Chlorine in PDB 8ut1: ALPHA7-Nicotinic Acetylcholine Receptor Bound to Epibatidine
Other elements in 8ut1:
The structure of ALPHA7-Nicotinic Acetylcholine Receptor Bound to Epibatidine also contains other interesting chemical elements:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the ALPHA7-Nicotinic Acetylcholine Receptor Bound to Epibatidine
(pdb code 8ut1). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total 5 binding sites of Chlorine where determined in the
ALPHA7-Nicotinic Acetylcholine Receptor Bound to Epibatidine, PDB code: 8ut1:
Jump to Chlorine binding site number:
1;
2;
3;
4;
5;
Chlorine binding site 1 out
of 5 in 8ut1
Go back to
Chlorine Binding Sites List in 8ut1
Chlorine binding site 1 out
of 5 in the ALPHA7-Nicotinic Acetylcholine Receptor Bound to Epibatidine
 Mono view
 Stereo pair view
|
|
A full contact list of Chlorine with other atoms in the Cl binding
site number 1 of ALPHA7-Nicotinic Acetylcholine Receptor Bound to Epibatidine within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Cl606
b:18.8
occ:1.00
|
CL
|
A:EPJ606
|
0.0
|
18.8
|
1.0
|
|
C10
|
A:EPJ606
|
1.7
|
18.8
|
1.0
|
|
N2
|
A:EPJ606
|
2.6
|
18.8
|
1.0
|
|
C9
|
A:EPJ606
|
2.7
|
18.8
|
1.0
|
|
H9
|
A:EPJ606
|
2.8
|
18.8
|
1.0
|
|
HB2
|
B:LEU108
|
3.0
|
16.4
|
1.0
|
|
HB3
|
B:LEU108
|
3.2
|
16.4
|
1.0
|
|
H
|
B:LEU108
|
3.4
|
16.4
|
1.0
|
|
O
|
B:HOH701
|
3.5
|
13.7
|
1.0
|
|
CB
|
B:LEU108
|
3.5
|
16.4
|
1.0
|
|
HB3
|
A:SER149
|
3.6
|
16.5
|
1.0
|
|
O
|
B:ASN106
|
3.7
|
14.5
|
1.0
|
|
O
|
B:GLN116
|
3.8
|
16.7
|
1.0
|
|
HD13
|
B:LEU118
|
3.8
|
14.6
|
1.0
|
|
HB2
|
A:SER149
|
3.8
|
16.5
|
1.0
|
|
C11
|
A:EPJ606
|
3.8
|
18.8
|
1.0
|
|
N
|
B:LEU108
|
3.9
|
16.4
|
1.0
|
|
HA
|
A:SER149
|
3.9
|
16.5
|
1.0
|
|
HA
|
B:TYR117
|
4.0
|
14.7
|
1.0
|
|
C8
|
A:EPJ606
|
4.0
|
18.8
|
1.0
|
|
H
|
B:LEU118
|
4.0
|
14.6
|
1.0
|
|
HD22
|
B:LEU108
|
4.1
|
16.4
|
1.0
|
|
CB
|
A:SER149
|
4.1
|
16.5
|
1.0
|
|
HB2
|
B:LEU118
|
4.2
|
14.6
|
1.0
|
|
HA
|
B:VAL107
|
4.3
|
15.1
|
1.0
|
|
HB2
|
B:GLN116
|
