Atomistry » Chlorine » PDB 1hba-1i3k » 1i3k
Atomistry »
  Chlorine »
    PDB 1hba-1i3k »
      1i3k »

Chlorine in PDB 1i3k: Molecular Basis For Severe Epimerase-Deficiency Galactosemia: X-Ray Structure of the Human V94M-Substituted Udp-Galactose 4-Epimerase

Enzymatic activity of Molecular Basis For Severe Epimerase-Deficiency Galactosemia: X-Ray Structure of the Human V94M-Substituted Udp-Galactose 4-Epimerase

All present enzymatic activity of Molecular Basis For Severe Epimerase-Deficiency Galactosemia: X-Ray Structure of the Human V94M-Substituted Udp-Galactose 4-Epimerase:
5.1.3.2;

Protein crystallography data

The structure of Molecular Basis For Severe Epimerase-Deficiency Galactosemia: X-Ray Structure of the Human V94M-Substituted Udp-Galactose 4-Epimerase, PDB code: 1i3k was solved by J.B.Thoden, T.M.Wohlers, J.L.Fridovich-Keil, H.M.Holden, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 50.00 / 1.50
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 78.100, 89.900, 96.900, 90.00, 90.00, 90.00
R / Rfree (%) n/a / n/a

Other elements in 1i3k:

The structure of Molecular Basis For Severe Epimerase-Deficiency Galactosemia: X-Ray Structure of the Human V94M-Substituted Udp-Galactose 4-Epimerase also contains other interesting chemical elements:

Magnesium (Mg) 1 atom

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Molecular Basis For Severe Epimerase-Deficiency Galactosemia: X-Ray Structure of the Human V94M-Substituted Udp-Galactose 4-Epimerase (pdb code 1i3k). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 4 binding sites of Chlorine where determined in the Molecular Basis For Severe Epimerase-Deficiency Galactosemia: X-Ray Structure of the Human V94M-Substituted Udp-Galactose 4-Epimerase, PDB code: 1i3k:
Jump to Chlorine binding site number: 1; 2; 3; 4;

Chlorine binding site 1 out of 4 in 1i3k

Go back to Chlorine Binding Sites List in 1i3k
Chlorine binding site 1 out of 4 in the Molecular Basis For Severe Epimerase-Deficiency Galactosemia: X-Ray Structure of the Human V94M-Substituted Udp-Galactose 4-Epimerase


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Molecular Basis For Severe Epimerase-Deficiency Galactosemia: X-Ray Structure of the Human V94M-Substituted Udp-Galactose 4-Epimerase within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl950

b:33.0
occ:1.00
O A:HOH1257 3.1 18.1 1.0
O A:HOH1598 3.3 43.1 1.0
N A:LEU45 3.3 19.6 1.0
N A:SER44 3.6 24.5 1.0
CB A:LEU45 3.6 14.5 1.0
CA A:GLY43 3.7 25.2 1.0
CG A:LEU45 3.8 16.1 1.0
C A:GLY43 3.9 34.8 1.0
CA A:LEU45 4.0 15.8 1.0
CD1 A:LEU45 4.0 21.4 1.0
OG A:SER44 4.2 33.5 1.0
CG A:ARG50 4.2 22.1 1.0
O A:HOH1917 4.2 47.9 1.0
N A:GLY43 4.3 24.6 1.0
C A:SER44 4.4 23.9 1.0
O A:HOH1382 4.4 44.2 1.0
CD A:ARG50 4.4 20.3 1.0
CA A:SER44 4.4 31.9 1.0
O A:LEU45 4.5 16.6 1.0
CB A:ARG50 4.7 14.1 1.0
C A:LEU45 4.7 16.9 1.0
O A:GLY43 4.8 22.0 1.0
CB A:SER44 4.9 27.1 1.0

Chlorine binding site 2 out of 4 in 1i3k

Go back to Chlorine Binding Sites List in 1i3k
Chlorine binding site 2 out of 4 in the Molecular Basis For Severe Epimerase-Deficiency Galactosemia: X-Ray Structure of the Human V94M-Substituted Udp-Galactose 4-Epimerase


