Chlorine in PDB 1e1y: Flavopiridol Inhibits Glycogen Phosphorylase By Binding at the Inhibitor Site

All present enzymatic activity of Flavopiridol Inhibits Glycogen Phosphorylase By Binding at the Inhibitor Site:
2.4.1.1;

The structure of Flavopiridol Inhibits Glycogen Phosphorylase By Binding at the Inhibitor Site, PDB code: 1e1y was solved by N.G.Oikonomakos, S.E.Zographos, V.T.Skamnaki, K.E.Tsitsanou, L.N.Johnson, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	29.90 / 2.23
Space group	P 43 21 2
Cell size a, b, c (Å), α, β, γ (°)	126.759, 126.759, 116.018, 90.00, 90.00, 90.00
R / Rfree (%)	19.5 / 25.2

The binding sites of Chlorine atom in the Flavopiridol Inhibits Glycogen Phosphorylase By Binding at the Inhibitor Site (pdb code 1e1y). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Flavopiridol Inhibits Glycogen Phosphorylase By Binding at the Inhibitor Site, PDB code: 1e1y:

Chlorine binding site 1 out of 1 in the Flavopiridol Inhibits Glycogen Phosphorylase By Binding at the Inhibitor Site


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Flavopiridol Inhibits Glycogen Phosphorylase By Binding at the Inhibitor Site within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl940 b:29.3 occ:1.00 CL1 A:CPB940 0.0 29.3 1.0 C22 A:CPB940 1.7 17.4 1.0 C23 A:CPB940 2.7 21.6 1.0 C21 A:CPB940 2.8 21.7 1.0 O1 A:CPB940 3.1 21.0 1.0 C2 A:CPB940 3.2 18.9 1.0 OH A:TYR613 3.4 15.6 1.0 OE2 A:GLU572 3.6 23.5 1.0 CZ A:TYR613 3.8 11.8 1.0 CE1 A:TYR613 3.9 10.7 1.0 O A:HOH2179 4.0 41.8 1.0 C24 A:CPB940 4.0 17.8 1.0 C26 A:CPB940 4.1 18.3 1.0 C9 A:CPB940 4.2 25.1 1.0 C14 A:CPB940 4.2 37.4 1.0 C15 A:CPB940 4.3 41.6 1.0 C3 A:CPB940 4.4 20.6 1.0 C16 A:CPB940 4.5 44.2 1.0 C25 A:CPB940 4.6 20.6 1.0 CD A:GLU572 4.6 16.5 1.0 NH1 A:ARG770 4.7 44.1 1.0 C8 A:CPB940 4.7 30.2 1.0 CE2 A:TYR613 4.8 12.8 1.0 O A:HOH2432 4.9 11.1 1.0 CD1 A:TYR613 4.9 11.5 1.0

N.G.Oikonomakos, J.B.Schnier, S.E.Zographos, V.T.Skamnaki, K.E.Tsitsanou, L.N.Johnson. Flavopiridol Inhibits Glycogen Phosphorylase By Binding at the Inhibitor Site J.Biol.Chem. V. 275 34566 2000.
ISSN: ISSN 0021-9258
PubMed: 10924512
DOI: 10.1074/JBC.M004485200