4.3
|
16.7
|
1.0
|
|
HD23
|
B:LEU108
|
4.3
|
16.4
|
1.0
|
|
C
|
B:GLN116
|
4.4
|
16.7
|
1.0
|
|
CA
|
B:LEU108
|
4.4
|
16.4
|
1.0
|
|
HD12
|
B:LEU118
|
4.4
|
14.6
|
1.0
|
|
HB3
|
B:GLN116
|
4.4
|
16.7
|
1.0
|
|
C7
|
A:EPJ606
|
4.4
|
18.8
|
1.0
|
|
C
|
B:ASN106
|
4.5
|
14.5
|
1.0
|
|
CD2
|
B:LEU108
|
4.5
|
16.4
|
1.0
|
|
CD1
|
B:LEU118
|
4.5
|
14.6
|
1.0
|
|
CA
|
A:SER149
|
4.5
|
16.5
|
1.0
|
|
H11
|
A:EPJ606
|
4.6
|
18.8
|
1.0
|
|
N
|
B:LEU118
|
4.6
|
14.6
|
1.0
|
|
CG
|
B:LEU108
|
4.7
|
16.4
|
1.0
|
|
C
|
B:VAL107
|
4.7
|
15.1
|
1.0
|
|
H8
|
A:EPJ606
|
4.7
|
18.8
|
1.0
|
|
CA
|
B:TYR117
|
4.7
|
14.7
|
1.0
|
|
N
|
B:TYR117
|
4.8
|
14.7
|
1.0
|
|
HB2
|
B:ASN106
|
4.8
|
14.5
|
1.0
|
|
CB
|
B:GLN116
|
4.8
|
16.7
|
1.0
|
|
HD1
|
A:TRP148
|
4.8
|
15.7
|
1.0
|
|
CA
|
B:VAL107
|
4.8
|
15.1
|
1.0
|
|
HA
|
B:LEU108
|
4.9
|
16.4
|
1.0
|
|
Chlorine binding site 2 out
of 5 in 8ut1
Go back to
Chlorine Binding Sites List in 8ut1
Chlorine binding site 2 out
of 5 in the ALPHA7-Nicotinic Acetylcholine Receptor Bound to Epibatidine
 Mono view
 Stereo pair view
|
|
A full contact list of Chlorine with other atoms in the Cl binding
site number 2 of ALPHA7-Nicotinic Acetylcholine Receptor Bound to Epibatidine within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Cl607
b:18.8
occ:1.00
|
CL
|
B:EPJ607
|
0.0
|
18.8
|
1.0
|
|
C10
|
B:EPJ607
|
1.7
|
18.8
|
1.0
|
|
N2
|
B:EPJ607
|
2.6
|
18.8
|
1.0
|
|
C9
|
B:EPJ607
|
2.7
|
18.8
|
1.0
|
|
H9
|
B:EPJ607
|
2.8
|
18.8
|
1.0
|
|
HB2
|
C:LEU108
|
3.0
|
16.4
|
1.0
|
|
HB3
|
C:LEU108
|
3.2
|
16.4
|
1.0
|
|
H
|
C:LEU108
|
3.4
|
16.4
|
1.0
|
|
O
|
C:HOH701
|
3.5
|
13.7
|
1.0
|
|
CB
|
C:LEU108
|
3.6
|
16.4
|
1.0
|
|
HB3
|
B:SER149
|
3.6
|
16.5
|
1.0
|
|
O
|
C:ASN106
|
3.7
|
14.5
|
1.0
|
|
HD13
|
C:LEU118
|
3.8
|
14.6
|
1.0
|
|
O
|
C:GLN116
|
3.8
|
16.7
|
1.0
|
|
HB2
|
B:SER149
|
3.8
|
16.5
|
1.0
|
|
C11
|
B:EPJ607
|
3.8
|
18.8
|
1.0
|
|
N
|
C:LEU108
|
3.9
|
16.4
|
1.0
|
|
HA
|
B:SER149
|
3.9
|
16.5
|
1.0
|
|
HA
|
C:TYR117
|
3.9
|
14.7
|
1.0
|
|
C8
|
B:EPJ607
