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Atomistry » Chlorine » PDB 8upc-8v4o » 8v1o | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Chlorine » PDB 8upc-8v4o » 8v1o » |
Chlorine in PDB 8v1o: Crystal Structure of IRAK4 Kinase Domain with Compound 4Enzymatic activity of Crystal Structure of IRAK4 Kinase Domain with Compound 4
All present enzymatic activity of Crystal Structure of IRAK4 Kinase Domain with Compound 4:
2.7.11.1; Protein crystallography data
The structure of Crystal Structure of IRAK4 Kinase Domain with Compound 4, PDB code: 8v1o
was solved by
M.M.Weiss,
X.Zheng,
C.M.Browne,
V.Campbell,
D.Chen,
B.Enerson,
X.Fei,
X.Huang,
C.R.Klaus,
H.Li,
M.Mayo,
A.A.Mcdonald,
A.Paul,
K.Sharma,
Y.Shi,
A.Slavin,
D.M.Walter,
K.Yuan,
Y.Zhang,
X.Zhu,
J.Kelleher,
N.Ji,
D.Walker,
N.Mainolfi,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 8v1o:
The structure of Crystal Structure of IRAK4 Kinase Domain with Compound 4 also contains other interesting chemical elements:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Crystal Structure of IRAK4 Kinase Domain with Compound 4
(pdb code 8v1o). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of IRAK4 Kinase Domain with Compound 4, PDB code: 8v1o: Chlorine binding site 1 out of 1 in 8v1oGo back to Chlorine Binding Sites List in 8v1o
Chlorine binding site 1 out
of 1 in the Crystal Structure of IRAK4 Kinase Domain with Compound 4
Mono view Stereo pair view
Reference:
M.M.Weiss,
X.Zheng,
N.Ji,
C.M.Browne,
V.Campbell,
D.Chen,
B.Enerson,
X.Fei,
X.Huang,
C.R.Klaus,
H.Li,
M.Mayo,
A.A.Mcdonald,
A.Paul,
H.Rong,
K.Sharma,
Y.Shi,
A.Slavin,
D.M.Walther,
K.Yuan,
Y.Zhang,
X.Zhu,
J.Kelleher,
D.Walker,
N.Mainolfi.
Discovery of Kt-413, A Targeted Protein Degrader of IRAK4 and Imid Substrates Targeting MYD88 Mutant Diffuse Large B-Cell Lymphoma J.Med.Chem. 2024.
Page generated: Tue Jul 30 13:29:08 2024
ISSN: ISSN 0022-2623 DOI: 10.1021/ACS.JMEDCHEM.3C01823 |
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