Chlorine in PDB 8w4l: Crystal Structure of Closed Conformation of Human Immunoglobulin Fc in Presence of Endosz

The structure of Crystal Structure of Closed Conformation of Human Immunoglobulin Fc in Presence of Endosz, PDB code: 8w4l was solved by H.H.Guan, C.C.Lin, Y.C.Hsieh, C.J.Chen, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	28.72 / 3.10
Space group	P 61 2 2
Cell size a, b, c (Å), α, β, γ (°)	151.964, 151.964, 113.3, 90, 90, 120
R / Rfree (%)	20.7 / 25.7

The binding sites of Chlorine atom in the Crystal Structure of Closed Conformation of Human Immunoglobulin Fc in Presence of Endosz (pdb code 8w4l). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Crystal Structure of Closed Conformation of Human Immunoglobulin Fc in Presence of Endosz, PDB code: 8w4l:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Crystal Structure of Closed Conformation of Human Immunoglobulin Fc in Presence of Endosz


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Closed Conformation of Human Immunoglobulin Fc in Presence of Endosz within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl501 b:57.0 occ:1.00 OE1 A:GLN311 3.0 59.3 1.0 CD A:GLN311 3.9 54.5 1.0 CB A:LEU309 3.9 49.6 1.0 N A:HIS310 4.1 45.1 1.0 CA A:LEU309 4.1 45.5 1.0 NE2 A:GLN311 4.3 57.6 1.0 CD2 A:LEU309 4.3 42.6 1.0 CG A:LEU309 4.5 46.9 1.0 C A:LEU309 4.6 44.6 1.0 CD1 A:LEU309 4.6 43.6 1.0 ND1 A:HIS310 4.7 44.9 1.0 CB A:HIS310 4.9 40.6 1.0 CG A:GLN311 5.0 49.3 1.0

Chlorine binding site 2 out of 2 in the Crystal Structure of Closed Conformation of Human Immunoglobulin Fc in Presence of Endosz


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of Closed Conformation of Human Immunoglobulin Fc in Presence of Endosz within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl501 b:59.4 occ:1.00 OE1 B:GLN311 3.6 21.6 1.0 NE2 B:GLN311 3.6 21.6 1.0 N B:HIS310 3.8 21.2 1.0 CB B:LEU309 3.9 19.9 1.0 CD B:GLN311 4.0 21.2 1.0 CA B:LEU309 4.0 15.9 1.0 CD2 B:LEU309 4.2 9.9 1.0 CG B:LEU309 4.4 13.9 1.0 C B:LEU309 4.4 18.3 1.0 CD1 B:LEU309 4.4 11.0 1.0 ND1 B:HIS310 4.4 24.6 1.0 CB B:HIS310 4.8 21.8 1.0 CA B:HIS310 4.9 22.1 1.0

Y.C.Hsieh, H.H.Guan, C.C.Lin, T.Y.Huang, P.Chuankhayan, N.C.Chen, N.H.Wang, P.L.Hu, Y.C.Tsai, Y.C.Huang, M.Yoshimura, P.J.Lin, Y.H.Hsieh, C.J.Chen. Structure-Based High-Efficiency Homogeneous Antibody Platform By Endoglycosidase Sz Provides Insights Into Its Transglycosylation Mechanism Jacs Au V. 4 2130 2024.
ISSN: ESSN 2691-3704
DOI: 10.1021/JACSAU.4C00004