Chlorine in PDB 1gq5: Structural Determinants of the Nherf Interaction with BETA2-Ar and Pdgfr

The structure of Structural Determinants of the Nherf Interaction with BETA2-Ar and Pdgfr, PDB code: 1gq5 was solved by S.Karthikeyan, T.Leung, J.A.A.Ladias, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	26.4 / 2.2
Space group	P 31 2 1
Cell size a, b, c (Å), α, β, γ (°)	50.073, 50.073, 66.680, 90.00, 90.00, 120.00
R / Rfree (%)	22.2 / 26.3

The binding sites of Chlorine atom in the Structural Determinants of the Nherf Interaction with BETA2-Ar and Pdgfr (pdb code 1gq5). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Structural Determinants of the Nherf Interaction with BETA2-Ar and Pdgfr, PDB code: 1gq5:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Structural Determinants of the Nherf Interaction with BETA2-Ar and Pdgfr


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Structural Determinants of the Nherf Interaction with BETA2-Ar and Pdgfr within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1100 b:34.1 occ:1.00 O A:HOH2014 2.9 46.2 1.0 N A:LEU41 3.0 29.3 1.0 CB A:ALA55 3.6 28.3 1.0 CG A:ARG40 3.7 31.9 1.0 CA A:ARG40 3.8 30.1 1.0 C A:ARG40 3.9 29.8 1.0 CA A:LEU41 3.9 28.3 1.0 CB A:ARG40 4.0 30.4 1.0 CG A:LEU41 4.0 29.7 1.0 CD2 A:LEU41 4.4 27.5 1.0 CB A:LEU41 4.6 28.6 1.0 NE A:ARG40 4.7 35.7 1.0 CD A:ARG40 4.8 34.0 1.0 O A:HOH2013 4.9 26.6 1.0 CA A:ALA55 4.9 29.3 1.0 O A:HOH2016 5.0 28.0 1.0

Chlorine binding site 2 out of 2 in the Structural Determinants of the Nherf Interaction with BETA2-Ar and Pdgfr


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Structural Determinants of the Nherf Interaction with BETA2-Ar and Pdgfr within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1101 b:33.6 occ:1.00 N A:ASP92 3.1 25.6 1.0 O A:HOH2003 3.1 36.7 1.0 CA A:VAL91 3.5 25.6 1.0 CB A:VAL91 3.6 24.9 1.0 C A:VAL91 3.8 25.8 1.0 CG1 A:VAL91 4.0 25.9 1.0 CB A:ASP92 4.1 26.9 1.0 CA A:ASP92 4.1 26.9 1.0 O A:ASP92 4.3 27.5 1.0 CB A:ASP96 4.5 27.6 1.0 C A:ASP92 4.6 26.9 1.0 CB A:GLU95 4.8 33.6 1.0 O A:VAL90 4.9 25.6 1.0 N A:VAL91 4.9 24.6 1.0

S.Karthikeyan, T.Leung, J.A.A.Ladias. Structural Determinants of the Na+/H+ Exchanger Regulatory Factor Interaction with the Beta 2 Adrenergic and Platelet-Derived Growth Factor Receptors J.Biol.Chem. V. 277 18973 2002.
ISSN: ISSN 0021-9258
PubMed: 11882663
DOI: 10.1074/JBC.M201507200