Atomistry » Chlorine » PDB 7qzr-7r8s » 7qzr
Atomistry »
  Chlorine »
    PDB 7qzr-7r8s »
      7qzr »

Chlorine in PDB 7qzr: Structure of Native Leukocyte Myeloperoxidase in Complex with the Staphyloccal Peroxidase Inhibitor Spin From Staphylococcus Aureus

Protein crystallography data

The structure of Structure of Native Leukocyte Myeloperoxidase in Complex with the Staphyloccal Peroxidase Inhibitor Spin From Staphylococcus Aureus, PDB code: 7qzr was solved by V.Pfanzagl, J.A.Brito, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 19.81 / 2.18
Space group P 43 21 2
Cell size a, b, c (Å), α, β, γ (°) 112.085, 112.085, 249.949, 90, 90, 90
R / Rfree (%) 20.4 / 24.4

Other elements in 7qzr:

The structure of Structure of Native Leukocyte Myeloperoxidase in Complex with the Staphyloccal Peroxidase Inhibitor Spin From Staphylococcus Aureus also contains other interesting chemical elements:

Iron (Fe) 2 atoms
Calcium (Ca) 2 atoms

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Structure of Native Leukocyte Myeloperoxidase in Complex with the Staphyloccal Peroxidase Inhibitor Spin From Staphylococcus Aureus (pdb code 7qzr). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Structure of Native Leukocyte Myeloperoxidase in Complex with the Staphyloccal Peroxidase Inhibitor Spin From Staphylococcus Aureus, PDB code: 7qzr:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in 7qzr

Go back to Chlorine Binding Sites List in 7qzr
Chlorine binding site 1 out of 2 in the Structure of Native Leukocyte Myeloperoxidase in Complex with the Staphyloccal Peroxidase Inhibitor Spin From Staphylococcus Aureus


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Structure of Native Leukocyte Myeloperoxidase in Complex with the Staphyloccal Peroxidase Inhibitor Spin From Staphylococcus Aureus within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl303

b:21.5
occ:1.00
H A:TRP198 2.2 21.6 0.0
H B:VAL493 2.5 18.2 0.0
HA A:ARG197 2.6 22.7 0.0
HH2 B:TRP602 2.7 18.3 0.0
HB3 B:ASN492 2.9 19.5 0.0
HB B:VAL493 3.1 17.9 0.0
N A:TRP198 3.1 23.5 1.0
H A:LEU199 3.2 20.6 0.0
O A:HOH404 3.3 23.3 1.0
H B:ASN492 3.3 18.9 0.0
HB1 B:ALA491 3.4 19.7 0.0
N B:VAL493 3.4 21.4 1.0
HG12 B:VAL493 3.4 18.1 0.0
HG2 A:ARG197 3.5 26.5 0.0
CA A:ARG197 3.5 24.6 1.0
HZ2 B:TRP602 3.5 18.3 0.0
HB2 A:TRP198 3.6 20.4 0.0
CH2 B:TRP602 3.6 21.1 1.0
N B:ASN492 3.8 22.0 1.0
CB B:ASN492 3.8 22.7 1.0
HH11 A:ARG197 3.8 27.9 0.0
C A:ARG197 3.8 24.3 1.0
HD22 B:LEU596 3.8 20.0 0.0
CB B:VAL493 3.9 21.1 1.0
HB3 A:ARG197 4.0 24.3 0.0
HD21 B:LEU596 4.0 19.9 0.0
CG1 B:VAL493 4.0 21.2 1.0
CZ2 B:TRP602 4.0 21.2 1.0
HB2 B:ASN492 4.0 19.6 0.0
HG11 B:VAL493 4.1 18.2 0.0
CA B:ASN492 4.1 21.9 1.0
O A:VAL196 4.1 23.5 1.0
CB A:ARG197 4.1 25.9 1.0
CA A:TRP198 4.1 22.7 1.0
N A:LEU199 4.2 22.2 1.0
C B:ASN492 4.2 21.9 1.0
HD23 B:LEU596 4.2 20.1 0.0
CD2 B:LEU596 4.2 23.1 1.0
HD3 A:ARG197 4.2 29.3 0.0
CA B:VAL493 4.2 21.3 1.0
CG A:ARG197 4.3 28.4 1.0
CB A:TRP198 4.3 22.3 1.0
CB B:ALA491 4.4 22.7 1.0
C B:ALA491 4.5 22.9 1.0
O A:LEU199 4.5 23.4 1.0
HA B:ALA491 4.6 19.8 0.0
HA B:VAL493 4.7 17.9 0.0
C A:TRP198 4.7 22.3 1.0
NH1 A:ARG197 4.7 29.8 1.0
N A:ARG197 4.7 24.3 1.0
HB2 A:LEU199 4.7 21.0 0.0
CD A:ARG197 4.8 31.0 1.0
CZ3 B:TRP602 4.8 21.1 1.0
CA B:ALA491 4.8 22.8 1.0
HB3 B:ALA491 4.8 19.6 0.0
C A:VAL196 4.9 23.6 1.0
CG A:TRP198 4.9 22.3 1.0
HZ3 B:TRP602 5.0 18.5 0.0

Chlorine binding site 2 out of 2 in 7qzr

Go back to Chlorine Binding Sites List in 7qzr
Chlorine binding site 2 out of 2 in the Structure of Native Leukocyte Myeloperoxidase in Complex with the Staphyloccal Peroxidase Inhibitor Spin From Staphylococcus Aureus


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Structure of Native Leukocyte Myeloperoxidase in Complex with the Staphyloccal Peroxidase Inhibitor Spin From Staphylococcus Aureus within 5.0Å range:
probe atom residue distance (Å) B Occ
C:Cl302

b:20.9
occ:1.00
H C:TRP198 2.1 17.1 0.0
H D:VAL493 2.5 18.4 0.0
HA C:ARG197 2.6 18.7 0.0
HH2 D:TRP602 2.8 17.5 0.0
HB3 D:ASN492 2.9 18.1 0.0
O C:HOH420 3.1 25.7 1.0
N C:TRP198 3.1 20.8 1.0
H C:LEU199 3.1 15.6 0.0
H D:ASN492 3.2 17.0 0.0
HG2 C:ARG197 3.3 21.8 0.0
HB D:VAL493 3.3 19.4 0.0
HZ2 D:TRP602 3.4 17.5 0.0
HG12 D:VAL493 3.4 19.6 0.0
N D:VAL493 3.4 22.2 1.0
HB2 C:TRP198 3.5 17.0 0.0
CA C:ARG197 3.5 22.2 1.0
HB1 D:ALA491 3.6 16.7 0.0
CH2 D:TRP602 3.7 20.9 1.0
CB D:ASN492 3.7 21.8 1.0
HB2 D:ASN492 3.8 18.2 0.0
N D:ASN492 3.8 20.7 1.0
HD22 D:LEU596 3.8 22.4 0.0
HH11 C:ARG197 3.8 21.7 0.0
C C:ARG197 3.8 21.6 1.0
HB3 C:ARG197 3.9 20.2 0.0
CZ2 D:TRP602 3.9 20.9 1.0
CB D:VAL493 4.0 23.1 1.0
CB C:ARG197 4.1 23.4 1.0
N C:LEU199 4.1 19.1 1.0
CG1 D:VAL493 4.1 23.4 1.0
CA D:ASN492 4.1 21.2 1.0
CA C:TRP198 4.1 20.6 1.0
HD21 D:LEU596 4.1 22.3 0.0
CG C:ARG197 4.1 25.3 1.0
HG11 D:VAL493 4.2 19.7 0.0
HD23 D:LEU596 4.2 22.5 0.0
CD2 D:LEU596 4.2 26.0 1.0
C D:ASN492 4.2 21.9 1.0
O C:VAL196 4.3 23.7 1.0
CB C:TRP198 4.3 20.7 1.0
CA D:VAL493 4.3 22.4 1.0
O C:LEU199 4.4 19.3 1.0
HB2 C:LEU199 4.5 14.9 0.0
HD3 C:ARG197 4.6 24.6 0.0
C C:TRP198 4.6 19.9 1.0
CB D:ALA491 4.6 20.4 1.0
NH1 C:ARG197 4.6 25.3 1.0
C D:ALA491 4.6 20.5 1.0
N C:ARG197 4.7 22.5 1.0
HA D:VAL493 4.8 18.5 0.0
HA D:ALA491 4.8 16.6 0.0
CZ3 D:TRP602 4.8 20.9 1.0
CG C:TRP198 4.9 21.6 1.0
HG3 C:ARG197 4.9 22.1 0.0
HH12 C:ARG197 4.9 21.6 0.0
CD C:ARG197 4.9 27.8 1.0
C C:VAL196 4.9 23.2 1.0
CA D:ALA491 5.0 20.3 1.0
CG D:ASN492 5.0 24.5 1.0

Reference:

U.Leitgeb, P.G.Furtmuller, S.Hofbauer, J.A.Brito, C.Obinger, V.Pfanzagl. The Staphylococcal Inhibitory Protein Spin Binds to Human Myeloperoxidase with Picomolar Affinity But Only Dampens Halide Oxidation. J.Biol.Chem. V. 298 02514 2022.
ISSN: ESSN 1083-351X
PubMed: 36150500
DOI: 10.1016/J.JBC.2022.102514
Page generated: Sun Jul 13 06:29:24 2025

Last articles

Fe in 2YXO
Fe in 2YRS
Fe in 2YXC
Fe in 2YNM
Fe in 2YVJ
Fe in 2YP1
Fe in 2YU2
Fe in 2YU1
Fe in 2YQB
Fe in 2YOO
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy