Chlorine in PDB 9nov: Human Sweet Taste Receptor (TAS1R2 + TAS1R3) Vft Domains Bound to Sucralose
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Human Sweet Taste Receptor (TAS1R2 + TAS1R3) Vft Domains Bound to Sucralose
(pdb code 9nov). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total 3 binding sites of Chlorine where determined in the
Human Sweet Taste Receptor (TAS1R2 + TAS1R3) Vft Domains Bound to Sucralose, PDB code: 9nov:
Jump to Chlorine binding site number:
1;
2;
3;
Chlorine binding site 1 out
of 3 in 9nov
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Chlorine Binding Sites List in 9nov
Chlorine binding site 1 out
of 3 in the Human Sweet Taste Receptor (TAS1R2 + TAS1R3) Vft Domains Bound to Sucralose
 Mono view
 Stereo pair view
|
A full contact list of Chlorine with other atoms in the Cl binding
site number 1 of Human Sweet Taste Receptor (TAS1R2 + TAS1R3) Vft Domains Bound to Sucralose within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:Cl1
b:117.5
occ:1.00
|
CL6
|
C:RRY1
|
0.0
|
117.5
|
1.0
|
C6
|
C:RRY1
|
1.8
|
106.2
|
1.0
|
C5
|
C:RRY1
|
2.7
|
106.5
|
1.0
|
C4
|
C:RRY1
|
3.0
|
110.1
|
1.0
|
O4
|
C:RRY1
|
3.1
|
110.5
|
1.0
|
NZ
|
A:LYS65
|
3.5
|
97.4
|
1.0
|
CB
|
A:TYR103
|
3.5
|
99.8
|
1.0
|
CD
|
A:LYS65
|
3.9
|
93.4
|
1.0
|
O5
|
C:RRY1
|
4.0
|
103.2
|
1.0
|
CG
|
A:TYR103
|
4.1
|
102.0
|
1.0
|
CB
|
A:ALA43
|
4.2
|
105.5
|
1.0
|
CE
|
A:LYS65
|
4.3
|
95.2
|
1.0
|
CB
|
A:SER40
|
4.3
|
89.0
|
1.0
|
CD1
|
A:TYR103
|
4.3
|
101.5
|
1.0
|
OG
|
A:SER40
|
4.4
|
93.2
|
1.0
|
O6
|
C:RRJ2
|
4.4
|
101.0
|
1.0
|
C3
|
C:RRY1
|
4.4
|
107.3
|
1.0
|
CA
|
A:TYR103
|
4.5
|
96.6
|
1.0
|
CD1
|
A:LEU279
|
4.7
|
96.9
|
1.0
|
C2
|
C:RRY1
|
4.9
|
106.3
|
1.0
|
O
|
A:HIS42
|
4.9
|
94.8
|
1.0
|
|
Chlorine binding site 2 out
of 3 in 9nov
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Chlorine Binding Sites List in 9nov
Chlorine binding site 2 out
of 3 in the Human Sweet Taste Receptor (TAS1R2 + TAS1R3) Vft Domains Bound to Sucralose
 Mono view
 Stereo pair view
|
A full contact list of Chlorine with other atoms in the Cl binding
site number 2 of Human Sweet Taste Receptor (TAS1R2 + TAS1R3) Vft Domains Bound to Sucralose within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:Cl1
b:109.4
occ:1.00
|
CL1
|
C:RRY1
|
0.0
