Chlorine in PDB 1ean: The RUNX1 Runt Domain at 1.70A Resolution: A Structural Switch and Specifically Bound Chloride Ions Modulate Dna Binding

The structure of The RUNX1 Runt Domain at 1.70A Resolution: A Structural Switch and Specifically Bound Chloride Ions Modulate Dna Binding, PDB code: 1ean was solved by S.Backstrom, M.Wolf-Watz, C.Grundstrom, T.Hard, T.Grundstrom, U.H.Sauer, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	20.00 / 1.70
Space group	H 3 2
Cell size a, b, c (Å), α, β, γ (°)	110.696, 110.696, 117.293, 90.00, 90.00, 120.00
R / Rfree (%)	20.4 / 22.2

The binding sites of Chlorine atom in the The RUNX1 Runt Domain at 1.70A Resolution: A Structural Switch and Specifically Bound Chloride Ions Modulate Dna Binding (pdb code 1ean). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the The RUNX1 Runt Domain at 1.70A Resolution: A Structural Switch and Specifically Bound Chloride Ions Modulate Dna Binding, PDB code: 1ean:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the The RUNX1 Runt Domain at 1.70A Resolution: A Structural Switch and Specifically Bound Chloride Ions Modulate Dna Binding


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of The RUNX1 Runt Domain at 1.70A Resolution: A Structural Switch and Specifically Bound Chloride Ions Modulate Dna Binding within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1174 b:42.4 occ:1.00 N A:VAL170 3.3 20.2 1.0 NE A:ARG139 3.3 20.5 1.0 O A:HOH2074 3.4 57.5 1.0 NH2 A:ARG139 3.6 20.2 1.0 CA A:THR169 3.7 20.1 1.0 CB A:THR169 3.9 20.3 1.0 CZ A:ARG139 3.9 19.7 1.0 CA A:GLY141 3.9 28.4 1.0 C A:THR169 4.0 20.1 1.0 CG1 A:VAL170 4.0 21.2 1.0 CB A:VAL170 4.2 20.6 1.0 CB A:ARG139 4.2 21.5 1.0 CA A:VAL170 4.3 20.7 1.0 CG2 A:THR169 4.4 20.3 1.0 CG A:ARG139 4.4 21.3 1.0 CD A:ARG139 4.4 20.6 1.0 N A:GLY141 4.6 27.2 1.0 O A:HOH2115 4.7 37.1 1.0 O A:ILE168 4.7 20.2 1.0 N A:THR169 5.0 20.2 1.0

Chlorine binding site 2 out of 2 in the The RUNX1 Runt Domain at 1.70A Resolution: A Structural Switch and Specifically Bound Chloride Ions Modulate Dna Binding


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of The RUNX1 Runt Domain at 1.70A Resolution: A Structural Switch and Specifically Bound Chloride Ions Modulate Dna Binding within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1175 b:46.0 occ:1.00 O A:HOH2064 3.0 44.5 1.0 N A:GLU116 3.2 22.6 1.0 CA A:GLY138 3.6 21.1 1.0 ND2 A:ASN112 3.7 32.2 1.0 CA A:ALA115 3.8 24.2 1.0 CB A:GLU116 3.8 22.0 1.0 C A:ALA115 3.9 23.6 1.0 CA A:GLU116 4.1 22.3 1.0 CB A:ALA115 4.2 24.5 1.0 O A:HOH2093 4.4 39.8 1.0 N A:GLY138 4.4 21.5 1.0 CG A:ASN112 4.7 31.4 1.0 OD1 A:ASN112 4.7 32.5 1.0 C A:GLY138 4.8 21.2 1.0 O A:SER114 4.9 26.5 1.0 OE1 A:GLU116 5.0 23.6 1.0

S.Backstrom, M.Wolf-Watz, C.Grundstrom, T.Hard, T.Grundstrom, U.H.Sauer. The RUNX1 Runt Domain at 1.25 A Resolution: A Structural Switch and Specifically Bound Chloride Ions Modulate Dna Binding J.Mol.Biol. V. 322 259 2002.
ISSN: ISSN 0022-2836
PubMed: 12217689
DOI: 10.1016/S0022-2836(02)00702-7