|
4.0
|
18.8
|
1.0
|
|
H
|
C:LEU118
|
4.0
|
14.6
|
1.0
|
|
HD22
|
C:LEU108
|
4.1
|
16.4
|
1.0
|
|
CB
|
B:SER149
|
4.1
|
16.5
|
1.0
|
|
HB2
|
C:LEU118
|
4.2
|
14.6
|
1.0
|
|
HA
|
C:VAL107
|
4.3
|
15.1
|
1.0
|
|
HB2
|
C:GLN116
|
4.3
|
16.7
|
1.0
|
|
HD23
|
C:LEU108
|
4.3
|
16.4
|
1.0
|
|
C
|
C:GLN116
|
4.4
|
16.7
|
1.0
|
|
CA
|
C:LEU108
|
4.4
|
16.4
|
1.0
|
|
HD12
|
C:LEU118
|
4.4
|
14.6
|
1.0
|
|
HB3
|
C:GLN116
|
4.4
|
16.7
|
1.0
|
|
C7
|
B:EPJ607
|
4.4
|
18.8
|
1.0
|
|
C
|
C:ASN106
|
4.5
|
14.5
|
1.0
|
|
CD1
|
C:LEU118
|
4.5
|
14.6
|
1.0
|
|
CA
|
B:SER149
|
4.5
|
16.5
|
1.0
|
|
CD2
|
C:LEU108
|
4.5
|
16.4
|
1.0
|
|
H11
|
B:EPJ607
|
4.6
|
18.8
|
1.0
|
|
N
|
C:LEU118
|
4.6
|
14.6
|
1.0
|
|
CG
|
C:LEU108
|
4.7
|
16.4
|
1.0
|
|
C
|
C:VAL107
|
4.7
|
15.1
|
1.0
|
|
H8
|
B:EPJ607
|
4.7
|
18.8
|
1.0
|
|
CA
|
C:TYR117
|
4.7
|
14.7
|
1.0
|
|
HB2
|
C:ASN106
|
4.8
|
14.5
|
1.0
|
|
N
|
C:TYR117
|
4.8
|
14.7
|
1.0
|
|
CB
|
C:GLN116
|
4.8
|
16.7
|
1.0
|
|
HD1
|
B:TRP148
|
4.8
|
15.7
|
1.0
|
|
CA
|
C:VAL107
|
4.8
|
15.1
|
1.0
|
|
HA
|
C:LEU108
|
4.9
|
16.4
|
1.0
|
|
Chlorine binding site 3 out
of 5 in 8ut1
Go back to
Chlorine Binding Sites List in 8ut1
Chlorine binding site 3 out
of 5 in the ALPHA7-Nicotinic Acetylcholine Receptor Bound to Epibatidine
 Mono view
 Stereo pair view
|
|
A full contact list of Chlorine with other atoms in the Cl binding
site number 3 of ALPHA7-Nicotinic Acetylcholine Receptor Bound to Epibatidine within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:Cl607
b:18.8
occ:1.00
|
CL
|
C:EPJ607
|
0.0
|
18.8
|
1.0
|
|
C10
|
C:EPJ607
|
1.7
|
18.8
|
1.0
|
|
N2
|
C:EPJ607
|
2.6
|
18.8
|
1.0
|
|
C9
|
C:EPJ607
|
2.7
|
18.8
|
1.0
|
|
H9
|
C:EPJ607
|
2.8
|
18.8
|
1.0
|
|
HB2
|
D:LEU108
|
3.0
|
16.4
|
1.0
|
|
HB3
|
D:LEU108
|
3.2
|
16.4
|
1.0
|
|
H
|
D:LEU108
|
3.4
|
16.4
|
1.0
|
|
O
|
D:HOH701
|
3.5
|
13.7
|
1.0
|
|
CB
|
D:LEU108
|
3.6
|
16.4
|
1.0
|
|
HB3
|
C:SER149
|
3.6
|
16.5
|
1.0
|
|
O
|
D:ASN106
|
3.7
|
14.5
|
1.0
|
|
O
|
D:GLN116
|
3.8
|
16.7
|
1.0
|
|
HD13
|
