Chlorine in PDB 1dp4: Dimerized Hormone Binding Domain of the Atrial Natriuretic Peptide Receptor

All present enzymatic activity of Dimerized Hormone Binding Domain of the Atrial Natriuretic Peptide Receptor:
4.6.1.2;

The structure of Dimerized Hormone Binding Domain of the Atrial Natriuretic Peptide Receptor, PDB code: 1dp4 was solved by F.Van Den Akker, X.Zhang, M.Miyagi, X.Huo, K.S.Misono, V.C.Yee, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	30.00 / 2.00
Space group	P 41 21 2
Cell size a, b, c (Å), α, β, γ (°)	120.250, 120.250, 160.550, 90.00, 90.00, 90.00
R / Rfree (%)	19.8 / 22.5

The binding sites of Chlorine atom in the Dimerized Hormone Binding Domain of the Atrial Natriuretic Peptide Receptor (pdb code 1dp4). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Dimerized Hormone Binding Domain of the Atrial Natriuretic Peptide Receptor, PDB code: 1dp4:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Dimerized Hormone Binding Domain of the Atrial Natriuretic Peptide Receptor


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Dimerized Hormone Binding Domain of the Atrial Natriuretic Peptide Receptor within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl610 b:18.8 occ:1.00 OG A:SER53 3.1 17.8 1.0 N A:GLY85 3.2 16.7 1.0 N A:CYS86 3.3 17.2 1.0 NE1 A:TRP18 3.6 16.7 1.0 CB A:SER53 3.6 17.6 1.0 CD A:PRO10 3.6 13.9 1.0 CD1 A:TRP18 3.7 14.0 1.0 CB A:PRO84 3.7 13.0 1.0 CG A:PRO10 3.8 15.0 1.0 CB A:CYS86 3.9 21.3 1.0 CA A:GLY85 4.0 14.3 1.0 CA A:PRO84 4.0 14.3 1.0 C A:PRO84 4.1 15.2 1.0 CB A:CYS60 4.1 26.4 1.0 C A:GLY85 4.1 15.8 1.0 SG A:CYS86 4.1 24.8 1.0 CA A:CYS86 4.2 18.2 1.0 CA A:LEU9 4.2 16.4 1.0 CD2 A:LEU9 4.2 14.6 1.0 CB A:SER89 4.3 18.8 1.0 OG A:SER89 4.3 20.3 1.0 N A:PRO10 4.3 16.3 1.0 O A:VAL8 4.5 14.8 1.0 C A:LEU9 4.6 16.3 1.0 CE2 A:TRP18 4.7 14.5 1.0 CG A:TRP18 4.9 14.4 1.0

Chlorine binding site 2 out of 2 in the Dimerized Hormone Binding Domain of the Atrial Natriuretic Peptide Receptor


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Dimerized Hormone Binding Domain of the Atrial Natriuretic Peptide Receptor within 5.0Å range: probe atom residue distance (Å) B Occ C:Cl611 b:21.8 occ:1.00 OG C:SER53 3.0 20.1 1.0 N C:GLY85 3.2 19.0 1.0 N C:CYS86 3.3 21.6 1.0 NE1 C:TRP18 3.6 24.4 1.0 CB C:SER53 3.6 19.6 1.0 CD C:PRO10 3.6 17.9 1.0 CD1 C:TRP18 3.7 19.7 1.0 CB C:PRO84 3.7 18.2 1.0 CG C:PRO10 3.8 17.1 1.0 CB C:CYS86 3.9 23.1 1.0 CA C:GLY85 4.0 18.3 1.0 CA C:PRO84 4.0 16.7 1.0 C C:PRO84 4.1 16.6 1.0 C C:GLY85 4.1 22.4 1.0 CB C:CYS60 4.2 28.6 1.0 SG C:CYS86 4.2 28.2 1.0 CA C:CYS86 4.2 23.9 1.0 CA C:LEU9 4.3 19.4 1.0 CB C:SER89 4.3 20.7 1.0 CD2 C:LEU9 4.3 16.8 1.0 OG C:SER89 4.3 25.1 1.0 N C:PRO10 4.3 19.3 1.0 O C:VAL8 4.5 18.8 1.0 C C:LEU9 4.6 20.2 1.0 CE2 C:TRP18 4.8 22.6 1.0 CG C:TRP18 4.9 23.2 1.0 CG C:PRO84 5.0 16.9 1.0

F.Van Den Akker, X.Zhang, M.Miyagi, X.Huo, K.S.Misono, V.C.Yee. Structure of the Dimerized Hormone-Binding Domain of A Guanylyl-Cyclase-Coupled Receptor. Nature V. 406 101 2000.
ISSN: ISSN 0028-0836
PubMed: 10894551
DOI: 10.1038/35017602