Chlorine in PDB 1ckl: N-Terminal Two Domains of Human CD46 (Membrane Cofactor Protein, Mcp)

The structure of N-Terminal Two Domains of Human CD46 (Membrane Cofactor Protein, Mcp), PDB code: 1ckl was solved by J.Casasnovas, M.Larvie, T.Stehle, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	20.00 / 3.10
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	74.823, 111.204, 136.986, 90.00, 90.00, 90.00
R / Rfree (%)	24.4 / 29.8

The structure of N-Terminal Two Domains of Human CD46 (Membrane Cofactor Protein, Mcp) also contains other interesting chemical elements:

Calcium

(Ca)

6 atoms

The binding sites of Chlorine atom in the N-Terminal Two Domains of Human CD46 (Membrane Cofactor Protein, Mcp) (pdb code 1ckl). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 5 binding sites of Chlorine where determined in the N-Terminal Two Domains of Human CD46 (Membrane Cofactor Protein, Mcp), PDB code: 1ckl:
Jump to Chlorine binding site number: 1; 2; 3; 4; 5;

Chlorine binding site 1 out of 5 in the N-Terminal Two Domains of Human CD46 (Membrane Cofactor Protein, Mcp)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of N-Terminal Two Domains of Human CD46 (Membrane Cofactor Protein, Mcp) within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1042 b:65.8 occ:1.00 ND1 A:HIS43 3.3 60.4 1.0 OG1 A:THR42 3.7 56.0 1.0 CE1 A:HIS43 3.7 72.4 1.0 N A:THR42 3.7 65.6 1.0 CG2 A:THR42 4.2 51.6 1.0 CB A:THR42 4.3 49.4 1.0 CA A:ALA41 4.4 59.2 1.0 C A:ALA41 4.5 66.6 1.0 CA A:THR42 4.5 58.0 1.0 O A:LEU40 4.6 60.0 1.0 CG A:HIS43 4.6 67.4 1.0 NH2 A:ARG25 4.7 59.9 1.0 C A:THR42 4.7 58.2 1.0 N A:HIS43 4.9 48.2 1.0

Chlorine binding site 2 out of 5 in the N-Terminal Two Domains of Human CD46 (Membrane Cofactor Protein, Mcp)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of N-Terminal Two Domains of Human CD46 (Membrane Cofactor Protein, Mcp) within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl2042 b:48.0 occ:1.00 OG1 B:THR42 2.8 55.4 1.0 N B:THR42 3.2 43.8 1.0 ND1 B:HIS43 3.7 59.4 1.0 CA B:THR42 3.9 48.0 1.0 CB B:THR42 3.9 40.5 1.0 C B:THR42 4.0 56.0 1.0 CA B:ALA41 4.0 48.2 1.0 C B:ALA41 4.1 49.5 1.0 O B:THR42 4.3 62.6 1.0 O B:LEU40 4.4 54.3 1.0 CE1 B:HIS43 4.4 58.4 1.0 CG B:HIS43 4.5 59.1 1.0 N B:HIS43 4.5 56.5 1.0 OH B:TYR36 4.6 78.4 1.0 NH2 B:ARG25 4.6 55.5 1.0 CB B:HIS43 4.6 57.0 1.0 CB B:ALA41 4.8 57.1 1.0 CG2 B:THR42 4.9 45.6 1.0

Chlorine binding site 3 out of 5 in the N-Terminal Two Domains of Human CD46 (Membrane Cofactor Protein, Mcp)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of N-Terminal Two Domains of Human CD46 (Membrane Cofactor Protein, Mcp) within 5.0Å range: probe atom residue distance (Å) B Occ D:Cl4042 b:0.6 occ:1.00 N D:THR42 2.6 53.4 1.0 CA D:ALA41 2.7 55.3 1.0 C D:ALA41 3.1 55.2 1.0 CB D:ALA41 3.3 56.8 1.0 OG1 D:THR42 3.3 72.9 1.0 O D:LEU40 3.4 64.5 1.0 CA D:THR42 3.7 59.0 1.0 ND1 D:HIS43 3.7 58.6 1.0 N D:ALA41 3.7 61.0 1.0 C D:LEU40 3.9 58.9 1.0 CB D:THR42 4.0 65.4 1.0 C D:THR42 4.0 49.0 1.0 O D:ALA41 4.3 56.1 1.0 N D:HIS43 4.3 46.2 1.0 OH D:TYR36 4.3 48.5 1.0 CE1 D:HIS43 4.4 63.3 1.0 O D:THR42 4.5 45.4 1.0 CG2 D:THR42 4.6 75.5 1.0 CG D:HIS43 4.8 57.2 1.0 O D:PRO39 4.9 75.3 1.0 CE1 D:TYR36 4.9 53.7 1.0 CB D:HIS43 5.0 53.5 1.0 CZ D:TYR36 5.0 53.8 1.0

Chlorine binding site 4 out of 5 in the N-Terminal Two Domains of Human CD46 (Membrane Cofactor Protein, Mcp)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of N-Terminal Two Domains of Human CD46 (Membrane Cofactor Protein, Mcp) within 5.0Å range: probe atom residue distance (Å) B Occ E:Cl5042 b:57.8 occ:1.00 N E:THR42 3.2 54.9 1.0 OG1 E:THR42 3.4 56.4 1.0 ND1 E:HIS43 3.8 48.7 1.0 CA E:ALA41 3.9 54.8 1.0 CA E:THR42 4.0 51.5 1.0 C E:ALA41 4.0 57.0 1.0 C E:THR42 4.1 54.4 1.0 CB E:ALA41 4.3 50.9 1.0 O E:THR42 4.3 65.7 1.0 CB E:THR42 4.3 54.8 1.0 CE1 E:HIS43 4.5 52.2 1.0 OH E:TYR36 4.6 74.8 1.0 N E:HIS43 4.6 48.0 1.0 CG E:HIS43 4.6 44.9 1.0 NH2 E:ARG25 4.8 59.8 1.0 CB E:HIS43 4.9 40.2 1.0 O E:LEU40 4.9 55.5 1.0

Chlorine binding site 5 out of 5 in the N-Terminal Two Domains of Human CD46 (Membrane Cofactor Protein, Mcp)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 5 of N-Terminal Two Domains of Human CD46 (Membrane Cofactor Protein, Mcp) within 5.0Å range: probe atom residue distance (Å) B Occ F:Cl6042 b:31.4 occ:1.00 ND1 F:HIS43 3.3 43.3 1.0 CB F:ALA41 3.6 54.2 1.0 N F:THR42 3.6 49.5 1.0 CA F:ALA41 3.9 53.5 1.0 OG1 F:THR42 4.0 43.2 1.0 CE1 F:HIS43 4.1 48.8 1.0 O F:THR42 4.3 44.0 1.0 NH2 F:ARG25 4.3 50.9 1.0 C F:THR42 4.3 42.1 1.0 C F:ALA41 4.4 52.9 1.0 CG F:HIS43 4.4 40.3 1.0 CA F:THR42 4.5 43.1 1.0 CB F:HIS43 4.6 37.0 1.0 N F:HIS43 4.7 41.4 1.0 O F:LEU40 4.9 48.6 1.0 CB F:THR42 4.9 46.8 1.0

J.M.Casasnovas, M.Larvie, T.Stehle. Crystal Structure of Two CD46 Domains Reveals An Extended Measles Virus-Binding Surface. Embo J. V. 18 2911 1999.
ISSN: ISSN 0261-4189
PubMed: 10357804
DOI: 10.1093/EMBOJ/18.11.2911