Chlorine in PDB 1ev6: Structure of the Monoclinic Form of the M-Cresol/Insulin R6 Hexamer

The structure of Structure of the Monoclinic Form of the M-Cresol/Insulin R6 Hexamer, PDB code: 1ev6 was solved by G.D.Smith, E.Ciszak, L.A.Magrum, W.A.Pangborn, R.H.Blessing, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	20.95 / 1.90
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	61.247, 61.739, 47.467, 90.00, 111.32, 90.00
R / Rfree (%)	19.5 / 23.5

The structure of Structure of the Monoclinic Form of the M-Cresol/Insulin R6 Hexamer also contains other interesting chemical elements:

Zinc	(Zn)	2 atoms
Sodium	(Na)	1 atom

The binding sites of Chlorine atom in the Structure of the Monoclinic Form of the M-Cresol/Insulin R6 Hexamer (pdb code 1ev6). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Structure of the Monoclinic Form of the M-Cresol/Insulin R6 Hexamer, PDB code: 1ev6:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Structure of the Monoclinic Form of the M-Cresol/Insulin R6 Hexamer


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Structure of the Monoclinic Form of the M-Cresol/Insulin R6 Hexamer within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl303 b:21.9 occ:1.00 ZN B:ZN301 2.2 22.4 1.0 NE2 J:HIS10 3.4 21.1 1.0 NE2 B:HIS10 3.5 23.0 1.0 NE2 F:HIS10 3.5 21.2 1.0 CD1 J:LEU6 3.8 22.9 1.0 CD2 B:HIS10 3.9 19.1 1.0 CB B:LEU6 3.9 20.1 1.0 CB J:LEU6 3.9 20.5 1.0 CD2 J:HIS10 3.9 17.3 1.0 CB F:LEU6 3.9 21.0 1.0 CD2 F:HIS10 3.9 20.7 1.0 CD1 B:LEU6 4.0 23.6 1.0 O F:HOH37 4.1 41.0 1.0 CG J:LEU6 4.2 19.2 1.0 CD1 F:LEU6 4.2 28.1 1.0 CE1 J:HIS10 4.4 21.2 1.0 CD2 J:LEU6 4.4 20.1 1.0 CG B:LEU6 4.4 25.3 1.0 CG F:LEU6 4.5 25.8 1.0 CE1 F:HIS10 4.5 24.3 1.0 CD2 F:LEU6 4.5 26.3 1.0 CE1 B:HIS10 4.5 24.8 1.0 O B:LEU6 4.7 18.7 1.0 CD2 B:LEU6 4.7 26.8 1.0 O F:LEU6 4.8 20.6 1.0 CA F:LEU6 4.8 22.6 1.0 CA B:LEU6 4.8 17.5 1.0 C B:LEU6 4.9 19.9 1.0 CA J:LEU6 4.9 20.2 1.0 C F:LEU6 4.9 21.2 1.0 O J:LEU6 4.9 18.6 1.0

Chlorine binding site 2 out of 2 in the Structure of the Monoclinic Form of the M-Cresol/Insulin R6 Hexamer


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Structure of the Monoclinic Form of the M-Cresol/Insulin R6 Hexamer within 5.0Å range: probe atom residue distance (Å) B Occ D:Cl304 b:21.9 occ:1.00 ZN D:ZN302 2.2 23.2 1.0 NE2 D:HIS10 3.5 23.0 1.0 NE2 L:HIS10 3.5 22.5 1.0 NE2 H:HIS10 3.5 23.0 1.0 CD2 H:HIS10 3.8 19.6 1.0 CB D:LEU6 3.9 25.2 1.0 CD2 D:HIS10 3.9 22.2 1.0 CB L:LEU6 3.9 23.6 1.0 CB H:LEU6 3.9 23.0 1.0 CD2 L:HIS10 3.9 22.0 1.0 CD1 D:LEU6 4.0 26.9 1.0 CD1 L:LEU6 4.2 25.2 1.0 CD1 H:LEU6 4.3 26.8 1.0 CD2 L:LEU6 4.4 26.5 1.0 CG D:LEU6 4.4 24.7 1.0 CG L:LEU6 4.4 24.5 1.0 CE1 D:HIS10 4.5 25.9 1.0 CG H:LEU6 4.6 28.0 1.0 CD2 D:LEU6 4.6 27.9 1.0 CE1 L:HIS10 4.6 24.7 1.0 CE1 H:HIS10 4.6 23.3 1.0 CD2 H:LEU6 4.8 28.1 1.0 O H:LEU6 4.8 25.1 1.0 O L:LEU6 4.8 18.6 1.0 CA D:LEU6 4.8 24.5 1.0 CA L:LEU6 4.9 21.1 1.0 O D:LEU6 4.9 25.2 1.0 CA H:LEU6 4.9 22.2 1.0 C D:LEU6 4.9 25.1 1.0 C L:LEU6 4.9 21.6 1.0 C H:LEU6 4.9 21.7 1.0

G.D.Smith, E.Ciszak, L.A.Magrum, W.A.Pangborn, R.H.Blessing. R6 Hexameric Insulin Complexed with M-Cresol or Resorcinol Biochem.Biophys.Res.Commun. V. 56 1541 2000.
ISSN: ISSN 0006-291X
PubMed: 11092919
DOI: 10.1107/S0907444900012749