Atomistry » Chlorine » PDB 8pm6-8pz0 » 8pz0
Atomistry »
  Chlorine »
    PDB 8pm6-8pz0 »
      8pz0 »

Chlorine in PDB 8pz0: Intracellular Leucine Aminopeptidase of Pseudomonas Aeruginosa PA14.

Enzymatic activity of Intracellular Leucine Aminopeptidase of Pseudomonas Aeruginosa PA14.

All present enzymatic activity of Intracellular Leucine Aminopeptidase of Pseudomonas Aeruginosa PA14.:
3.4.11.1; 3.4.11.10;

Protein crystallography data

The structure of Intracellular Leucine Aminopeptidase of Pseudomonas Aeruginosa PA14., PDB code: 8pz0 was solved by M.C.Simpson, C.M.Czekster, C.J.Harding, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 45.49 / 1.80
Space group P 63 2 2
Cell size a, b, c (Å), α, β, γ (°) 181.95, 181.95, 87.43, 90, 90, 120
R / Rfree (%) 16.8 / 19

Other elements in 8pz0:

The structure of Intracellular Leucine Aminopeptidase of Pseudomonas Aeruginosa PA14. also contains other interesting chemical elements:

Sodium (Na) 5 atoms

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Intracellular Leucine Aminopeptidase of Pseudomonas Aeruginosa PA14. (pdb code 8pz0). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 5 binding sites of Chlorine where determined in the Intracellular Leucine Aminopeptidase of Pseudomonas Aeruginosa PA14., PDB code: 8pz0:
Jump to Chlorine binding site number: 1; 2; 3; 4; 5;

Chlorine binding site 1 out of 5 in 8pz0

Go back to Chlorine Binding Sites List in 8pz0
Chlorine binding site 1 out of 5 in the Intracellular Leucine Aminopeptidase of Pseudomonas Aeruginosa PA14.


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Intracellular Leucine Aminopeptidase of Pseudomonas Aeruginosa PA14. within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl611

b:66.1
occ:1.00
NE2 A:GLN509 3.3 42.7 1.0
CG A:GLU513 3.4 48.4 1.0
O A:HOH777 3.4 39.7 1.0
CA A:ALA426 3.5 36.2 1.0
N A:ALA426 3.7 36.6 1.0
CG A:GLN509 3.8 37.8 1.0
C A:LYS425 3.8 38.7 1.0
O A:LYS425 3.8 36.7 1.0
CG A:LYS425 3.9 45.7 1.0
CD A:GLN509 4.1 41.8 1.0
CB A:ALA426 4.1 36.8 1.0
CE A:LYS425 4.1 63.8 1.0
CD A:GLU513 4.2 52.6 1.0
CD A:LYS425 4.3 45.8 1.0
CB A:PHE429 4.4 36.9 1.0
CB A:LYS425 4.4 37.8 1.0
O A:HOH901 4.4 48.0 1.0
CB A:GLU513 4.5 42.7 1.0
OE1 A:GLU513 4.7 56.8 1.0
CA A:LYS425 4.7 36.9 1.0
C A:ALA426 4.8 36.8 1.0
O A:GLN509 4.8 37.6 1.0
OE2 A:GLU513 4.8 61.6 1.0
CG A:PHE429 4.9 39.8 1.0
O A:GLN422 4.9 35.8 1.0

Chlorine binding site 2 out of 5 in 8pz0

Go back to Chlorine Binding Sites List in 8pz0
Chlorine binding site 2 out of 5 in the Intracellular Leucine Aminopeptidase of Pseudomonas Aeruginosa PA14.


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Intracellular Leucine Aminopeptidase of Pseudomonas Aeruginosa PA14. within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl612

b:69.8
occ:1.00
O A:THR220 3.2 41.5 1.0
NE A:ARG266 3.4 49.0 1.0
CA A:GLY223 3.5 36.8 1.0
CG1 A:VAL240 3.7 47.1 1.0
CA A:THR220 3.8 39.6 1.0
C A:GLY223 3.9 42.2 1.0
C A:THR220 3.9 43.0 1.0
N A:GLU224 3.9 41.2 0.5
N A:GLU224 3.9 41.2 0.5
CD A:ARG266 3.9 46.2 1.0
OE2 A:GLU224 3.9 51.3 0.5
CG2 A:THR220 3.9 47.9 1.0
N A:GLY223 4.2 38.0 1.0
CG A:ARG266 4.3 42.4 1.0
CZ A:ARG266 4.4 52.1 1.0
CB A:THR220 4.4 42.7 1.0
CG A:GLU224 4.4 44.6 0.5
NH2 A:ARG266 4.5 58.8 1.0
NZ A:LYS227 4.6 69.3 1.0
O A:GLY223 4.6 40.7 1.0
CB A:VAL240 4.7 47.0 1.0
CG A:GLU224 4.7 47.4 0.5
O A:PRO219 4.7 38.0 1.0
CD A:GLU224 4.7 48.9 0.5
OG1 A:THR220 4.8 43.0 1.0
CG2 A:VAL240 4.8 45.5 1.0
CA A:GLU224 4.9 42.3 0.5
CA A:GLU224 4.9 42.3 0.5
N A:THR220 5.0 40.3 1.0

