Chlorine in PDB 9axf: Structure of Human Calcium-Sensing Receptor in Complex with Chimeric Gq (Minigisq) Protein in Detergent

The structure of Structure of Human Calcium-Sensing Receptor in Complex with Chimeric Gq (Minigisq) Protein in Detergent also contains other interesting chemical elements:

Calcium

(Ca)

7 atoms

The binding sites of Chlorine atom in the Structure of Human Calcium-Sensing Receptor in Complex with Chimeric Gq (Minigisq) Protein in Detergent (pdb code 9axf). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Structure of Human Calcium-Sensing Receptor in Complex with Chimeric Gq (Minigisq) Protein in Detergent, PDB code: 9axf:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Structure of Human Calcium-Sensing Receptor in Complex with Chimeric Gq (Minigisq) Protein in Detergent


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Structure of Human Calcium-Sensing Receptor in Complex with Chimeric Gq (Minigisq) Protein in Detergent within 5.0Å range: probe atom residue distance (Å) B Occ R:Cl1010 b:35.1 occ:1.00 CL21 R:9IG1010 0.0 35.1 1.0 C20 R:9IG1010 1.7 35.1 1.0 C19 R:9IG1010 2.6 35.1 1.0 C15 R:9IG1010 2.7 35.1 1.0 C14 R:9IG1010 3.1 35.1 1.0 C04 R:9IG1010 3.4 35.1 1.0 CZ3 R:TRP818 3.6 27.5 1.0 CE3 R:TRP818 3.7 27.5 1.0 O09 R:9IG1010 3.7 35.1 1.0 CH2 R:TRP818 3.9 27.5 1.0 C13 R:9IG1010 3.9 35.1 1.0 C18 R:9IG1010 3.9 35.1 1.0 CD2 R:TRP818 4.0 27.5 1.0 C16 R:9IG1010 4.0 35.1 1.0 C05 R:9IG1010 4.1 35.1 1.0 CZ2 R:TRP818 4.1 27.5 1.0 CE2 R:TRP818 4.2 27.5 1.0 C10 R:9IG1010 4.4 35.1 1.0 C17 R:9IG1010 4.5 35.1 1.0 CAT R:Y011014 4.5 41.1 1.0 C03 R:9IG1010 4.5 35.1 1.0 C02 R:9IG1010 4.6 35.1 1.0 CG R:TRP818 4.8 27.5 1.0 CAS R:Y011014 4.8 41.1 1.0 C12 R:9IG1010 4.8 35.1 1.0 CAR R:Y011014 5.0 41.1 1.0 NE1 R:TRP818 5.0 27.5 1.0

Chlorine binding site 2 out of 2 in the Structure of Human Calcium-Sensing Receptor in Complex with Chimeric Gq (Minigisq) Protein in Detergent


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Structure of Human Calcium-Sensing Receptor in Complex with Chimeric Gq (Minigisq) Protein in Detergent within 5.0Å range: probe atom residue distance (Å) B Occ Q:Cl1011 b:33.5 occ:1.00 CL21 Q:9IG1011 0.0 33.5 1.0 C20 Q:9IG1011 1.7 33.5 1.0 C19 Q:9IG1011 2.6 33.5 1.0 C15 Q:9IG1011 2.7 33.5 1.0 OH Q:TYR825 3.1 27.3 1.0 C14 Q:9IG1011 3.1 33.5 1.0 OE2 Q:GLU837 3.3 27.0 1.0 CZ Q:TYR825 3.6 27.3 1.0 OE2 Q:GLU767 3.9 47.8 1.0 C18 Q:9IG1011 3.9 33.5 1.0 C16 Q:9IG1011 4.0 33.5 1.0 CE2 Q:TYR825 4.0 27.3 1.0 CE1 Q:TYR825 4.2 27.3 1.0 CD Q:GLU767 4.4 47.8 1.0 CD Q:GLU837 4.4 27.0 1.0 C17 Q:9IG1011 4.5 33.5 1.0 OE1 Q:GLU767 4.6 47.8 1.0 C13 Q:9IG1011 4.6 33.5 1.0 NE2 Q:GLN681 4.7 31.0 1.0 CD2 Q:LEU773 4.7 39.6 1.0 OE1 Q:GLU837 4.9 27.0 1.0 CD2 Q:TYR825 5.0 27.3 1.0

H.Zuo, J.Park, A.Frangaj, J.Ye, G.Lu, J.J.Manning, W.B.Asher, Z.Lu, G.Hu, L.Wang, J.Mendez, E.Eng, Z.Zhang, X.Lin, R.Grasucci, W.A.Hendrickson, O.B.Clarke, J.A.Javitch, A.D.Conigrave, Q.R.Fan. Promiscuous G-Protein Activation By the Calcium-Sensing Receptor Nature 2024.
ISSN: ESSN 1476-4687
DOI: 10.1038/S41586-024-07331-1