Chlorine in PDB 8v8a: ALPHA7-Nicotinic Acetylcholine Receptor Time Resolved Bound to Epibatidine and Pnu-120596 Desensitized Intermediate State
Other elements in 8v8a:
The structure of ALPHA7-Nicotinic Acetylcholine Receptor Time Resolved Bound to Epibatidine and Pnu-120596 Desensitized Intermediate State also contains other interesting chemical elements:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the ALPHA7-Nicotinic Acetylcholine Receptor Time Resolved Bound to Epibatidine and Pnu-120596 Desensitized Intermediate State
(pdb code 8v8a). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total 10 binding sites of Chlorine where determined in the
ALPHA7-Nicotinic Acetylcholine Receptor Time Resolved Bound to Epibatidine and Pnu-120596 Desensitized Intermediate State, PDB code: 8v8a:
Jump to Chlorine binding site number:
1;
2;
3;
4;
5;
6;
7;
8;
9;
10;
Chlorine binding site 1 out
of 10 in 8v8a
Go back to
Chlorine Binding Sites List in 8v8a
Chlorine binding site 1 out
of 10 in the ALPHA7-Nicotinic Acetylcholine Receptor Time Resolved Bound to Epibatidine and Pnu-120596 Desensitized Intermediate State
 Mono view
 Stereo pair view
|
|
A full contact list of Chlorine with other atoms in the Cl binding
site number 1 of ALPHA7-Nicotinic Acetylcholine Receptor Time Resolved Bound to Epibatidine and Pnu-120596 Desensitized Intermediate State within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Cl606
b:2.2
occ:1.00
|
CL
|
A:EPJ606
|
0.0
|
2.2
|
1.0
|
|
C10
|
A:EPJ606
|
1.7
|
2.2
|
1.0
|
|
N2
|
A:EPJ606
|
2.6
|
2.2
|
1.0
|
|
C9
|
A:EPJ606
|
2.7
|
2.2
|
1.0
|
|
HB2
|
B:LEU108
|
2.8
|
0.2
|
1.0
|
|
H9
|
A:EPJ606
|
2.8
|
2.2
|
1.0
|
|
HB3
|
B:LEU108
|
3.0
|
0.2
|
1.0
|
|
H
|
B:LEU108
|
3.1
|
0.2
|
1.0
|
|
O
|
B:GLN116
|
3.1
|
0.2
|
1.0
|
|
O
|
B:HOH710
|
3.3
|
2.8
|
1.0
|
|
CB
|
B:LEU108
|
3.3
|
0.2
|
1.0
|
|
O
|
B:ASN106
|
3.4
|
0.0
|
1.0
|
|
HD13
|
B:LEU118
|
3.6
|
0.2
|
1.0
|
|
N
|
B:LEU108
|
3.6
|
0.2
|
1.0
|
|
HB2
|
A:SER149
|
3.7
|
1.1
|
1.0
|
|
H
|
B:LEU118
|
3.8
|
0.2
|
1.0
|
|
HB3
|
A:SER149
|
3.8
|
1.1
|
1.0
|
|
HB3
|
B:GLN116
|
3.8
|
0.2
|
1.0
|
|
C11
|
A:EPJ606
|
3.8
|
2.2
|
1.0
|
|
HA
|
B:TYR117
|
3.9
|
0.1
|
1.0
|
|
C
|
B:GLN116
|
3.9
|
0.2
|
1.0
|
|
HD22
|
B:LEU108
|
3.9
|
0.2
|
1.0
|
|
C8
|
A:EPJ606
|
4.0
|
2.2
|
1.0
|
|
HA
|
B:VAL107
|
4.0
|
0.1
|
1.0
|
|
HB2
|
B:LEU118
|
4.0
|
0.2
|
1.0
|
|
HB2
|
B:GLN116
|
4.1
|
0.2
|
1.0
|
|
HD23
|
B:LEU108
|
4.1
|
0.2
|
1.0
|
|
CA
|
B:LEU108
|
4.1
|
0.2
|
1.0
|
|
CB
|
A:SER149
|
4.2
|
1.1
|
1.0
|
|
HA
|
A:SER149
|
4.2
|
1.1
|
1.0
|
|
CD2
|
B:LEU108
|
4.3
|
0.2
|
1.0
|
|
CB
|
B:GLN116
|
4.4
|
0.2
|
1.0
|
|
C
|
B:ASN106
|
4.4
|
0.0
|
1.0
|
|
N
|
B:LEU118
|
4.4
|
0.2
|
1.0
|
|
C
|
B:VAL107
|
4.4
|
0.1
|
1.0
|
|
CD1
|
B:LEU118
|
4.4
|
0.2
|
1.0
|
|
C7
|
A:EPJ606
|
4.5
|
2.2
|
1.0
|
|
HD12
|
B:LEU118
|
4.5
|
0.2
|
1.0
|
|
CG
|
B:LEU108
|
4.5
|
0.2
|
1.0
|
|
H11
|
A:EPJ606
|
4.6
|
2.2
|
1.0
|
|
CA
|
B:TYR117
|
4.6
|
0.1
|
1.0
|
|
CA
|
B:VAL107
|
4.6
|
0.1
|
1.0
|
|
N
|
B:TYR117
|
4.6
|
0.1
|
1.0
|
|
HA
|
B:LEU108
|
4.6
|
0.2
|
1.0
|
|
H8
|
A:EPJ606
|
4.7
|
2.2
|
1.0
|
|
CA
|
A:SER149
|
4.7
|
1.1
|
1.0
|
|
CA
|
B:GLN116
|
4.8
|
0.2
|
1.0
|
|
CB
|
B:LEU118
|
4.9
|
0.2
|
1.0
|
|
N
|
B:VAL107
|
4.9
|
0.1
|
1.0
|
|
C
|
B:TYR117
|
4.9
|
0.1
|
1.0
|
|
HB2
|
B:ASN106
|
5.0
|
0.0
|
1.0
|
|
Chlorine binding site 2 out
of 10 in 8v8a
Go back to
Chlorine Binding Sites List in 8v8a
