Chlorine in PDB 1b6a: Human Methionine Aminopeptidase 2 Complexed with Tnp-470

All present enzymatic activity of Human Methionine Aminopeptidase 2 Complexed with Tnp-470:
3.4.11.18;

The structure of Human Methionine Aminopeptidase 2 Complexed with Tnp-470, PDB code: 1b6a was solved by S.Liu, J.C.Clardy, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	6.00 / 1.60
Space group	C 2 2 21
Cell size a, b, c (Å), α, β, γ (°)	89.558, 99.060, 101.508, 90.00, 90.00, 90.00
R / Rfree (%)	18.7 / 21.6

The structure of Human Methionine Aminopeptidase 2 Complexed with Tnp-470 also contains other interesting chemical elements:

Cobalt

(Co)

2 atoms

The binding sites of Chlorine atom in the Human Methionine Aminopeptidase 2 Complexed with Tnp-470 (pdb code 1b6a). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Human Methionine Aminopeptidase 2 Complexed with Tnp-470, PDB code: 1b6a:

Chlorine binding site 1 out of 1 in the Human Methionine Aminopeptidase 2 Complexed with Tnp-470


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Human Methionine Aminopeptidase 2 Complexed with Tnp-470 within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl480 b:57.0 occ:1.00 CL4 A:TN4480 0.0 57.0 1.0 C44 A:TN4480 1.8 41.1 1.0 C43 A:TN4480 2.7 37.5 1.0 O4B A:TN4480 3.1 39.1 1.0 O A:HOH693 3.5 39.1 1.0 N42 A:TN4480 3.7 22.7 1.0 O A:ASN327 4.2 22.3 1.0 O A:HOH586 4.6 24.5 1.0 ND2 A:ASN327 4.7 19.8 1.0 CD2 A:LEU447 4.8 18.7 1.0 CD1 A:LEU447 4.9 16.2 1.0 C41 A:TN4480 4.9 22.2 1.0

S.Liu, J.Widom, C.W.Kemp, C.M.Crews, J.Clardy. Structure of Human Methionine Aminopeptidase-2 Complexed with Fumagillin. Science V. 282 1324 1998.
ISSN: ISSN 0036-8075
PubMed: 9812898
DOI: 10.1126/SCIENCE.282.5392.1324