Chlorine in PDB 8wvb: Crystal Structure of LSD18 Mutant S195M

The structure of Crystal Structure of LSD18 Mutant S195M, PDB code: 8wvb was solved by N.Liu, H.L.Xiao, X.Chen, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	30.11 / 2.50
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	62.041, 48.671, 136.049, 90, 91.34, 90
R / Rfree (%)	20.9 / 25.2

The binding sites of Chlorine atom in the Crystal Structure of LSD18 Mutant S195M (pdb code 8wvb). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Crystal Structure of LSD18 Mutant S195M, PDB code: 8wvb:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Crystal Structure of LSD18 Mutant S195M


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of LSD18 Mutant S195M within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl702 b:18.6 occ:1.00 OG A:SER309 2.8 10.0 1.0 CB A:SER309 3.5 12.4 1.0 OG A:SER311 3.8 12.8 1.0 CA A:GLN66 3.8 10.9 1.0 N A:GLN66 3.9 11.8 1.0 C A:PRO65 4.0 15.6 1.0 O A:PRO65 4.1 22.2 1.0 C8M A:FAD701 4.2 10.0 1.0 CB A:GLN66 4.2 13.2 1.0 CB A:PRO65 4.3 13.9 1.0 CG A:PRO65 4.4 11.1 1.0 CD2 A:HIS69 4.4 15.4 1.0 NE2 A:HIS69 4.4 14.2 1.0 CA A:SER309 4.5 12.8 1.0 CB A:SER311 4.5 12.8 1.0 C7M A:FAD701 4.7 10.0 1.0 OE1 A:GLN66 4.8 11.2 1.0 CA A:PRO65 4.8 13.6 1.0

Chlorine binding site 2 out of 2 in the Crystal Structure of LSD18 Mutant S195M


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of LSD18 Mutant S195M within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl702 b:25.0 occ:1.00 OG B:SER309 3.3 22.0 1.0 CB B:SER309 3.6 18.2 1.0 CA B:GLN66 3.7 12.3 1.0 OG B:SER311 3.7 34.2 1.0 N B:GLN66 3.8 12.4 1.0 O B:PRO65 4.0 14.8 1.0 C B:PRO65 4.0 17.1 1.0 CB B:GLN66 4.0 12.1 1.0 C8M B:FAD701 4.1 12.2 1.0 CD2 B:HIS69 4.1 19.5 1.0 NE2 B:HIS69 4.2 19.1 1.0 CB B:PRO65 4.5 15.9 1.0 CG B:PRO65 4.6 18.2 1.0 CB B:SER311 4.7 29.5 1.0 C7M B:FAD701 4.7 14.1 1.0 CA B:SER309 4.7 13.1 1.0 CA B:PRO65 4.9 17.0 1.0 C B:GLN66 5.0 12.1 1.0

N.Liu, H.Xiao, Y.Zang, L.Zhou, J.Mencius, Z.Yang, S.Quan, X.Chen. Simultaneous Improvement in the Thermostability and Catalytic Activity of Epoxidase LSD18 For the Synthesis of Lasalocid A Int J Mol Sci V. 24 2023.
ISSN: ESSN 1422-0067
DOI: 10.3390/IJMS242316795