|
109.4
|
1.0
|
C1
|
C:RRY1
|
1.8
|
105.1
|
1.0
|
C2
|
C:RRY1
|
2.7
|
106.3
|
1.0
|
C3
|
C:RRY1
|
2.8
|
107.3
|
1.0
|
O5
|
C:RRY1
|
3.2
|
103.2
|
1.0
|
CB
|
A:ASN143
|
3.6
|
90.9
|
1.0
|
C5
|
C:RRY1
|
3.6
|
106.5
|
1.0
|
C4
|
C:RRY1
|
3.6
|
110.1
|
1.0
|
O4
|
C:RRY1
|
3.8
|
110.5
|
1.0
|
O2
|
C:RRY1
|
3.9
|
103.5
|
1.0
|
O3
|
C:RRY1
|
4.0
|
99.5
|
1.0
|
CE1
|
A:TYR103
|
4.2
|
101.2
|
1.0
|
CA
|
A:ASN143
|
4.5
|
87.4
|
1.0
|
CD1
|
A:TYR103
|
4.6
|
101.5
|
1.0
|
CG
|
A:PRO277
|
4.7
|
82.3
|
1.0
|
CG
|
A:ASN143
|
4.7
|
93.3
|
1.0
|
CB
|
A:PRO277
|
4.8
|
81.8
|
1.0
|
CD2
|
A:TYR215
|
4.8
|
86.2
|
1.0
|
C1
|
C:RRJ2
|
4.9
|
102.1
|
1.0
|
CG
|
A:TYR215
|
5.0
|
89.7
|
1.0
|
|
Chlorine binding site 3 out
of 3 in 9nov
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Chlorine Binding Sites List in 9nov
Chlorine binding site 3 out
of 3 in the Human Sweet Taste Receptor (TAS1R2 + TAS1R3) Vft Domains Bound to Sucralose
 Mono view
 Stereo pair view
|
A full contact list of Chlorine with other atoms in the Cl binding
site number 3 of Human Sweet Taste Receptor (TAS1R2 + TAS1R3) Vft Domains Bound to Sucralose within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:Cl2
b:114.9
occ:1.00
|
CL4
|
C:RRJ2
|
0.0
|
114.9
|
1.0
|
C4
|
C:RRJ2
|
1.8
|
102.2
|
1.0
|
C6
|
C:RRJ2
|
2.7
|
101.8
|
1.0
|
C3
|
C:RRJ2
|
2.7
|
97.1
|
1.0
|
C5
|
C:RRJ2
|
2.7
|
103.3
|
1.0
|
O3
|
C:RRJ2
|
2.9
|
91.7
|
1.0
|
OG
|
A:SER165
|
3.0
|
89.1
|
1.0
|
C2
|
C:RRJ2
|
3.1
|
97.7
|
1.0
|
CB
|
A:SER165
|
3.5
|
85.1
|
1.0
|
O5
|
C:RRJ2
|
3.7
|
105.0
|
1.0
|
CD1
|
A:LEU71
|
3.8
|
64.5
|
1.0
|
C1
|
C:RRJ2
|
3.8
|
102.1
|
1.0
|
CG1
|
A:VAL384
|
3.9
|
70.7
|
1.0
|
O6
|
C:RRJ2
|
4.1
|
101.0
|
1.0
|
CB
|
A:ASP142
|
4.3
|
87.7
|
1.0
|
O2
|
C:RRJ2
|
4.3
|
94.1
|
1.0
|
CG2
|
A:VAL384
|
4.4
|
61.5
|
1.0
|
CB
|
A:VAL384
|
4.5
|
65.3
|
1.0
|
CG2
|
A:ILE67
|
4.6
|
77.3
|
1.0
|
CD1
|
A:TYR164
|
4.6
|
72.3
|
1.0
|
CE1
|
A:TYR164
|
4.7
|
71.4
|
1.0
|
O
|
A:ASP142
|
4.9
|
91.7
|
1.0
|
CA
|
A:SER165
|
5.0
|
80.1
|
1.0
|
|
Reference:
Z.Juen,
Z.Lu,
R.Yu,
A.N.Chang,
B.Wang,
A.W.Fitzpatrick,
C.S.Zuker.
The Structure of Human Sweetness Cell(Cambridge,Mass.) 2025.
ISSN: ISSN 0092-8674
DOI: 10.1016/J.CELL.2025.04.021
Page generated: Sun Jul 13 17:17:25 2025
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