Chlorine in PDB 1a7z: Crystal Structure of Actinomycin Z3

The structure of Crystal Structure of Actinomycin Z3, PDB code: 1a7z was solved by M.Schafer, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	32.45 / 0.95
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	14.803, 24.780, 65.059, 90.00, 90.00, 90.00
R / Rfree (%)	8 / 9.7

The binding sites of Chlorine atom in the Crystal Structure of Actinomycin Z3 (pdb code 1a7z). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 3 binding sites of Chlorine where determined in the Crystal Structure of Actinomycin Z3, PDB code: 1a7z:
Jump to Chlorine binding site number: 1; 2; 3;

Chlorine binding site 1 out of 3 in the Crystal Structure of Actinomycin Z3


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Actinomycin Z3 within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1 b:7.4 occ:1.00 CL2 A:CTH1 0.0 7.4 1.0 CG2 A:CTH1 1.8 4.9 1.0 CB A:CTH1 2.7 3.2 1.0 O A:PXZ6 3.3 3.8 1.0 CA A:CTH1 3.4 3.0 1.0 C1 A:BNZ110 3.6 12.2 1.0 C2 A:BNZ110 3.6 10.6 1.0 CD A:H5M9 3.9 4.8 1.0 OG1 A:CTH1 4.0 3.3 1.0 C A:PXZ6 4.0 3.1 1.0 N A:CTH1 4.1 2.8 1.0 O A:MAA5 4.1 4.5 1.0 O A:DVA8 4.1 3.5 1.0 CD1 A:H5M9 4.2 6.9 1.0 C A:MAA5 4.5 3.5 1.0 C A:CTH1 4.7 2.7 1.0 C6 A:BNZ110 4.8 13.5 1.0 N2 A:PXZ6 4.8 3.6 1.0 C3 A:BNZ110 4.8 9.4 1.0 N A:H5M9 4.9 4.3 1.0 CG A:H5M9 4.9 6.2 1.0 C A:DVA8 4.9 3.5 1.0 N A:DVA2 5.0 3.2 1.0

Chlorine binding site 2 out of 3 in the Crystal Structure of Actinomycin Z3


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of Actinomycin Z3 within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl1 b:5.5 occ:0.85 CL2 B:CTH1 0.0 5.5 0.8 CG2 B:CTH1 1.7 4.9 1.0 CL2 B:CTH1 2.1 6.5 0.1 CB B:CTH1 2.7 3.3 1.0 OG1 B:CTH1 3.0 3.5 1.0 C B:PXZ6 3.2 3.0 1.0 N B:CTH1 3.3 3.0 1.0 O B:PXZ6 3.4 3.6 1.0 CA B:CTH1 3.5 2.9 1.0 C5 A:BNZ109 3.5 13.6 1.0 C4 B:BNZ102 3.7 7.5 1.0 C B:MAA5 3.8 3.5 1.0 C1 B:PXZ6 3.8 3.2 1.0 C5 B:BNZ102 3.9 7.6 1.0 N2 B:PXZ6 3.9 4.5 1.0 C4 A:BNZ109 4.0 13.6 1.0 C2 B:PXZ6 4.0 3.6 1.0 C5 B:BNZ112 4.1 9.1 1.0 O B:MAA5 4.2 4.9 1.0 C6 A:BNZ109 4.5 13.6 1.0 CA B:MAA5 4.6 3.8 1.0 C6 B:BNZ112 4.7 10.2 1.0 C4 B:BNZ112 4.7 9.8 1.0 C B:CTH1 4.8 3.1 1.0 C11 B:PXZ6 4.8 3.3 1.0 C3 B:BNZ102 4.8 6.3 1.0

Chlorine binding site 3 out of 3 in the Crystal Structure of Actinomycin Z3


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Crystal Structure of Actinomycin Z3 within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl1 b:6.5 occ:0.15 CL2 B:CTH1 0.0 6.5 0.1 CG2 B:CTH1 1.7 4.9 1.0 CL2 B:CTH1 2.1 5.5 0.8 CB B:CTH1 2.9 3.3 1.0 O B:MAA5 3.0 4.9 1.0 OG1 B:CTH1 3.2 3.5 1.0 C B:MAA5 3.2 3.5 1.0 C5 B:BNZ102 3.7 7.6 1.0 C6 B:BNZ112 3.9 10.2 1.0 C5 B:BNZ112 4.1 9.1 1.0 CA B:CTH1 4.2 2.9 1.0 CA B:MAA5 4.3 3.8 1.0 C4 B:BNZ102 4.3 7.5 1.0 C6 B:BNZ102 4.5 6.7 1.0 O B:PXZ6 4.6 3.6 1.0 N B:CTH1 4.7 3.0 1.0 C1 B:BNZ112 4.8 15.1 1.0 C B:PXZ6 4.9 3.0 1.0 C4 B:BNZ112 4.9 9.8 1.0

M.Schafer, G.M.Sheldrick, I.Bahner, H.Lackner. Crystal Structures of Actinomycin D and Actinomycin Z3. Angew.Chem.Int.Ed.Engl. V. 37 2381 1998.
ISSN: ESSN 1521-3773
PubMed: 29710967
DOI: 10.1002/(SICI)1521-3773(19980918)37:17<2381::AID-ANIE2381>3.0.CO;2-L