Chlorine binding site 2 out
of 10 in the ALPHA7-Nicotinic Acetylcholine Receptor Time Resolved Bound to Epibatidine and Pnu-120596 Desensitized Intermediate State
 Mono view
 Stereo pair view
|
|
A full contact list of Chlorine with other atoms in the Cl binding
site number 2 of ALPHA7-Nicotinic Acetylcholine Receptor Time Resolved Bound to Epibatidine and Pnu-120596 Desensitized Intermediate State within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Cl608
b:10.6
occ:1.00
|
CL1
|
A:I34608
|
0.0
|
10.6
|
1.0
|
|
C20
|
A:I34608
|
1.7
|
10.6
|
1.0
|
|
HD11
|
A:ILE221
|
2.6
|
8.4
|
1.0
|
|
C19
|
A:I34608
|
2.7
|
10.6
|
1.0
|
|
C03
|
A:I34608
|
2.7
|
10.6
|
1.0
|
|
HE1
|
E:MET278
|
2.8
|
11.5
|
1.0
|
|
H12
|
A:I34608
|
2.8
|
10.6
|
1.0
|
|
HB3
|
A:PRO217
|
2.8
|
6.9
|
1.0
|
|
O02
|
A:I34608
|
2.9
|
10.6
|
1.0
|
|
H21J
|
E:POV605
|
2.9
|
15.4
|
1.0
|
|
HG22
|
E:THR250
|
3.1
|
8.8
|
1.0
|
|
HE2
|
E:MET278
|
3.4
|
11.5
|
1.0
|
|
CE
|
E:MET278
|
3.4
|
11.5
|
1.0
|
|
CD1
|
A:ILE221
|
3.5
|
8.4
|
1.0
|
|
HZ
|
A:PHE252
|
3.5
|
7.5
|
1.0
|
|
H21F
|
E:POV605
|
3.5
|
15.4
|
1.0
|
|
HD12
|
A:ILE221
|
3.6
|
8.4
|
1.0
|
|
CB
|
A:PRO217
|
3.8
|
6.9
|
1.0
|
|
C218
|
E:POV605
|
3.8
|
15.4
|
1.0
|
|
SD
|
E:MET278
|
3.9
|
11.5
|
1.0
|
|
C08
|
A:I34608
|
4.0
|
10.6
|
1.0
|
|
HD13
|
A:ILE221
|
4.0
|
8.4
|
1.0
|
|
C04
|
A:I34608
|
4.0
|
10.6
|
1.0
|
|
CG2
|
E:THR250
|
4.0
|
8.8
|
1.0
|
|
HB2
|
A:PRO217
|
4.0
|
6.9
|
1.0
|
|
H21H
|
E:POV605
|
4.2
|
15.4
|
1.0
|
|
HG21
|
E:THR250
|
4.2
|
8.8
|
1.0
|
|
HE3
|
E:MET278
|
4.3
|
11.5
|
1.0
|
|
C01
|
A:I34608
|
4.3
|
10.6
|
1.0
|
|
HG13
|
A:ILE221
|
4.3
|
8.4
|
1.0
|
|
HG3
|
A:PRO217
|
4.4
|
6.9
|
1.0
|
|
C216
|
E:POV605
|
4.4
|
15.4
|
1.0
|
|
CZ
|
A:PHE252
|
4.4
|
7.5
|
1.0
|
|
H218
|
E:POV605
|
4.4
|
15.4
|
1.0
|
|
CG1
|
A:ILE221
|
4.5
|
8.4
|
1.0
|
|
HA
|
E:THR250
|
4.5
|
8.8
|
1.0
|
|
C05
|
A:I34608
|
4.5
|
10.6
|
1.0
|
|
C217
|
E:POV605
|
4.5
|
15.4
|
1.0
|
|
HA
|
A:PRO217
|
4.5
|
6.9
|
1.0
|
|
HG23
|
E:THR250
|
4.5
|
8.8
|
1.0
|
|
CG
|
A:PRO217
|
4.5
|
6.9
|
1.0
|
|
H217
|
E:POV605
|
4.6
|
15.4
|
1.0
|
|
HB
|
E:THR250
|
4.6
|
8.8
|
1.0
|
|
HG12
|
A:ILE221
|
4.6
|
8.4
|
1.0
|
|
H1
|
A:I34608
|
4.6
|
10.6
|
1.0
|
|
SD
|
E:MET253
|
4.7
|
8.7
|
0.5
|
|
CA
|
A:PRO217
|
4.7
|
6.9
|
1.0
|
|
HG2
|
A:PRO217
|
4.7
|
6.9
|
1.0
|
|
H4
|
A:I34608
|
4.7
|
10.6
|
1.0
|
|
H3
|
A:I34608
|
4.7
|
10.6
|
1.0
|
|
H2
|
A:I34608
|
4.7
|
10.6
|
1.0
|
|
HG3
|
E:MET253
|
4.8
|
8.7
|
0.5
|
|
CB
|
E:THR250
|
4.8
|
8.8
|
1.0
|
|
H216
|
E:POV605
|
4.9
|
15.4
|
1.0
|
|
HE1
|
A:PHE252
|
4.9
|
7.5
|
1.0
|
|
HB2
|
E:MET253
|
4.9
|
8.7
|
0.5
|
|
HB2
|
E:MET253
|
4.9
|
8.7
|
0.5
|
|
O11
|
A:I34608
|
5.0
|
10.6
|
1.0
|
|
Chlorine binding site 3 out
of 10 in 8v8a
Go back to
Chlorine Binding Sites List in 8v8a
Chlorine binding site 3 out
of 10 in the ALPHA7-Nicotinic Acetylcholine Receptor Time Resolved Bound to Epibatidine and Pnu-120596 Desensitized Intermediate State
 Mono view
 Stereo pair view
|
|
A full contact list of Chlorine with other atoms in the Cl binding
site number 3 of ALPHA7-Nicotinic Acetylcholine Receptor Time Resolved Bound to Epibatidine and Pnu-120596 Desensitized Intermediate State within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Cl602
b:10.6
occ:1.00
|
CL1
|
B:I34602
|
0.0
|
10.6
|
1.0
|
|
C20
|
B:I34602
|
1.7
|
10.6
|
1.0
|
|
HD11
|
B:ILE221
|
2.6
|
8.4
|
1.0
|
|
C19
|
B:I34602
|
2.7
|
10.6
|
1.0
