Chlorine in PDB 9nfm: Tuna P-Glycoprotein Bound to Ddt

The binding sites of Chlorine atom in the Tuna P-Glycoprotein Bound to Ddt (pdb code 9nfm). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 5 binding sites of Chlorine where determined in the Tuna P-Glycoprotein Bound to Ddt, PDB code: 9nfm:
Jump to Chlorine binding site number: 1; 2; 3; 4; 5;

Chlorine binding site 1 out of 5 in the Tuna P-Glycoprotein Bound to Ddt


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Tuna P-Glycoprotein Bound to Ddt within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1401 b:105.4 occ:1.00 CL1 A:6WT1401 0.0 105.4 1.0 C03 A:6WT1401 1.8 105.4 1.0 C04 A:6WT1401 2.7 105.4 1.0 C02 A:6WT1401 2.9 105.4 1.0 CE1 A:PHE315 3.3 76.6 1.0 OE1 A:GLN743 3.7 71.0 1.0 CZ A:PHE315 3.9 76.6 1.0 OE1 A:GLU1007 3.9 97.8 1.0 C01 A:6WT1401 4.1 105.4 1.0 CD A:GLN743 4.1 71.0 1.0 C05 A:6WT1401 4.1 105.4 1.0 CD1 A:PHE315 4.2 76.6 1.0 C06 A:6WT1401 4.6 105.4 1.0 NE2 A:GLN743 4.7 71.0 1.0 CG A:GLN743 4.7 71.0 1.0 CD A:GLU1007 4.8 97.8 1.0 OE2 A:GLU1007 4.9 97.8 1.0

Chlorine binding site 2 out of 5 in the Tuna P-Glycoprotein Bound to Ddt


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Tuna P-Glycoprotein Bound to Ddt within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1401 b:105.4 occ:1.00 CL5 A:6WT1401 0.0 105.4 1.0 C08 A:6WT1401 1.8 105.4 1.0 C07 A:6WT1401 2.7 105.4 1.0 CL3 A:6WT1401 2.9 105.4 1.0 CL4 A:6WT1401 2.9 105.4 1.0 CE2 A:PHE355 3.4 79.6 1.0 C06 A:6WT1401 3.7 105.4 1.0 C09 A:6WT1401 3.8 105.4 1.0 C05 A:6WT1401 4.0 105.4 1.0 CD2 A:PHE355 4.0 79.6 1.0 CZ A:PHE355 4.2 79.6 1.0 C14 A:6WT1401 4.2 105.4 1.0 C01 A:6WT1401 4.9 105.4 1.0 C10 A:6WT1401 4.9 105.4 1.0

Chlorine binding site 3 out of 5 in the Tuna P-Glycoprotein Bound to Ddt


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Tuna P-Glycoprotein Bound to Ddt within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1401 b:105.4 occ:1.00 CL3 A:6WT1401 0.0 105.4 1.0 C08 A:6WT1401 1.8 105.4 1.0 C07 A:6WT1401 2.7 105.4 1.0 C09 A:6WT1401 2.8 105.4 1.0 CL5 A:6WT1401 2.9 105.4 1.0 CL4 A:6WT1401 2.9 105.4 1.0 C10 A:6WT1401 3.1 105.4 1.0 SD A:MET1003 3.4 74.8 1.0 CG A:MET1003 3.4 74.8 1.0 C14 A:6WT1401 3.5 105.4 1.0 C11 A:6WT1401 3.9 105.4 1.0 C06 A:6WT1401 3.9 105.4 1.0 CB A:MET1003 4.0 74.8 1.0 C13 A:6WT1401 4.3 105.4 1.0 CE2 A:PHE355 4.5 79.6 1.0 C01 A:6WT1401 4.5 105.4 1.0 C12 A:6WT1401 4.5 105.4 1.0 CE A:MET1003 4.7 74.8 1.0 CD2 A:PHE355 4.9 79.6 1.0 C05 A:6WT1401 5.0 105.4 1.0

Chlorine binding site 4 out of 5 in the Tuna P-Glycoprotein Bound to Ddt


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of Tuna P-Glycoprotein Bound to Ddt within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1401 b:105.4 occ:1.00 CL4 A:6WT1401 0.0 105.4 1.0 C08 A:6WT1401 1.8 105.4 1.0 C07 A:6WT1401 2.7 105.4 1.0 C06 A:6WT1401 2.8 105.4 1.0 CL5 A:6WT1401 2.9 105.4 1.0 CL3 A:6WT1401 2.9 105.4 1.0 C01 A:6WT1401 3.1 105.4 1.0 C05 A:6WT1401 3.5 105.4 1.0 OE1 A:GLU1007 3.6 97.8 1.0 O A:MET1003 3.7 74.8 1.0 CB A:MET1003 3.8 74.8 1.0 C09 A:6WT1401 3.9 105.4 1.0 C02 A:6WT1401 4.0 105.4 1.0 C A:MET1003 4.0 74.8 1.0 CG A:MET1003 4.2 74.8 1.0 C10 A:6WT1401 4.2 105.4 1.0 CB A:GLU1007 4.3 97.8 1.0 CD A:GLU1007 4.3 97.8 1.0 C04 A:6WT1401 4.4 105.4 1.0 CA A:MET1003 4.4 74.8 1.0 C03 A:6WT1401 4.6 105.4 1.0 N A:ALA1004 4.7 76.0 1.0 CG A:GLU1007 4.7 97.8 1.0 C14 A:6WT1401 5.0 105.4 1.0

Chlorine binding site 5 out of 5 in the Tuna P-Glycoprotein Bound to Ddt


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 5 of Tuna P-Glycoprotein Bound to Ddt within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1401 b:105.4 occ:1.00 CL2 A:6WT1401 0.0 105.4 1.0 C12 A:6WT1401 1.8 105.4 1.0 C13 A:6WT1401 2.7 105.4 1.0 C11 A:6WT1401 2.9 105.4 1.0 CZ A:PHE1000 3.8 70.2 1.0 CE1 A:PHE348 3.8 66.6 1.0 OH A:TYR322 4.0 70.8 1.0 C10 A:6WT1401 4.1 105.4 1.0 C14 A:6WT1401 4.1 105.4 1.0 CE1 A:PHE1000 4.4 70.2 1.0 CE2 A:TYR322 4.5 70.8 1.0 CE2 A:PHE1000 4.5 70.2 1.0 CZ A:PHE348 4.5 66.6 1.0 C09 A:6WT1401 4.6 105.4 1.0 CD1 A:PHE348 4.7 66.6 1.0 CZ A:TYR322 4.7 70.8 1.0

M.A.Young, S.D.Rees, S.C.T.Nicklisch, M.H.B.Stowell, A.Hamdoun, G.Chang. Cryo-Em Structures of Apo and Ddt-Bound P-Glycoprotein in Yellowfin Tuna. Environ Sci Technol. 2025.
ISSN: ESSN 1520-5851
PubMed: 40439033
DOI: 10.1021/ACS.EST.5C03398