D:LEU118
|
3.8
|
14.6
|
1.0
|
|
HB2
|
C:SER149
|
3.8
|
16.5
|
1.0
|
|
C11
|
C:EPJ607
|
3.8
|
18.8
|
1.0
|
|
N
|
D:LEU108
|
3.9
|
16.4
|
1.0
|
|
HA
|
C:SER149
|
3.9
|
16.5
|
1.0
|
|
HA
|
D:TYR117
|
3.9
|
14.7
|
1.0
|
|
C8
|
C:EPJ607
|
4.0
|
18.8
|
1.0
|
|
H
|
D:LEU118
|
4.0
|
14.6
|
1.0
|
|
HD22
|
D:LEU108
|
4.1
|
16.4
|
1.0
|
|
CB
|
C:SER149
|
4.1
|
16.5
|
1.0
|
|
HB2
|
D:LEU118
|
4.2
|
14.6
|
1.0
|
|
HA
|
D:VAL107
|
4.2
|
15.1
|
1.0
|
|
HB2
|
D:GLN116
|
4.3
|
16.7
|
1.0
|
|
HD23
|
D:LEU108
|
4.3
|
16.4
|
1.0
|
|
C
|
D:GLN116
|
4.4
|
16.7
|
1.0
|
|
CA
|
D:LEU108
|
4.4
|
16.4
|
1.0
|
|
HD12
|
D:LEU118
|
4.4
|
14.6
|
1.0
|
|
HB3
|
D:GLN116
|
4.4
|
16.7
|
1.0
|
|
C7
|
C:EPJ607
|
4.4
|
18.8
|
1.0
|
|
C
|
D:ASN106
|
4.5
|
14.5
|
1.0
|
|
CA
|
C:SER149
|
4.5
|
16.5
|
1.0
|
|
CD2
|
D:LEU108
|
4.5
|
16.4
|
1.0
|
|
CD1
|
D:LEU118
|
4.5
|
14.6
|
1.0
|
|
H11
|
C:EPJ607
|
4.6
|
18.8
|
1.0
|
|
N
|
D:LEU118
|
4.6
|
14.6
|
1.0
|
|
C
|
D:VAL107
|
4.7
|
15.1
|
1.0
|
|
CG
|
D:LEU108
|
4.7
|
16.4
|
1.0
|
|
H8
|
C:EPJ607
|
4.7
|
18.8
|
1.0
|
|
CA
|
D:TYR117
|
4.7
|
14.7
|
1.0
|
|
HB2
|
D:ASN106
|
4.8
|
14.5
|
1.0
|
|
N
|
D:TYR117
|
4.8
|
14.7
|
1.0
|
|
CB
|
D:GLN116
|
4.8
|
16.7
|
1.0
|
|
HD1
|
C:TRP148
|
4.8
|
15.7
|
1.0
|
|
CA
|
D:VAL107
|
4.8
|
15.1
|
1.0
|
|
HA
|
D:LEU108
|
4.9
|
16.4
|
1.0
|
|
Chlorine binding site 4 out
of 5 in 8ut1
Go back to
Chlorine Binding Sites List in 8ut1
Chlorine binding site 4 out
of 5 in the ALPHA7-Nicotinic Acetylcholine Receptor Bound to Epibatidine
 Mono view
 Stereo pair view
|
|
A full contact list of Chlorine with other atoms in the Cl binding
site number 4 of ALPHA7-Nicotinic Acetylcholine Receptor Bound to Epibatidine within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
D:Cl607
b:18.8
occ:1.00
|
CL
|
D:EPJ607
|
0.0
|
18.8
|
1.0
|
|
C10
|
D:EPJ607
|
1.7
|
18.8
|
1.0
|
|
N2
|
D:EPJ607
|
2.6
|
18.8
|
1.0
|
|
C9
|
D:EPJ607
|
2.7
|
18.8
|
1.0
|
|
H9
|
D:EPJ607
|
2.8
|
18.8
|
1.0
|
|
HB2
|
E:LEU108
|
3.0
|
16.4
|
1.0
|
|
HB3
|
E:LEU108
|
3.2
|
16.4
|
1.0
|
|
H
|
E:LEU108
|
3.4
|
16.4
|
1.0
|
|
O
|
E:HOH701
|
3.5
|
13.7
|
1.0
|
|
CB
|
E:LEU108
|
3.6
|
16.4
|
1.0
|
|
HB3
|
D:SER149
|
3.6
|
16.5
|
1.0
|
|
O
|
E:ASN106
|
3.7
|
14.5
|
1.0
|
|
O
|
E:GLN116
|
3.8
|
16.7
|
1.0
|
|
HD13
|
E:LEU118
|
3.8
|
14.6
|
1.0
|
|
HB2
|
D:SER149
|
3.8
|
16.5
|
1.0
|
|
C11
|
D:EPJ607
|
3.8
|
18.8
|
1.0
|
|
N
|
E:LEU108
|
3.9
|
16.4
|
1.0
|
|
HA
|
D:SER149
|
3.9
|
16.5
|
1.0
|
|
HA
|
E:TYR117
|
4.0
|
14.7
|
1.0
|
|
C8
|
D:EPJ607
|
4.0
|
18.8
|
1.0
|
|
H
|
E:LEU118
|
4.1
|
14.6
|
1.0
|
|
HD22
|
E:LEU108
|
4.1
|
16.4
|
1.0
|
|
CB
|
D:SER149
|
4.1
|
16.5
|
1.0
|
|
HB2
|
E:LEU118
|
4.2
|
14.6
|
1.0
|
|
HA
|
E:VAL107
|
4.2
|
15.1
|
1.0
|
|
HB2
|
E:GLN116
|
4.3
|
16.7
|
1.0
|
|
HD23
|
E:LEU108
|
4.3
|
16.4
|
1.0
|
|
CA
|
E:LEU108
|
4.4
|
16.4
|
1.0
|
|
C
|
E:GLN116
|
4.4
|
16.7
|
1.0
|
|
HD12
|
E:LEU118
|
4.4
|
14.6
|
1.0
|
|
HB3
|
E:GLN116
|
4.4
|
16.7
|
1.0
|
|
C7
|
D:EPJ607
|
4.4
|
18.8
|
1.0
|
|
C
|
E:ASN106
|
4.5
|
14.5
|
1.0
|
|
CA
|
D:SER149
|
4.5
|
16.5
|
1.0
|
|
CD2
|
E:LEU108
|
4.5
|
16.4
|
1.0
|
|
CD1
|
E:LEU118
|
4.6
|
14.6
|
1.0
|
|
H11
|
D:EPJ607
|
4.6
|
18.8
|
1.0
|
|
N
|
E:LEU118
|
4.6
|
14.6
|
1.0
|
|
C
|
E:VAL107
|
4.7
|
15.1
|
1.0
|
|
CG
|
E:LEU108
|
4.7
|
16.4
|
1.0
|
|
H8
|
D:EPJ607
|
4.7
|
18.8
|
1.0
|
|
CA
|
E:TYR117
|
4.7
|
14.7
|
1.0
|
|
HB2
|
E:ASN106
|
4.8
|
14.5
|
1.0
|
|
N
|
E:TYR117
|
4.8
|
14.7
|
1.0
|
|
CB
|
E:GLN116
|
4.8
|
16.7
|
1.0
|
|
HD1
|
D:TRP148
|
4.8
|
15.7
|
1.0
|
|
CA
|
E:VAL107
|
4.8
|
15.1
|
1.0
|
|
HA
|
E:LEU108
|
4.9
|
16.4
|
1.0
|
|
Chlorine binding site 5 out
of 5 in 8ut1
Go back to
Chlorine Binding Sites List in 8ut1
Chlorine binding site 5 out
of 5 in the ALPHA7-Nicotinic Acetylcholine Receptor Bound to Epibatidine
 Mono view
 Stereo pair view
|
|
A full contact list of Chlorine with other atoms in the Cl binding
site number 5 of ALPHA7-Nicotinic Acetylcholine Receptor Bound to Epibatidine within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
E:Cl607
b:18.8
occ:1.00
|
CL
|
E:EPJ607
|
0.0
|
18.8
|
1.0
|
|
C10
|
E:EPJ607
|
1.7
|
18.8
|
1.0
|
|
N2
|
E:EPJ607
|
2.6
|
18.8
|
1.0
|
|
C9
|
E:EPJ607
|
2.7
|
18.8
|
1.0
|
|
H9
|
E:EPJ607
|
2.8
|
18.8
|
1.0
|
|
HB2
|
A:LEU108
|
3.0
|
16.4
|
1.0
|
|
HB3
|
A:LEU108
|
3.2
|
16.4
|
1.0
|
|
H
|
A:LEU108
|
3.4
|
16.4
|
1.0
|
|
O
|
A:HOH701
|
3.5
|
13.7
|
1.0
|
|
CB
|
A:LEU108
|
3.5
|
16.4
|
1.0
|
|
HB3
|
E:SER149
|
3.6
|
16.5
|
1.0
|
|
O
|
A:ASN106
|
3.7
|
14.5
|
1.0
|
|
HD13
|
A:LEU118
|
3.8
|
14.6
|
1.0
|
|
O
|
A:GLN116
|
3.8
|
16.7
|
1.0
|
|
HB2
|
E:SER149
|
3.8
|
16.5
|
1.0
|
|
C11
|
E:EPJ607
|
3.8
|
18.8
|
1.0
|
|
N
|
A:LEU108
|
3.9
|
16.4
|
1.0
|
|
HA
|
E:SER149
|
3.9
|
16.5
|
1.0
|
|
C8
|
E:EPJ607
|
4.0
|
18.8
|
1.0
|
|
HA
|
A:TYR117
|
4.0
|
14.7
|
1.0
|
|
H
|
A:LEU118
|
4.1
|
14.6
|
1.0
|
|
HD22
|
A:LEU108
|
4.1
|
16.4
|
1.0
|
|
CB
|
E:SER149
|
4.1
|
16.5
|
1.0
|
|
HB2
|
A:LEU118
|
4.2
|
14.6
|
1.0
|
|
HA
|
A:VAL107
|
4.3
|
15.1
|
1.0
|
|
HB2
|
A:GLN116
|
4.3
|
16.7
|
1.0
|
|
HD23
|
A:LEU108
|
4.3
|
16.4
|
1.0
|
|
CA
|
A:LEU108
|
4.4
|
16.4
|
1.0
|
|
C
|
A:GLN116
|
4.4
|
16.7
|
1.0
|
|
HD12
|
A:LEU118
|
4.4
|
14.6
|
1.0
|
|
HB3
|
A:GLN116
|
4.4
|
16.7
|
1.0
|
|
C7
|
E:EPJ607
|
4.4
|
18.8
|
1.0
|
|
C
|
A:ASN106
|
4.5
|
14.5
|
1.0
|
|
CD2
|
A:LEU108
|
4.5
|
16.4
|
1.0
|
|
CA
|
E:SER149
|
4.5
|
16.5
|
1.0
|
|
CD1
|
A:LEU118
|
4.5
|
14.6
|
1.0
|
|
H11
|
E:EPJ607
|
4.6
|
18.8
|
1.0
|
|
N
|
A:LEU118
|
4.7
|
14.6
|
1.0
|
|
CG
|
A:LEU108
|
4.7
|
16.4
|
1.0
|
|
C
|
A:VAL107
|
4.7
|
15.1
|
1.0
|
|
H8
|
E:EPJ607
|
4.7
|
18.8
|
1.0
|
|
CA
|
A:TYR117
|
4.7
|
14.7
|
1.0
|
|
HB2
|
A:ASN106
|
4.8
|
14.5
|
1.0
|
|
N
|
A:TYR117
|
4.8
|
14.7
|
1.0
|
|
CB
|
A:GLN116
|
4.8
|
16.7
|
1.0
|
|
HD1
|
E:TRP148
|
4.8
|
15.7
|
1.0
|
|
CA
|
A:VAL107
|
4.8
|
15.1
|
1.0
|
|
HA
|
A:LEU108
|
4.9
|
16.4
|
1.0
|
|
Reference:
S.M.Burke,
M.Avstrikova,
C.M.Noviello,
N.Mukhtasimova,
J.P.Changeux,
G.A.Thakur,
S.M.Sine,
M.Cecchini,
R.E.Hibbs.
ALPHA7-Nicotinic Acetylcholine Receptor Bound to Epibatidine To Be Published.
Page generated: Tue Jul 30 13:26:34 2024
|
