Chlorine in PDB 9c4g: Cutibacterium Acnes 50S Ribosomal Subunit with Clindamycin Bound

The structure of Cutibacterium Acnes 50S Ribosomal Subunit with Clindamycin Bound also contains other interesting chemical elements:

Magnesium	(Mg)	247 atoms
Zinc	(Zn)	4 atoms

The binding sites of Chlorine atom in the Cutibacterium Acnes 50S Ribosomal Subunit with Clindamycin Bound (pdb code 9c4g). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Cutibacterium Acnes 50S Ribosomal Subunit with Clindamycin Bound, PDB code: 9c4g:

Chlorine binding site 1 out of 1 in the Cutibacterium Acnes 50S Ribosomal Subunit with Clindamycin Bound


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Cutibacterium Acnes 50S Ribosomal Subunit with Clindamycin Bound within 5.0Å range: probe atom residue distance (Å) B Occ a:Cl3342 b:43.4 occ:1.00 CL1 a:CLY3342 0.0 43.4 1.0 C8 a:CLY3342 1.8 29.1 1.0 C9 a:CLY3342 2.7 21.7 1.0 C7 a:CLY3342 2.7 28.9 1.0 N1 a:CLY3342 3.1 28.0 1.0 C4 a:CLY3342 3.1 29.9 1.0 O4 a:U2688 3.3 35.6 1.0 O5 a:CLY3342 3.6 30.1 1.0 C6 a:CLY3342 3.7 29.9 1.0 C4 a:U2688 3.8 33.7 1.0 C1' a:G2687 4.0 26.9 1.0 C10 a:CLY3342 4.2 26.3 1.0 O4' a:G2687 4.2 29.6 1.0 N3 a:U2688 4.3 40.3 1.0 S1 a:CLY3342 4.3 31.9 1.0 N3 a:G2687 4.4 28.3 1.0 C5 a:U2688 4.5 31.0 1.0 C5 a:CLY3342 4.5 28.9 1.0 C3 a:CLY3342 4.6 28.8 1.0 O2' a:G2687 4.6 31.1 1.0 N9 a:G2687 4.7 27.1 1.0 C12 a:CLY3342 4.8 27.3 1.0 O8 a:CLY3342 4.8 31.1 1.0 C4 a:G2687 4.9 26.8 1.0 C2' a:G2687 4.9 27.5 1.0

I.B.Lomakin, S.C.Devarkar, A.Grada, C.G.Bunick. Mechanistic Basis For the Translation Inhibition of Cutibacterium Acnes By Clindamycin. J Invest Dermatol. 2024.
ISSN: ESSN 1523-1747
PubMed: 39122144
DOI: 10.1016/J.JID.2024.07.013