Chlorine in PDB 1dqt: The Crystal Structure of Murine CTLA4 (CD152)

The structure of The Crystal Structure of Murine CTLA4 (CD152), PDB code: 1dqt was solved by D.A.Ostrov, W.Shi, J.C.Schwartz, S.C.Almo, S.G.Nathenson, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	10.00 / 2.00
Space group	P 43 21 2
Cell size a, b, c (Å), α, β, γ (°)	112.850, 112.850, 102.504, 90.00, 90.00, 90.00
R / Rfree (%)	21.1 / 25.4

The binding sites of Chlorine atom in the The Crystal Structure of Murine CTLA4 (CD152) (pdb code 1dqt). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 4 binding sites of Chlorine where determined in the The Crystal Structure of Murine CTLA4 (CD152), PDB code: 1dqt:
Jump to Chlorine binding site number: 1; 2; 3; 4;

Chlorine binding site 1 out of 4 in the The Crystal Structure of Murine CTLA4 (CD152)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of The Crystal Structure of Murine CTLA4 (CD152) within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl201 b:46.4 occ:1.00 O A:HOH929 2.5 25.4 1.0 N A:SER18 3.1 21.1 1.0 O A:VAL16 3.6 20.2 1.0 O B:SER18 3.6 23.7 1.0 CA A:ALA17 3.6 20.7 1.0 O A:SER18 3.7 22.6 1.0 C A:ALA17 3.8 21.2 1.0 CG1 A:VAL9 4.0 22.0 1.0 CA A:SER18 4.0 21.4 1.0 O A:LEU10 4.0 20.4 1.0 O A:HOH513 4.1 21.0 1.0 CB A:SER18 4.2 20.1 1.0 C A:VAL16 4.3 21.7 1.0 N A:ALA17 4.3 21.5 1.0 C A:SER18 4.4 21.9 1.0 CA B:PHE19 4.4 21.3 1.0 CD B:PRO20 4.4 19.9 1.0 C B:SER18 4.6 22.3 1.0 OG A:SER18 4.6 21.2 1.0 CB A:ALA17 4.7 19.6 1.0 CB B:PHE19 4.8 21.1 1.0 N A:SER12 4.9 22.8 1.0 CA A:ALA11 4.9 21.5 1.0 C A:LEU10 4.9 20.1 1.0 N B:PHE19 5.0 21.8 1.0

Chlorine binding site 2 out of 4 in the The Crystal Structure of Murine CTLA4 (CD152)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of The Crystal Structure of Murine CTLA4 (CD152) within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl202 b:50.1 occ:1.00 O B:HOH930 2.5 26.6 1.0 O D:HOH566 3.0 29.9 1.0 O A:ALA11 3.1 21.9 1.0 OE1 D:GLN111 3.4 32.5 1.0 O B:HOH587 3.5 30.2 1.0 CA A:SER12 3.9 23.4 1.0 C A:ALA11 4.0 22.1 1.0 O A:HOH552 4.1 21.3 1.0 OH D:TYR113 4.1 22.7 1.0 N A:SER13 4.3 25.2 1.0 C A:SER12 4.3 24.8 1.0 O D:HOH525 4.3 27.2 1.0 N A:SER12 4.4 22.8 1.0 CB B:PRO6 4.4 20.1 1.0 CD D:GLN111 4.4 30.4 1.0 O A:LEU10 4.4 20.4 1.0 NE2 D:GLN111 4.6 32.6 1.0 C A:LEU10 4.8 20.1 1.0 O A:HOH513 4.8 21.0 1.0 CB A:LEU10 4.8 18.6 1.0 N B:SER7 4.8 22.3 1.0 O B:VAL8 4.8 23.6 1.0 CA B:PRO6 4.9 20.9 1.0

Chlorine binding site 3 out of 4 in the The Crystal Structure of Murine CTLA4 (CD152)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of The Crystal Structure of Murine CTLA4 (CD152) within 5.0Å range: probe atom residue distance (Å) B Occ C:Cl203 b:54.2 occ:1.00 O C:HOH931 2.5 28.7 1.0 N C:SER18 2.9 19.7 1.0 O D:HOH927 3.0 38.5 1.0 CA C:ALA17 3.5 20.2 1.0 O C:SER18 3.6 21.9 1.0 O C:VAL16 3.7 21.0 1.0 C C:ALA17 3.7 20.9 1.0 O D:SER18 3.7 25.1 1.0 CG1 C:VAL9 3.7 20.3 1.0 CA C:SER18 3.9 20.9 1.0 O C:LEU10 4.1 20.5 1.0 CB C:SER18 4.1 19.9 1.0 C C:SER18 4.2 21.8 1.0 N C:ALA17 4.3 21.4 1.0 C C:VAL16 4.3 21.2 1.0 O C:HOH537 4.3 23.7 1.0 CB C:ALA17 4.6 20.5 1.0 OG C:SER18 4.6 21.2 1.0 CA D:PHE19 4.7 24.0 1.0 CD D:PRO20 4.7 21.2 1.0 C D:SER18 4.7 24.8 1.0 CA C:ALA11 4.9 22.5 1.0 C C:LEU10 4.9 20.6 1.0 O C:ALA17 4.9 19.0 1.0 N C:SER12 5.0 23.6 1.0

Chlorine binding site 4 out of 4 in the The Crystal Structure of Murine CTLA4 (CD152)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of The Crystal Structure of Murine CTLA4 (CD152) within 5.0Å range: probe atom residue distance (Å) B Occ D:Cl204 b:47.7 occ:1.00 O C:HOH932 2.5 27.8 1.0 N D:VAL8 3.1 20.8 1.0 O D:VAL8 3.3 23.4 1.0 O D:HOH521 3.5 27.4 1.0 N D:SER7 3.6 22.5 1.0 CB D:SER7 3.8 22.2 1.0 CA D:VAL8 3.8 21.9 1.0 CG2 B:VAL8 3.9 20.3 1.0 CB D:VAL8 3.9 21.7 1.0 CA D:SER7 4.0 22.9 1.0 NE2 B:GLN111 4.0 29.7 1.0 C D:SER7 4.0 21.9 1.0 C D:VAL8 4.0 21.7 1.0 CB D:PRO6 4.3 22.1 1.0 C D:PRO6 4.4 23.2 1.0 O C:HOH537 4.5 23.7 1.0 CA D:PRO6 4.6 22.3 1.0 CG2 D:VAL8 4.7 21.4 1.0 OG D:SER7 4.8 27.2 1.0 OH B:TYR113 4.9 22.4 1.0 CB C:LEU10 4.9 20.1 1.0 CD1 C:LEU10 5.0 19.3 1.0

D.A.Ostrov, W.Shi, J.C.Schwartz, S.C.Almo, S.G.Nathenson. Structure of Murine Ctla-4 and Its Role in Modulating T Cell Responsiveness. Science V. 290 816 2000.
ISSN: ISSN 0036-8075
PubMed: 11052947
DOI: 10.1126/SCIENCE.290.5492.816