Chlorine in PDB 9bcq: Extracellular Domain of Gc-A Bound to Anp

All present enzymatic activity of Extracellular Domain of Gc-A Bound to Anp:
4.6.1.2;

The binding sites of Chlorine atom in the Extracellular Domain of Gc-A Bound to Anp (pdb code 9bcq). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Extracellular Domain of Gc-A Bound to Anp, PDB code: 9bcq:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Extracellular Domain of Gc-A Bound to Anp


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Extracellular Domain of Gc-A Bound to Anp within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1101 b:29.1 occ:1.00 HG A:SER53 2.1 26.4 1.0 H A:GLY85 2.5 24.6 1.0 HD3 A:PRO10 2.6 25.7 1.0 OG A:SER53 2.9 26.4 1.0 HB3 A:PRO84 2.9 24.1 1.0 H A:CYS86 3.0 27.9 1.0 HA A:PRO84 3.3 24.1 1.0 HA A:LEU9 3.3 25.3 1.0 HB2 A:CYS60 3.4 28.0 1.0 N A:GLY85 3.4 24.6 1.0 HG3 A:PRO10 3.5 25.7 1.0 CD A:PRO10 3.6 25.7 1.0 HB2 A:SER53 3.7 26.4 1.0 HD1 A:TRP18 3.7 25.8 1.0 HD23 A:LEU9 3.7 25.3 1.0 CB A:PRO84 3.7 24.1 1.0 CB A:SER53 3.8 26.4 1.0 CA A:PRO84 3.8 24.1 1.0 HB2 A:CYS86 3.8 27.9 1.0 N A:CYS86 3.8 27.9 1.0 HE1 A:TRP18 3.9 25.8 1.0 HB3 A:ALA89 3.9 25.1 1.0 CG A:PRO10 4.0 25.7 1.0 HB3 A:CYS60 4.0 28.0 1.0 HB3 A:SER53 4.0 26.4 1.0 SG A:CYS86 4.1 27.9 1.0 O A:VAL8 4.1 24.8 1.0 CB A:CYS60 4.1 28.0 1.0 C A:PRO84 4.1 24.1 1.0 CD1 A:TRP18 4.2 25.8 1.0 CA A:LEU9 4.2 25.3 1.0 HB2 A:PRO84 4.2 24.1 1.0 HD2 A:PRO10 4.2 25.7 1.0 NE1 A:TRP18 4.3 25.8 1.0 N A:PRO10 4.3 25.7 1.0 CA A:GLY85 4.3 24.6 1.0 HB1 A:ALA89 4.3 25.1 1.0 HG2 A:PRO10 4.3 25.7 1.0 CB A:CYS86 4.4 27.9 1.0 HA3 A:GLY85 4.4 24.6 1.0 CB A:ALA89 4.5 25.1 1.0 C A:LEU9 4.6 25.3 1.0 CD2 A:LEU9 4.6 25.3 1.0 HD22 A:LEU9 4.6 25.3 1.0 C A:GLY85 4.6 24.6 1.0 HB2 A:ALA89 4.6 25.1 1.0 HG3 A:PRO84 4.7 24.1 1.0 CA A:CYS86 4.7 27.9 1.0 HG12 A:VAL8 4.8 24.8 1.0 O A:SER53 4.8 26.4 1.0 CG A:PRO84 4.8 24.1 1.0 C A:VAL8 4.8 24.8 1.0 N A:LEU9 4.9 25.3 1.0 SG A:CYS60 4.9 28.0 1.0

Chlorine binding site 2 out of 2 in the Extracellular Domain of Gc-A Bound to Anp


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Extracellular Domain of Gc-A Bound to Anp within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl1101 b:29.3 occ:1.00 HG B:SER53 1.9 26.5 1.0 OG B:SER53 2.7 26.5 1.0 HD3 B:PRO10 2.7 26.5 1.0 H B:GLY85 2.7 26.7 1.0 HB3 B:PRO84 3.0 26.1 1.0 H B:CYS86 3.0 29.2 1.0 HG3 B:PRO10 3.2 26.5 1.0 SG B:CYS60 3.3 31.7 1.0 HA B:LEU9 3.3 26.0 1.0 HA B:PRO84 3.5 26.1 1.0 CD B:PRO10 3.5 26.5 1.0 N B:GLY85 3.5 26.7 1.0 HB2 B:CYS86 3.7 29.2 1.0 CB B:SER53 3.7 26.5 1.0 CB B:PRO84 3.8 26.1 1.0 CG B:PRO10 3.8 26.5 1.0 HB2 B:SER53 3.8 26.5 1.0 HD1 B:TRP18 3.8 27.7 1.0 HB3 B:SER53 3.9 26.5 1.0 HD23 B:LEU9 3.9 26.0 1.0 N B:CYS86 3.9 29.2 1.0 CA B:PRO84 4.0 26.1 1.0 HB3 B:ALA89 4.0 26.4 1.0 HB2 B:PRO84 4.1 26.1 1.0 SG B:CYS86 4.1 29.2 1.0 HE1 B:TRP18 4.1 27.7 1.0 HG2 B:PRO10 4.2 26.5 1.0 CA B:LEU9 4.2 26.0 1.0 N B:PRO10 4.2 26.5 1.0 HD2 B:PRO10 4.2 26.5 1.0 CB B:CYS86 4.3 29.2 1.0 C B:PRO84 4.3 26.1 1.0 O B:VAL8 4.4 25.7 1.0 CD1 B:TRP18 4.4 27.7 1.0 HB1 B:ALA89 4.5 26.4 1.0 CA B:GLY85 4.5 26.7 1.0 C B:LEU9 4.5 26.0 1.0 HA3 B:GLY85 4.5 26.7 1.0 NE1 B:TRP18 4.5 27.7 1.0 CB B:ALA89 4.6 26.4 1.0 O B:SER53 4.6 26.5 1.0 CB B:CYS60 4.7 31.7 1.0 C B:GLY85 4.7 26.7 1.0 HA B:CYS60 4.7 31.7 1.0 HB3 B:CYS60 4.7 31.7 1.0 CA B:CYS86 4.7 29.2 1.0 HB2 B:ALA89 4.8 26.4 1.0 CD2 B:LEU9 4.8 26.0 1.0 HG12 B:VAL8 4.9 25.7 1.0 HG3 B:PRO84 4.9 26.1 1.0 CG B:PRO84 5.0 26.1 1.0

S.Liu, A.M.Payne, J.Wang, L.Zhu, N.Paknejad, E.T.Eng, W.Liu, Y.Miao, R.K.Hite, X.Y.Huang. Architecture and Activation of Single-Pass Transmembrane Receptor Guanylyl Cyclase. Nat.Struct.Mol.Biol. 2024.
ISSN: ESSN 1545-9985
PubMed: 39543315
DOI: 10.1038/S41594-024-01426-Z