090 3.9 29.6 1.0
C A:THR2090 3.9 39.8 1.0
C A:ALA3045 4.2 42.8 1.0
O A:GLY3044 4.2 43.0 1.0
OG A:SER2091 4.5 52.1 1.0
CA A:ALA3045 4.5 43.1 1.0
CA A:ALA3047 4.5 37.9 1.0
O A:ILE2089 4.6 36.7 1.0
N A:GLY3044 4.6 40.8 1.0
CA A:SER2091 4.6 43.5 1.0
CB A:ALA3047 4.6 40.1 1.0
CB A:SER2091 4.6 45.0 1.0
N A:THR2090 4.7 34.0 1.0
OG1 A:THR2090 4.8 40.0 1.0

Chlorine binding site 4 out of 4 in 8uqb

Go back to Chlorine Binding Sites List in 8uqb
Chlorine binding site 4 out of 4 in the Crystal Structure of RNF168 (Ring)-UBCH5C Fused to H2A-H2B Via A 20- Residue Linker (Crystallization Condition 1)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of Crystal Structure of RNF168 (Ring)-UBCH5C Fused to H2A-H2B Via A 20- Residue Linker (Crystallization Condition 1) within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl4006

b:61.2
occ:1.00
 NH1 A:ARG2072 3.6 36.3 1.0
CD2 A:LEU2101 3.7 43.4 1.0
CD A:ARG2072 4.3 40.5 1.0
CG A:LEU2101 4.7 33.0 1.0
CZ A:ARG2072 4.7 40.5 1.0
CB A:LEU2101 4.8 34.2 1.0
CD1 A:LEU2101 5.0 32.4 1.0
NE A:ARG2072 5.0 46.8 1.0

Reference:

Q.Hu, M.V.Botuyan, G.Mer. Crystal Structure of RNF168 (Ring)-UBCH5C Fused to H2A-H2B Via A 20-Residue Linker (Crystallization Condition 1) To Be Published.
Page generated: Tue Jul 30 13:18:14 2024

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