|
|
C03
|
B:I34602
|
2.7
|
10.6
|
1.0
|
|
HE1
|
A:MET278
|
2.8
|
11.5
|
1.0
|
|
H12
|
B:I34602
|
2.8
|
10.6
|
1.0
|
|
HB3
|
B:PRO217
|
2.8
|
6.9
|
1.0
|
|
O02
|
B:I34602
|
2.9
|
10.6
|
1.0
|
|
H21J
|
A:POV603
|
2.9
|
15.4
|
1.0
|
|
HG22
|
A:THR250
|
3.1
|
8.8
|
1.0
|
|
HE2
|
A:MET278
|
3.4
|
11.5
|
1.0
|
|
CE
|
A:MET278
|
3.4
|
11.5
|
1.0
|
|
CD1
|
B:ILE221
|
3.5
|
8.4
|
1.0
|
|
H21F
|
A:POV603
|
3.5
|
15.4
|
1.0
|
|
HZ
|
B:PHE252
|
3.5
|
7.5
|
1.0
|
|
HD12
|
B:ILE221
|
3.6
|
8.4
|
1.0
|
|
CB
|
B:PRO217
|
3.8
|
6.9
|
1.0
|
|
C218
|
A:POV603
|
3.8
|
15.4
|
1.0
|
|
SD
|
A:MET278
|
3.9
|
11.5
|
1.0
|
|
HD13
|
B:ILE221
|
4.0
|
8.4
|
1.0
|
|
C08
|
B:I34602
|
4.0
|
10.6
|
1.0
|
|
C04
|
B:I34602
|
4.0
|
10.6
|
1.0
|
|
CG2
|
A:THR250
|
4.0
|
8.8
|
1.0
|
|
HB2
|
B:PRO217
|
4.0
|
6.9
|
1.0
|
|
H21H
|
A:POV603
|
4.2
|
15.4
|
1.0
|
|
HG21
|
A:THR250
|
4.2
|
8.8
|
1.0
|
|
HE3
|
A:MET278
|
4.3
|
11.5
|
1.0
|
|
C01
|
B:I34602
|
4.3
|
10.6
|
1.0
|
|
HG13
|
B:ILE221
|
4.3
|
8.4
|
1.0
|
|
C216
|
A:POV603
|
4.4
|
15.4
|
1.0
|
|
HG3
|
B:PRO217
|
4.4
|
6.9
|
1.0
|
|
H218
|
A:POV603
|
4.4
|
15.4
|
1.0
|
|
CZ
|
B:PHE252
|
4.4
|
7.5
|
1.0
|
|
CG1
|
B:ILE221
|
4.5
|
8.4
|
1.0
|
|
HA
|
A:THR250
|
4.5
|
8.8
|
1.0
|
|
C05
|
B:I34602
|
4.5
|
10.6
|
1.0
|
|
C217
|
A:POV603
|
4.5
|
15.4
|
1.0
|
|
HA
|
B:PRO217
|
4.5
|
6.9
|
1.0
|
|
HG23
|
A:THR250
|
4.5
|
8.8
|
1.0
|
|
CG
|
B:PRO217
|
4.6
|
6.9
|
1.0
|
|
H217
|
A:POV603
|
4.6
|
15.4
|
1.0
|
|
HB
|
A:THR250
|
4.6
|
8.8
|
1.0
|
|
HG12
|
B:ILE221
|
4.6
|
8.4
|
1.0
|
|
H1
|
B:I34602
|
4.6
|
10.6
|
1.0
|
|
SD
|
A:MET253
|
4.7
|
8.7
|
0.5
|
|
CA
|
B:PRO217
|
4.7
|
6.9
|
1.0
|
|
HG2
|
B:PRO217
|
4.7
|
6.9
|
1.0
|
|
H4
|
B:I34602
|
4.7
|
10.6
|
1.0
|
|
H3
|
B:I34602
|
4.7
|
10.6
|
1.0
|
|
H2
|
B:I34602
|
4.7
|
10.6
|
1.0
|
|
HG3
|
A:MET253
|
4.8
|
8.7
|
0.5
|
|
CB
|
A:THR250
|
4.8
|
8.8
|
1.0
|
|
H216
|
A:POV603
|
4.9
|
15.4
|
1.0
|
|
HB2
|
A:MET253
|
4.9
|
8.7
|
0.5
|
|
HE1
|
B:PHE252
|
4.9
|
7.5
|
1.0
|
|
HB2
|
A:MET253
|
4.9
|
8.7
|
0.5
|
|
O11
|
B:I34602
|
5.0
|
10.6
|
1.0
|
|
Chlorine binding site 4 out
of 10 in 8v8a
Go back to
Chlorine Binding Sites List in 8v8a
Chlorine binding site 4 out
of 10 in the ALPHA7-Nicotinic Acetylcholine Receptor Time Resolved Bound to Epibatidine and Pnu-120596 Desensitized Intermediate State
 Mono view
 Stereo pair view
|
|
A full contact list of Chlorine with other atoms in the Cl binding
site number 4 of ALPHA7-Nicotinic Acetylcholine Receptor Time Resolved Bound to Epibatidine and Pnu-120596 Desensitized Intermediate State within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Cl608
b:2.2
occ:1.00
|
CL
|
B:EPJ608
|
0.0
|
2.2
|
1.0
|
|
C10
|
B:EPJ608
|
1.7
|
2.2
|
1.0
|
|
N2
|
B:EPJ608
|
2.6
|
2.2
|
1.0
|
|
C9
|
B:EPJ608
|
2.7
|
2.2
|
1.0
|
|
HB2
|
C:LEU108
|
2.8
|
0.2
|
1.0
|
|
H9
|
B:EPJ608
|
2.8
|
2.2
|
1.0
|
|
HB3
|
C:LEU108
|
3.0
|
0.2
|
1.0
|
|
H
|
C:LEU108
|
3.1
|
0.2
|
1.0
|
|
O
|
C:GLN116
|
3.1
|
0.2
|
1.0
|
|
O
|
C:HOH710
|
3.3
|
2.8
|
1.0
|
|
CB
|
C:LEU108
|
3.3
|
0.2
|
1.0
|
|
O
|
C:ASN106
|
3.4
|
0.0
|
1.0
|
|
HD13
|
C:LEU118
|
3.6
|
0.2
|
1.0
|
|
N
|
C:LEU108
|
3.6
|
0.2
|
1.0
|
|
HB2
|
B:SER149
|
3.7
|
1.1
|
1.0
|
|
H
|
C:LEU118
|
3.8
|
0.2
|
1.0
|
|
HB3
|
B:SER149
|
3.8
|
1.1
|
1.0
|
|
HB3
|
C:GLN116
|
3.8
|
0.2
|
1.0
|
|
C11
|
B:EPJ608
|
3.8
|
2.2
|
1.0
|
|
HA
|
C:TYR117
|
3.9
|
0.1
|
1.0
|
|
C
|
C:GLN116
|
3.9
|
0.2
|
1.0
|
|
HD22
|
C:LEU108
|
3.9
|
0.2
|
1.0
|
|
C8
|
B:EPJ608
|
4.0
|
2.2
|
1.0
|
|
HA
|
C:VAL107
|
4.0
|
0.1
|
1.0
|
|
HB2
|
C:LEU118
|
4.0
|
0.2
|
1.0
|
|
HB2
|
C:GLN116
|
4.0
|
0.2
|
1.0
|
|
HD23
|
C:LEU108
|
4.0
|
0.2
|
1.0
|
|
CA
|
C:LEU108
|
4.1
|
0.2
|
1.0
|
|
CB
|
B:SER149
|
4.2
|
1.1
|
1.0
|
|
HA
|
B:SER149
|
4.2
|
1.1
|
1.0
|
|
CD2
|
C:LEU108
|
4.3
|
0.2
|
1.0
|
|
CB
|
C:GLN116
|
4.4
|
0.2
|
1.0
|
|
C
|
C:ASN106
|
4.4
|
0.0
|
1.0
|
|
N
|
C:LEU118
|
4.4
|
0.2
|
1.0
|
|
C
|
C:VAL107
|
4.4
|
0.1
|
1.0
|
|
CD1
|
C:LEU118
|
4.4
|
0.2
|
1.0
|
|
C7
|
B:EPJ608
|
4.5
|
2.2
|
1.0
|
|
HD12
|
C:LEU118
|
4.5
|
0.2
|
1.0
|
|
CG
|
C:LEU108
|
4.5
|
0.2
|
1.0
|
|
H11
|
B:EPJ608
|
4.6
|
2.2
|
1.0
|
|
CA
|
C:TYR117
|
4.6
|
0.1
|
1.0
|
|
CA
|
C:VAL107
|
4.6
|
0.1
|
1.0
|
|
N
|
C:TYR117
|
4.6
|
0.1
|
1.0
|
|
HA
|
C:LEU108
|
4.6
|
0.2
|
1.0
|
|
H8
|
B:EPJ608
|
4.7
|
2.2
|
1.0
|
|
CA
|
B:SER149
|
4.7
|
1.1
|
1.0
|
|
CA
|
C:GLN116
|
4.8
|
0.2
|
1.0
|
|
CB
|
C:LEU118
|
4.9
|
0.2
|
1.0
|
|
N
|
C:VAL107
|
4.9
|
0.1
|
1.0
|
|
C
|
C:TYR117
|
4.9
|
0.1
|
1.0
|
|
Chlorine binding site 5 out
of 10 in 8v8a
Go back to
Chlorine Binding Sites List in 8v8a
Chlorine binding site 5 out
of 10 in the ALPHA7-Nicotinic Acetylcholine Receptor Time Resolved Bound to Epibatidine and Pnu-120596 Desensitized Intermediate State
 Mono view
 Stereo pair view
|
|
A full contact list of Chlorine with other atoms in the Cl binding
site number 5 of ALPHA7-Nicotinic Acetylcholine Receptor Time Resolved Bound to Epibatidine and Pnu-120596 Desensitized Intermediate State within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:Cl602
b:10.6
occ:1.00
|
CL1
|
C:I34602
|
0.0
|
10.6
|
1.0
|
|
C20
|
C:I34602
|
1.7
|
10.6
|
1.0
|
|
HD11
|
C:ILE221
|
2.6
|
8.4
|
1.0
|
|
C19
|
C:I34602
|
2.7
|
10.6
|
1.0
|
|
C03
|
C:I34602
|
2.7
|
10.6
|
1.0
|
|
HE1
|
B:MET278
|
2.8
|
11.5
|
1.0
|
|
H12
|
C:I34602
|
2.8
|
10.6
|
1.0
|
|
HB3
|
C:PRO217
|
2.8
|
6.9
|
1.0
|
|
O02
|
C:I34602
|
2.9
|
10.6
|
1.0
|
|
H21J
|
B:POV605
|
2.9
|
15.4
|
1.0
|
|
HG22
|
B:THR250
|
3.1
|
8.8
|
1.0
|
|
HE2
|
B:MET278
|
3.4
|
11.5
|
1.0
|
|
CE
|
B:MET278
|
3.4
|
11.5
|
1.0
|
|
CD1
|
C:ILE221
|
3.5
|
8.4
|
1.0
|
|
HZ
|
C:PHE252
|
3.5
|
7.5
|
1.0
|
|
H21F
|
B:POV605
|
3.5
|
15.4
|
1.0
|
|
HD12
|
C:ILE221
|
3.6
|
8.4
|
1.0
|
|
CB
|
C:PRO217
|
3.8
|
6.9
|
1.0
|
|
C218
|
B:POV605
|
3.8
|
15.4
|
1.0
|
|
SD
|
B:MET278
|
3.9
|
11.5
|
1.0
|
|
HD13
|
C:ILE221
|
4.0
|
8.4
|
1.0
|
|
C08
|
C:I34602
|
4.0
|
10.6
|
1.0
|
|
C04
|
C:I34602
|
4.0
|
10.6
|
1.0
|
|
CG2
|
B:THR250
|
4.0
|
8.8
|
1.0
|
|
HB2
|
C:PRO217
|
4.0
|
6.9
|
1.0
|
|
H21H
|
B:POV605
|
4.2
|
15.4
|
1.0
|
|
HG21
|
B:THR250
|
4.2
|
8.8
|
1.0
|
|
HE3
|
B:MET278
|
4.3
|
11.5
|
1.0
|
|
C01
|
C:I34602
|
4.3
|
10.6
|
1.0
|
|
HG13
|
C:ILE221
|
4.3
|
8.4
|
1.0
|
|
HG3
|
C:PRO217
|
4.4
|
6.9
|
1.0
|
|
C216
|
B:POV605
|
4.4
|
15.4
|
1.0
|
|
CZ
|
C:PHE252
|
4.4
|
7.5
|
1.0
|
|
H218
|
B:POV605
|
4.4
|
15.4
|
1.0
|
|
CG1
|
C:ILE221
|
4.5
|
8.4
|
1.0
|
|
HA
|
B:THR250
|
4.5
|
8.8
|
1.0
|
|
C05
|
C:I34602
|
4.5
|
10.6
|
1.0
|
|
C217
|
B:POV605
|
4.5
|
15.4
|
1.0
|
|
HA
|
C:PRO217
|
4.5
|
6.9
|
1.0
|
|
HG23
|
B:THR250
|
4.5
|
8.8
|
1.0
|
|
CG
|
C:PRO217
|
4.5
|
6.9
|
1.0
|
|
H217
|
B:POV605
|
4.6
|
15.4
|
1.0
|
|
HB
|
B:THR250
|
4.6
|
8.8
|
1.0
|
|
HG12
|
C:ILE221
|
4.6
|
8.4
|
1.0
|
|
H1
|
C:I34602
|
4.6
|
10.6
|
1.0
|
|
CA
|
C:PRO217
|
4.7
|
6.9
|
1.0
|
|
SD
|
B:MET253
|
4.7
|
8.7
|
0.5
|
|
HG2
|
C:PRO217
|
4.7
|
6.9
|
1.0
|
|
H4
|
C:I34602
|
4.7
|
10.6
|
1.0
|
|
H3
|
C:I34602
|
4.7
|
10.6
|
1.0
|
|
H2
|
C:I34602
|
4.7
|
10.6
|
1.0
|
|
HG3
|
B:MET253
|
4.8
|
8.7
|
0.5
|
|
CB
|
B:THR250
|
4.8
|
8.8
|
1.0
|
|
H216
|
B:POV605
|
4.9
|
15.4
|
1.0
|
|
HE1
|
C:PHE252
|
4.9
|
7.5
|
1.0
|
|
HB2
|
B:MET253
|
4.9
|
8.7
|
0.5
|
|
HB2
|
B:MET253
|
4.9
|
8.7
|
0.5
|
|
O11
|
C:I34602
|
5.0
|
10.6
|
1.0
|
|
Chlorine binding site 6 out
of 10 in 8v8a
Go back to
Chlorine Binding Sites List in 8v8a
Chlorine binding site 6 out
of 10 in the ALPHA7-Nicotinic Acetylcholine Receptor Time Resolved Bound to Epibatidine and Pnu-120596 Desensitized Intermediate State
 Mono view
 Stereo pair view
|
|
A full contact list of Chlorine with other atoms in the Cl binding
site number 6 of ALPHA7-Nicotinic Acetylcholine Receptor Time Resolved Bound to Epibatidine and Pnu-120596 Desensitized Intermediate State within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:Cl608
b:2.2
occ:1.00
|
CL
|
C:EPJ608
|
0.0
|
2.2
|
1.0
|
|
C10
|
C:EPJ608
|
1.7
|
2.2
|
1.0
|
|
N2
|
C:EPJ608
|
2.6
|
2.2
|
1.0
|
|
C9
|
C:EPJ608
|
2.7
|
2.2
|
1.0
|
|
HB2
|
D:LEU108
|
2.8
|
0.2
|
1.0
|
|
H9
|
C:EPJ608
|
2.8
|
2.2
|
1.0
|
|
HB3
|
D:LEU108
|
3.0
|
0.2
|
1.0
|
|
H
|
D:LEU108
|
3.1
|
0.2
|
1.0
|
|
O
|
D:GLN116
|
3.1
|
0.2
|
1.0
|
|
O
|
D:HOH710
|
3.3
|
2.8
|
1.0
|
|
CB
|
D:LEU108
|
3.3
|
0.2
|
1.0
|
|
O
|
D:ASN106
|
3.4
|
0.0
|
1.0
|
|
N
|
D:LEU108
|
3.6
|
0.2
|
1.0
|
|
HD13
|
D:LEU118
|
3.6
|
0.2
|
1.0
|
|
HB2
|
C:SER149
|
3.7
|
1.1
|
1.0
|
|
H
|
D:LEU118
|
3.8
|
0.2
|
1.0
|
|
HB3
|
C:SER149
|
3.8
|
1.1
|
1.0
|
|
HB3
|
D:GLN116
|
3.8
|
0.2
|
1.0
|
|
C11
|
C:EPJ608
|
3.8
|
2.2
|
1.0
|
|
HA
|
D:TYR117
|
3.9
|
0.1
|
1.0
|
|
C
|
D:GLN116
|
3.9
|
0.2
|
1.0
|
|
HD22
|
D:LEU108
|
4.0
|
0.2
|
1.0
|
|
C8
|
C:EPJ608
|
4.0
|
2.2
|
1.0
|
|
HA
|
D:VAL107
|
4.0
|
0.1
|
1.0
|
|
HB2
|
D:LEU118
|
4.0
|
0.2
|
1.0
|
|
HB2
|
D:GLN116
|
4.1
|
0.2
|
1.0
|
|
HD23
|
D:LEU108
|
4.1
|
0.2
|
1.0
|
|
CA
|
D:LEU108
|
4.1
|
0.2
|
1.0
|
|
CB
|
C:SER149
|
4.2
|
1.1
|
1.0
|
|
HA
|
C:SER149
|
4.2
|
1.1
|
1.0
|
|
CD2
|
D:LEU108
|
4.3
|
0.2
|
1.0
|
|
C
|
D:ASN106
|
4.4
|
0.0
|
1.0
|
|
CB
|
D:GLN116
|
4.4
|
0.2
|
1.0
|
|
N
|
D:LEU118
|
4.4
|
0.2
|
1.0
|
|
C
|
D:VAL107
|
4.4
|
0.1
|
1.0
|
|
CD1
|
D:LEU118
|
4.4
|
0.2
|
1.0
|
|
C7
|
C:EPJ608
|
4.5
|
2.2
|
1.0
|
|
HD12
|
D:LEU118
|
4.5
|
0.2
|
1.0
|
|
CG
|
D:LEU108
|
4.5
|
0.2
|
1.0
|
|
H11
|
C:EPJ608
|
4.6
|
2.2
|
1.0
|
|
CA
|
D:VAL107
|
4.6
|
0.1
|
1.0
|
|
CA
|
D:TYR117
|
4.6
|
0.1
|
1.0
|
|
N
|
D:TYR117
|
4.6
|
0.1
|
1.0
|
|
HA
|
D:LEU108
|
4.6
|
0.2
|
1.0
|
|
H8
|
C:EPJ608
|
4.7
|
2.2
|
1.0
|
|
CA
|
C:SER149
|
4.7
|
1.1
|
1.0
|
|
CA
|
D:GLN116
|
4.8
|
0.2
|
1.0
|
|
CB
|
D:LEU118
|
4.9
|
0.2
|
1.0
|
|
N
|
D:VAL107
|
4.9
|
0.1
|
1.0
|
|
C
|
D:TYR117
|
4.9
|
0.1
|
1.0
|
|
HB2
|
D:ASN106
|
5.0
|
0.0
|
1.0
|
|
Chlorine binding site 7 out
of 10 in 8v8a
Go back to
Chlorine Binding Sites List in 8v8a
Chlorine binding site 7 out
of 10 in the ALPHA7-Nicotinic Acetylcholine Receptor Time Resolved Bound to Epibatidine and Pnu-120596 Desensitized Intermediate State
 Mono view
 Stereo pair view
|
|
A full contact list of Chlorine with other atoms in the Cl binding
site number 7 of ALPHA7-Nicotinic Acetylcholine Receptor Time Resolved Bound to Epibatidine and Pnu-120596 Desensitized Intermediate State within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
D:Cl602
b:10.6
occ:1.00
|
CL1
|
D:I34602
|
0.0
|
10.6
|
1.0
|
|
C20
|
D:I34602
|
1.7
|
10.6
|
1.0
|
|
HD11
|
D:ILE221
|
2.6
|
8.4
|
1.0
|
|
C19
|
D:I34602
|
2.7
|
10.6
|
1.0
|
|
C03
|
D:I34602
|
2.7
|
10.6
|
1.0
|
|
HE1
|
C:MET278
|
2.8
|
11.5
|
1.0
|
|
H12
|
D:I34602
|
2.8
|
10.6
|
1.0
|
|
HB3
|
D:PRO217
|
2.8
|
6.9
|
1.0
|
|
O02
|
D:I34602
|
2.9
|
10.6
|
1.0
|
|
H21J
|
C:POV605
|
2.9
|
15.4
|
1.0
|
|
HG22
|
C:THR250
|
3.1
|
8.8
|
1.0
|
|
HE2
|
C:MET278
|
3.4
|
11.5
|
1.0
|
|
CE
|
C:MET278
|
3.4
|
11.5
|
1.0
|
|
CD1
|
D:ILE221
|
3.5
|
8.4
|
1.0
|
|
HZ
|
D:PHE252
|
3.5
|
7.5
|
1.0
|
|
H21F
|
C:POV605
|
3.5
|
15.4
|
1.0
|
|
HD12
|
D:ILE221
|
3.6
|
8.4
|
1.0
|
|
CB
|
D:PRO217
|
3.8
|
6.9
|
1.0
|
|
C218
|
C:POV605
|
3.8
|
15.4
|
1.0
|
|
SD
|
C:MET278
|
3.9
|
11.5
|
1.0
|
|
HD13
|
D:ILE221
|
4.0
|
8.4
|
1.0
|
|
C08
|
D:I34602
|
4.0
|
10.6
|
1.0
|
|
C04
|
D:I34602
|
4.0
|
10.6
|
1.0
|
|
CG2
|
C:THR250
|
4.0
|
8.8
|
1.0
|
|
HB2
|
D:PRO217
|
4.0
|
6.9
|
1.0
|
|
H21H
|
C:POV605
|
4.2
|
15.4
|
1.0
|
|
HG21
|
C:THR250
|
4.2
|
8.8
|
1.0
|
|
HE3
|
C:MET278
|
4.3
|
11.5
|
1.0
|
|
C01
|
D:I34602
|
4.3
|
10.6
|
1.0
|
|
HG13
|
D:ILE221
|
4.3
|
8.4
|
1.0
|
|
C216
|
C:POV605
|
4.4
|
15.4
|
1.0
|
|
HG3
|
D:PRO217
|
4.4
|
6.9
|
1.0
|
|
CZ
|
D:PHE252
|
4.4
|
7.5
|
1.0
|
|
H218
|
C:POV605
|
4.4
|
15.4
|
1.0
|
|
CG1
|
D:ILE221
|
4.5
|
8.4
|
1.0
|
|
HA
|
C:THR250
|
4.5
|
8.8
|
1.0
|
|
C05
|
D:I34602
|
4.5
|
10.6
|
1.0
|
|
C217
|
C:POV605
|
4.5
|
15.4
|
1.0
|
|
HA
|
D:PRO217
|
4.5
|
6.9
|
1.0
|
|
HG23
|
C:THR250
|
4.5
|
8.8
|
1.0
|
|
CG
|
D:PRO217
|
4.6
|
6.9
|
1.0
|
|
H217
|
C:POV605
|
4.6
|
15.4
|
1.0
|
|
HB
|
C:THR250
|
4.6
|
8.8
|
1.0
|
|
HG12
|
D:ILE221
|
4.6
|
8.4
|
1.0
|
|
H1
|
D:I34602
|
4.6
|
10.6
|
1.0
|
|
SD
|
C:MET253
|
4.7
|
8.7
|
0.5
|
|
CA
|
D:PRO217
|
4.7
|
6.9
|
1.0
|
|
HG2
|
D:PRO217
|
4.7
|
6.9
|
1.0
|
|
H4
|
D:I34602
|
4.7
|
10.6
|
1.0
|
|
H3
|
D:I34602
|
4.7
|
10.6
|
1.0
|
|
H2
|
D:I34602
|
4.7
|
10.6
|
1.0
|
|
HG3
|
C:MET253
|
4.8
|
8.7
|
0.5
|
|
CB
|
C:THR250
|
4.8
|
8.8
|
1.0
|
|
H216
|
C:POV605
|
4.9
|
15.4
|
1.0
|
|
HE1
|
D:PHE252
|
4.9
|
7.5
|
1.0
|
|
HB2
|
C:MET253
|
4.9
|
8.7
|
0.5
|
|
HB2
|
C:MET253
|
4.9
|
8.7
|
0.5
|
|
O11
|
D:I34602
|
5.0
|
10.6
|
1.0
|
|
Chlorine binding site 8 out
of 10 in 8v8a
Go back to
Chlorine Binding Sites List in 8v8a
Chlorine binding site 8 out
of 10 in the ALPHA7-Nicotinic Acetylcholine Receptor Time Resolved Bound to Epibatidine and Pnu-120596 Desensitized Intermediate State
 Mono view
 Stereo pair view
|
|
A full contact list of Chlorine with other atoms in the Cl binding
site number 8 of ALPHA7-Nicotinic Acetylcholine Receptor Time Resolved Bound to Epibatidine and Pnu-120596 Desensitized Intermediate State within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
D:Cl608
b:2.2
occ:1.00
|
CL
|
D:EPJ608
|
0.0
|
2.2
|
1.0
|
|
C10
|
D:EPJ608
|
1.7
|
2.2
|
1.0
|
|
N2
|
D:EPJ608
|
2.6
|
2.2
|
1.0
|
|
C9
|
D:EPJ608
|
2.7
|
2.2
|
1.0
|
|
HB2
|
E:LEU108
|
2.8
|
0.2
|
1.0
|
|
H9
|
D:EPJ608
|
2.8
|
2.2
|
1.0
|
|
HB3
|
E:LEU108
|
3.0
|
0.2
|
1.0
|
|
H
|
E:LEU108
|
3.1
|
0.2
|
1.0
|
|
O
|
E:GLN116
|
3.1
|
0.2
|
1.0
|
|
O
|
E:HOH710
|
3.3
|
2.8
|
1.0
|
|
CB
|
E:LEU108
|
3.3
|
0.2
|
1.0
|
|
O
|
E:ASN106
|
3.4
|
0.0
|
1.0
|
|
HD13
|
E:LEU118
|
3.6
|
0.2
|
1.0
|
|
N
|
E:LEU108
|
3.6
|
0.2
|
1.0
|
|
HB2
|
D:SER149
|
3.7
|
1.1
|
1.0
|
|
H
|
E:LEU118
|
3.8
|
0.2
|
1.0
|
|
HB3
|
D:SER149
|
3.8
|
1.1
|
1.0
|
|
HB3
|
E:GLN116
|
3.8
|
0.2
|
1.0
|
|
C11
|
D:EPJ608
|
3.8
|
2.2
|
1.0
|
|
HA
|
E:TYR117
|
3.9
|
0.1
|
1.0
|
|
C
|
E:GLN116
|
3.9
|
0.2
|
1.0
|
|
HD22
|
E:LEU108
|
4.0
|
0.2
|
1.0
|
|
C8
|
D:EPJ608
|
4.0
|
2.2
|
1.0
|
|
HA
|
E:VAL107
|
4.0
|
0.1
|
1.0
|
|
HB2
|
E:LEU118
|
4.0
|
0.2
|
1.0
|
|
HB2
|
E:GLN116
|
4.1
|
0.2
|
1.0
|
|
HD23
|
E:LEU108
|
4.1
|
0.2
|
1.0
|
|
CA
|
E:LEU108
|
4.1
|
0.2
|
1.0
|
|
CB
|
D:SER149
|
4.2
|
1.1
|
1.0
|
|
HA
|
D:SER149
|
4.2
|
1.1
|
1.0
|
|
CD2
|
E:LEU108
|
4.3
|
0.2
|
1.0
|
|
CB
|
E:GLN116
|
4.4
|
0.2
|
1.0
|
|
C
|
E:ASN106
|
4.4
|
0.0
|
1.0
|
|
N
|
E:LEU118
|
4.4
|
0.2
|
1.0
|
|
C
|
E:VAL107
|
4.4
|
0.1
|
1.0
|
|
CD1
|
E:LEU118
|
4.4
|
0.2
|
1.0
|
|
C7
|
D:EPJ608
|
4.5
|
2.2
|
1.0
|
|
HD12
|
E:LEU118
|
4.5
|
0.2
|
1.0
|
|
CG
|
E:LEU108
|
4.5
|
0.2
|
1.0
|
|
H11
|
D:EPJ608
|
4.6
|
2.2
|
1.0
|
|
CA
|
E:TYR117
|
4.6
|
0.1
|
1.0
|
|
CA
|
E:VAL107
|
4.6
|
0.1
|
1.0
|
|
N
|
E:TYR117
|
4.6
|
0.1
|
1.0
|
|
HA
|
E:LEU108
|
4.6
|
0.2
|
1.0
|
|
H8
|
D:EPJ608
|
4.7
|
2.2
|
1.0
|
|
CA
|
D:SER149
|
4.7
|
1.1
|
1.0
|
|
CA
|
E:GLN116
|
4.8
|
0.2
|
1.0
|
|
CB
|
E:LEU118
|
4.9
|
0.2
|
1.0
|
|
N
|
E:VAL107
|
4.9
|
0.1
|
1.0
|
|
C
|
E:TYR117
|
4.9
|
0.1
|
1.0
|
|
HB2
|
E:ASN106
|
5.0
|
0.0
|
1.0
|
|
Chlorine binding site 9 out
of 10 in 8v8a
Go back to
Chlorine Binding Sites List in 8v8a
Chlorine binding site 9 out
of 10 in the ALPHA7-Nicotinic Acetylcholine Receptor Time Resolved Bound to Epibatidine and Pnu-120596 Desensitized Intermediate State
 Mono view
 Stereo pair view
|
|
A full contact list of Chlorine with other atoms in the Cl binding
site number 9 of ALPHA7-Nicotinic Acetylcholine Receptor Time Resolved Bound to Epibatidine and Pnu-120596 Desensitized Intermediate State within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
E:Cl602
b:10.6
occ:1.00
|
CL1
|
E:I34602
|
0.0
|
10.6
|
1.0
|
|
C20
|
E:I34602
|
1.7
|
10.6
|
1.0
|
|
HD11
|
E:ILE221
|
2.6
|
8.4
|
1.0
|
|
C19
|
E:I34602
|
2.7
|
10.6
|
1.0
|
|
C03
|
E:I34602
|
2.7
|
10.6
|
1.0
|
|
HE1
|
D:MET278
|
2.8
|
11.5
|
1.0
|
|
H12
|
E:I34602
|
2.8
|
10.6
|
1.0
|
|
HB3
|
E:PRO217
|
2.8
|
6.9
|
1.0
|
|
O02
|
E:I34602
|
2.9
|
10.6
|
1.0
|
|
H21J
|
D:POV605
|
2.9
|
15.4
|
1.0
|
|
HG22
|
D:THR250
|
3.1
|
8.8
|
1.0
|
|
HE2
|
D:MET278
|
3.4
|
11.5
|
1.0
|
|
CE
|
D:MET278
|
3.4
|
11.5
|
1.0
|
|
CD1
|
E:ILE221
|
3.5
|
8.4
|
1.0
|
|
H21F
|
D:POV605
|
3.5
|
15.4
|
1.0
|
|
HZ
|
E:PHE252
|
3.5
|
7.5
|
1.0
|
|
HD12
|
E:ILE221
|
3.6
|
8.4
|
1.0
|
|
CB
|
E:PRO217
|
3.8
|
6.9
|
1.0
|
|
C218
|
D:POV605
|
3.8
|
15.4
|
1.0
|
|
SD
|
D:MET278
|
3.9
|
11.5
|
1.0
|
|
HD13
|
E:ILE221
|
4.0
|
8.4
|
1.0
|
|
C08
|
E:I34602
|
4.0
|
10.6
|
1.0
|
|
C04
|
E:I34602
|
4.0
|
10.6
|
1.0
|
|
CG2
|
D:THR250
|
4.0
|
8.8
|
1.0
|
|
HB2
|
E:PRO217
|
4.0
|
6.9
|
1.0
|
|
H21H
|
D:POV605
|
4.2
|
15.4
|
1.0
|
|
HG21
|
D:THR250
|
4.2
|
8.8
|
1.0
|
|
HE3
|
D:MET278
|
4.3
|
11.5
|
1.0
|
|
C01
|
E:I34602
|
4.3
|
10.6
|
1.0
|
|
HG13
|
E:ILE221
|
4.3
|
8.4
|
1.0
|
|
C216
|
D:POV605
|
4.4
|
15.4
|
1.0
|
|
HG3
|
E:PRO217
|
4.4
|
6.9
|
1.0
|
|
H218
|
D:POV605
|
4.4
|
15.4
|
1.0
|
|
CZ
|
E:PHE252
|
4.4
|
7.5
|
1.0
|
|
CG1
|
E:ILE221
|
4.5
|
8.4
|
1.0
|
|
HA
|
D:THR250
|
4.5
|
8.8
|
1.0
|
|
C05
|
E:I34602
|
4.5
|
10.6
|
1.0
|
|
C217
|
D:POV605
|
4.5
|
15.4
|
1.0
|
|
HA
|
E:PRO217
|
4.5
|
6.9
|
1.0
|
|
HG23
|
D:THR250
|
4.5
|
8.8
|
1.0
|
|
CG
|
E:PRO217
|
4.6
|
6.9
|
1.0
|
|
H217
|
D:POV605
|
4.6
|
15.4
|