Chlorine binding site 3 out of 5 in 8pz0

Go back to Chlorine Binding Sites List in 8pz0
Chlorine binding site 3 out of 5 in the Intracellular Leucine Aminopeptidase of Pseudomonas Aeruginosa PA14.


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Intracellular Leucine Aminopeptidase of Pseudomonas Aeruginosa PA14. within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl613

b:85.9
occ:1.00
O A:HOH1004 2.4 55.8 1.0
NH2 A:ARG266 2.9 58.8 1.0
NH1 A:ARG266 3.0 51.9 1.0
CZ A:ARG266 3.4 52.1 1.0
CB A:PRO264 3.7 52.1 1.0
CG A:PRO264 3.7 52.8 1.0
CB A:ASP242 4.0 46.4 1.0
O A:HOH748 4.1 67.6 1.0
O A:HOH816 4.4 62.9 1.0
OD2 A:ASP242 4.6 59.2 1.0
NE A:ARG266 4.7 49.0 1.0
CG A:ASP242 4.8 54.4 1.0

Chlorine binding site 4 out of 5 in 8pz0

Go back to Chlorine Binding Sites List in 8pz0
Chlorine binding site 4 out of 5 in the Intracellular Leucine Aminopeptidase of Pseudomonas Aeruginosa PA14.


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of Intracellular Leucine Aminopeptidase of Pseudomonas Aeruginosa PA14. within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl614

b:69.2
occ:1.00
N A:SER407 3.1 38.3 1.0
OD1 A:ASN408 3.4 66.9 1.0
CA A:GLY406 3.4 34.7 1.0
OG A:SER407 3.6 52.5 1.0
C A:GLY406 3.8 40.4 1.0
CA A:SER407 4.2 42.8 1.0
CG A:ASN408 4.2 58.0 1.0
N A:ASN408 4.3 41.4 1.0
CB A:SER407 4.3 46.3 1.0
O A:LEU405 4.7 37.3 1.0
C A:SER407 4.7 47.5 1.0
N A:GLY406 4.7 36.6 1.0
ND2 A:ASN408 4.8 59.9 1.0

Chlorine binding site 5 out of 5 in 8pz0

Go back to Chlorine Binding Sites List in 8pz0
Chlorine binding site 5 out of 5 in the Intracellular Leucine Aminopeptidase of Pseudomonas Aeruginosa PA14.


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 5 of Intracellular Leucine Aminopeptidase of Pseudomonas Aeruginosa PA14. within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl615

b:82.6
occ:1.00
OD1 A:ASP185 3.0 56.9 1.0
O A:HOH931 3.6 49.8 1.0
O A:HOH921 3.6 45.3 1.0
O A:ALA184 3.7 49.4 1.0
CA A:ASP185 3.9 46.9 1.0
CG A:ASP185 4.0 56.4 1.0
CB A:ALA188 4.0 42.2 1.0
CB A:ALA143 4.1 43.4 1.0
O A:HOH925 4.3 41.4 1.0
CB A:ASP185 4.3 45.5 1.0
C A:ALA184 4.5 51.6 1.0
N A:ASP185 4.6 45.9 1.0
O A:ASP185 4.8 43.8 1.0
C A:ASP185 4.8 47.0 1.0

Reference:

M.C.Simpson, C.J.Harding, R.M.Czekster, L.Remmel, B.E.Bode, C.M.Czekster. Unveiling the Catalytic Mechanism of A Processive Metalloaminopeptidase. Biochemistry 2023.
ISSN: ISSN 0006-2960
PubMed: 37924287
DOI: 10.1021/ACS.BIOCHEM.3C00420
Page generated: Sun Jul 13 13:19:33 2025

Last articles

Fe in 2YXO
Fe in 2YRS
Fe in 2YXC
Fe in 2YNM
Fe in 2YVJ
Fe in 2YP1
Fe in 2YU2
Fe in 2YU1
Fe in 2YQB
Fe in 2YOO
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy