Chlorine »
PDB 1eyz-1g0g »
1fcm »
Chlorine in PDB 1fcm: Crystal Structure of the E.Coli Ampc Beta-Lactamase Mutant Q120L/Y150E Covalently Acylated with the Inhibitory Beta-Lactam, Cloxacillin
Enzymatic activity of Crystal Structure of the E.Coli Ampc Beta-Lactamase Mutant Q120L/Y150E Covalently Acylated with the Inhibitory Beta-Lactam, Cloxacillin
All present enzymatic activity of Crystal Structure of the E.Coli Ampc Beta-Lactamase Mutant Q120L/Y150E Covalently Acylated with the Inhibitory Beta-Lactam, Cloxacillin:
3.5.2.6;
3.5.2.6;
Protein crystallography data
The structure of Crystal Structure of the E.Coli Ampc Beta-Lactamase Mutant Q120L/Y150E Covalently Acylated with the Inhibitory Beta-Lactam, Cloxacillin, PDB code: 1fcm
was solved by
A.Patera,
L.C.Blaszczak,
B.K.Shoichet,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 20.00 / 2.46 |
| Space group | C 1 2 1 |
| Cell size a, b, c (Å), α, β, γ (°) | 118.520, 76.190, 98.280, 90.00, 116.68, 90.00 |
| R / Rfree (%) | 20.7 / 26.5 |
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Crystal Structure of the E.Coli Ampc Beta-Lactamase Mutant Q120L/Y150E Covalently Acylated with the Inhibitory Beta-Lactam, Cloxacillin
(pdb code 1fcm). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Crystal Structure of the E.Coli Ampc Beta-Lactamase Mutant Q120L/Y150E Covalently Acylated with the Inhibitory Beta-Lactam, Cloxacillin, PDB code: 1fcm:
Jump to Chlorine binding site number: 1; 2;
In total 2 binding sites of Chlorine where determined in the Crystal Structure of the E.Coli Ampc Beta-Lactamase Mutant Q120L/Y150E Covalently Acylated with the Inhibitory Beta-Lactam, Cloxacillin, PDB code: 1fcm:
Jump to Chlorine binding site number: 1; 2;
Chlorine binding site 1 out of 2 in 1fcm
Go back to
Chlorine Binding Sites List in 1fcm
Chlorine binding site 1 out
of 2 in the Crystal Structure of the E.Coli Ampc Beta-Lactamase Mutant Q120L/Y150E Covalently Acylated with the Inhibitory Beta-Lactam, Cloxacillin
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Chlorine with other atoms in the Cl binding
site number 1 of Crystal Structure of the E.Coli Ampc Beta-Lactamase Mutant Q120L/Y150E Covalently Acylated with the Inhibitory Beta-Lactam, Cloxacillin within 5.0Å range:
|
Chlorine binding site 2 out of 2 in 1fcm
Go back to
Chlorine Binding Sites List in 1fcm
Chlorine binding site 2 out
of 2 in the Crystal Structure of the E.Coli Ampc Beta-Lactamase Mutant Q120L/Y150E Covalently Acylated with the Inhibitory Beta-Lactam, Cloxacillin
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Chlorine with other atoms in the Cl binding
site number 2 of Crystal Structure of the E.Coli Ampc Beta-Lactamase Mutant Q120L/Y150E Covalently Acylated with the Inhibitory Beta-Lactam, Cloxacillin within 5.0Å range:
|
Reference:
A.Patera,
L.C.Blaszczak,
B.K.Shoichet.
Crystal Structures of Substrate and Inhibitor Complexes with Ampc -Lactamase: Possible Implications For Substrate-Assisted Catalysis J.Am.Chem.Soc. V. 122 10504 2000.
ISSN: ISSN 0002-7863
DOI: 10.1021/JA001676X
Page generated: Sat Dec 12 08:35:17 2020
ISSN: ISSN 0002-7863
DOI: 10.1021/JA001676X
Last articles
Zn in 8WB0Zn in 8WAX
Zn in 8WAU
Zn in 8WAZ
Zn in 8WAY
Zn in 8WAV
Zn in 8WAW
Zn in 8WAT
Zn in 8W7M
Zn in 8WD3