1.0
|
|
HB
|
D:THR250
|
4.6
|
8.8
|
1.0
|
|
HG12
|
E:ILE221
|
4.6
|
8.4
|
1.0
|
|
H1
|
E:I34602
|
4.6
|
10.6
|
1.0
|
|
SD
|
D:MET253
|
4.7
|
8.7
|
0.5
|
|
CA
|
E:PRO217
|
4.7
|
6.9
|
1.0
|
|
HG2
|
E:PRO217
|
4.7
|
6.9
|
1.0
|
|
H4
|
E:I34602
|
4.7
|
10.6
|
1.0
|
|
H3
|
E:I34602
|
4.7
|
10.6
|
1.0
|
|
H2
|
E:I34602
|
4.7
|
10.6
|
1.0
|
|
HG3
|
D:MET253
|
4.8
|
8.7
|
0.5
|
|
CB
|
D:THR250
|
4.8
|
8.8
|
1.0
|
|
H216
|
D:POV605
|
4.9
|
15.4
|
1.0
|
|
HB2
|
D:MET253
|
4.9
|
8.7
|
0.5
|
|
HE1
|
E:PHE252
|
4.9
|
7.5
|
1.0
|
|
HB2
|
D:MET253
|
4.9
|
8.7
|
0.5
|
|
O11
|
E:I34602
|
5.0
|
10.6
|
1.0
|
|
Chlorine binding site 10 out
of 10 in 8v8a
Go back to
Chlorine Binding Sites List in 8v8a
Chlorine binding site 10 out
of 10 in the ALPHA7-Nicotinic Acetylcholine Receptor Time Resolved Bound to Epibatidine and Pnu-120596 Desensitized Intermediate State
 Mono view
 Stereo pair view
|
|
A full contact list of Chlorine with other atoms in the Cl binding
site number 10 of ALPHA7-Nicotinic Acetylcholine Receptor Time Resolved Bound to Epibatidine and Pnu-120596 Desensitized Intermediate State within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
E:Cl608
b:2.2
occ:1.00
|
CL
|
E:EPJ608
|
0.0
|
2.2
|
1.0
|
|
C10
|
E:EPJ608
|
1.7
|
2.2
|
1.0
|
|
N2
|
E:EPJ608
|
2.6
|
2.2
|
1.0
|
|
C9
|
E:EPJ608
|
2.7
|
2.2
|
1.0
|
|
HB2
|
A:LEU108
|
2.8
|
0.2
|
1.0
|
|
H9
|
E:EPJ608
|
2.8
|
2.2
|
1.0
|
|
HB3
|
A:LEU108
|
3.0
|
0.2
|
1.0
|
|
H
|
A:LEU108
|
3.1
|
0.2
|
1.0
|
|
O
|
A:GLN116
|
3.1
|
0.2
|
1.0
|
|
O
|
A:HOH710
|
3.3
|
2.8
|
1.0
|
|
CB
|
A:LEU108
|
3.3
|
0.2
|
1.0
|
|
O
|
A:ASN106
|
3.4
|
0.0
|
1.0
|
|
HD13
|
A:LEU118
|
3.6
|
0.2
|
1.0
|
|
N
|
A:LEU108
|
3.6
|
0.2
|
1.0
|
|
HB2
|
E:SER149
|
3.7
|
1.1
|
1.0
|
|
H
|
A:LEU118
|
3.8
|
0.2
|
1.0
|
|
HB3
|
E:SER149
|
3.8
|
1.1
|
1.0
|
|
HB3
|
A:GLN116
|
3.8
|
0.2
|
1.0
|
|
C11
|
E:EPJ608
|
3.8
|
2.2
|
1.0
|
|
HA
|
A:TYR117
|
3.9
|
0.1
|
1.0
|
|
C
|
A:GLN116
|
3.9
|
0.2
|
1.0
|
|
HD22
|
A:LEU108
|
3.9
|
0.2
|
1.0
|
|
C8
|
E:EPJ608
|
4.0
|
2.2
|
1.0
|
|
HA
|
A:VAL107
|
4.0
|
0.1
|
1.0
|
|
HB2
|
A:LEU118
|
4.0
|
0.2
|
1.0
|
|
HD23
|
A:LEU108
|
4.0
|
0.2
|
1.0
|
|
HB2
|
A:GLN116
|
4.0
|
0.2
|
1.0
|
|
CA
|
A:LEU108
|
4.1
|
0.2
|
1.0
|
|
CB
|
E:SER149
|
4.2
|
1.1
|
1.0
|
|
HA
|
E:SER149
|
4.2
|
1.1
|
1.0
|
|
CD2
|
A:LEU108
|
4.3
|
0.2
|
1.0
|
|
CB
|
A:GLN116
|
4.4
|
0.2
|
1.0
|
|
C
|
A:ASN106
|
4.4
|
0.0
|
1.0
|
|
C
|
A:VAL107
|
4.4
|
0.1
|
1.0
|
|
N
|
A:LEU118
|
4.4
|
0.2
|
1.0
|
|
CD1
|
A:LEU118
|
4.4
|
0.2
|
1.0
|
|
C7
|
E:EPJ608
|
4.5
|
2.2
|
1.0
|
|
CG
|
A:LEU108
|
4.5
|
0.2
|
1.0
|
|
HD12
|
A:LEU118
|
4.5
|
0.2
|
1.0
|
|
H11
|
E:EPJ608
|
4.6
|
2.2
|
1.0
|
|
CA
|
A:VAL107
|
4.6
|
0.1
|
1.0
|
|
CA
|
A:TYR117
|
4.6
|
0.1
|
1.0
|
|
N
|
A:TYR117
|
4.6
|
0.1
|
1.0
|
|
HA
|
A:LEU108
|
4.6
|
0.2
|
1.0
|
|
H8
|
E:EPJ608
|
4.7
|
2.2
|
1.0
|
|
CA
|
E:SER149
|
4.7
|
1.1
|
1.0
|
|
CA
|
A:GLN116
|
4.8
|
0.2
|
1.0
|
|
CB
|
A:LEU118
|
4.9
|
0.2
|
1.0
|
|
N
|
A:VAL107
|
4.9
|
0.1
|
1.0
|
|
C
|
A:TYR117
|
5.0
|
0.1
|
1.0
|
|
HB2
|
A:ASN106
|
5.0
|
0.0
|
1.0
|
|
Reference:
S.M.Burke,
M.Avstrikova,
C.M.Noviello,
N.Mukhtasimova,
J.P.Changeux,
G.A.Thakur,
S.M.Sine,
M.Cecchini,
R.E.Hibbs.
ALPHA7-Nicotinic Acetylcholine Receptor Time Resolved Bound to Epibatidine and Pnu-120596 Desensitized Intermediate State To Be Published.
Page generated: Tue Jul 30 13:32:14 2024
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