Chlorine in PDB 8vtr: Structure of FABS1CE3-Epr-1, An Elbow-Locked High Affinity Antibody For the Erythropoeitin Receptor (Orthorhombic Form)

The structure of Structure of FABS1CE3-Epr-1, An Elbow-Locked High Affinity Antibody For the Erythropoeitin Receptor (Orthorhombic Form), PDB code: 8vtr was solved by A.U.Singer, H.A.Bruce, A.Pavlenco, L.Ploder, G.Luu, L.Blazer, J.J.Adams, S.S.Sidhu, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	58.12 / 1.96
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	73.199, 74.275, 93.335, 90, 90, 90
R / Rfree (%)	18.7 / 22.8

The binding sites of Chlorine atom in the Structure of FABS1CE3-Epr-1, An Elbow-Locked High Affinity Antibody For the Erythropoeitin Receptor (Orthorhombic Form) (pdb code 8vtr). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Structure of FABS1CE3-Epr-1, An Elbow-Locked High Affinity Antibody For the Erythropoeitin Receptor (Orthorhombic Form), PDB code: 8vtr:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Structure of FABS1CE3-Epr-1, An Elbow-Locked High Affinity Antibody For the Erythropoeitin Receptor (Orthorhombic Form)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Structure of FABS1CE3-Epr-1, An Elbow-Locked High Affinity Antibody For the Erythropoeitin Receptor (Orthorhombic Form) within 5.0Å range: probe atom residue distance (Å) B Occ G:Cl307 b:69.0 occ:1.00 NE G:ARG162 3.5 47.5 1.0 NH2 G:ARG162 3.7 46.4 1.0 CZ G:ARG162 4.1 45.1 1.0 O G:HOH526 4.3 51.8 1.0 CG2 G:VAL183 4.5 40.4 1.0 CB G:VAL183 4.5 39.7 1.0 CD G:ARG162 4.6 41.9 1.0 CG1 G:VAL183 4.9 43.6 1.0

Chlorine binding site 2 out of 2 in the Structure of FABS1CE3-Epr-1, An Elbow-Locked High Affinity Antibody For the Erythropoeitin Receptor (Orthorhombic Form)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Structure of FABS1CE3-Epr-1, An Elbow-Locked High Affinity Antibody For the Erythropoeitin Receptor (Orthorhombic Form) within 5.0Å range: probe atom residue distance (Å) B Occ G:Cl308 b:76.6 occ:1.00 NH1 G:ARG229 3.5 46.2 1.0 NH2 G:ARG229 3.5 44.7 1.0 CZ G:ARG229 3.9 46.6 1.0 CE G:LYS210 4.2 68.2 1.0 CD G:LYS210 4.3 53.5 1.0 NZ G:LYS210 4.6 65.4 1.0

H.A.Bruce, A.U.Singer, L.L.Blazer, K.Luu, L.Ploder, A.Pavlenco, I.Kurinov, J.J.Adams, S.S.Sidhu. Antigen-Binding Fragments with Improved Crystal Lattice Packing and Enhanced Conformational Flexibility at the Elbow Region As Crystallization Chaperones. Protein Sci. V. 33 E5081 2024.
ISSN: ESSN 1469-896X
PubMed: 38924648
DOI: 10.1002/PRO.5081