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Molecular Basis For Severe Epimerase-Deficiency Galactosemia: X-Ray Structure of the Human V94M-Substituted Udp-Galactose 4-Epimerase within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Cl951

b:30.8
occ:1.00
O B:HOH1517 3.2 28.2 1.0
N B:LEU102 3.3 17.4 1.0
CB B:LEU102 3.4 17.0 1.0
CG B:LEU102 3.7 21.7 1.0
CD B:PRO101 3.7 17.4 1.0
C B:LYS100 3.8 28.0 1.0
CA B:LEU102 3.8 21.1 1.0
N B:PRO101 3.9 24.6 1.0
CA B:LYS100 3.9 43.4 1.0
O B:LYS100 4.2 27.6 1.0
CE A:LYS120 4.2 17.4 1.0
CD1 B:LEU102 4.2 17.9 1.0
CD A:LYS120 4.3 23.3 1.0
C B:PRO101 4.4 18.1 1.0
N B:ASP103 4.5 19.2 1.0
CG B:PRO101 4.5 28.0 1.0
O A:HOH1273 4.5 28.7 1.0
CD1 A:LEU171 4.5 31.9 1.0
CB B:LYS100 4.5 37.0 1.0
CA B:PRO101 4.5 37.6 1.0
C B:LEU102 4.7 20.6 1.0
NZ A:LYS120 4.7 21.8 1.0
O B:GLN99 4.8 46.1 1.0
CB B:PRO101 4.9 25.4 1.0

Chlorine binding site 3 out of 4 in 1i3k

Go back to Chlorine Binding Sites List in 1i3k
Chlorine binding site 3 out of 4 in the Molecular Basis For Severe Epimerase-Deficiency Galactosemia: X-Ray Structure of the Human V94M-Substituted Udp-Galactose 4-Epimerase


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Molecular Basis For Severe Epimerase-Deficiency Galactosemia: X-Ray Structure of the Human V94M-Substituted Udp-Galactose 4-Epimerase within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Cl952

b:37.0
occ:1.00
O B:HOH1721 3.1 22.2 1.0
O B:HOH2003 3.3 54.5 1.0
N B:LEU45 3.7 25.3 1.0
N B:SER44 3.7 39.0 1.0
CA B:GLY43 3.7 30.6 1.0
OG B:SER44 3.8 57.9 1.0
CB B:LEU45 3.9 14.5 1.0
CG B:LEU45 4.0 18.0 1.0
C B:GLY43 4.1 29.1 1.0
CD1 B:LEU45 4.1 19.1 1.0
CG B:ARG50 4.1 22.6 1.0
CD B:ARG50 4.2 21.3 1.0
N B:GLY43 4.2 35.6 1.0
CA B:LEU45 4.4 18.0 1.0
O B:HOH2004 4.5 45.5 1.0
CB B:ARG50 4.6 17.9 1.0
CA B:SER44 4.6 41.9 1.0
C B:SER44 4.7 28.0 1.0
O B:LEU45 4.7 18.1 1.0
CB B:SER44 4.8 33.8 1.0
O B:HOH1724 4.9 34.0 1.0
C B:LEU45 5.0 21.9 1.0

Chlorine binding site 4 out of 4 in 1i3k

Go back to Chlorine Binding Sites List in 1i3k
Chlorine binding site 4 out of 4 in the Molecular Basis For Severe Epimerase-Deficiency Galactosemia: X-Ray Structure of the Human V94M-Substituted Udp-Galactose 4-Epimerase


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of Molecular Basis For Severe Epimerase-Deficiency Galactosemia: X-Ray Structure of the Human V94M-Substituted Udp-Galactose 4-Epimerase within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Cl953

b:33.4
occ:1.00
N B:SER81 3.3 16.6 1.0
CA B:TYR80 3.7 20.0 1.0
OE1 B:GLU3 3.7 80.5 1.0
CE B:LYS4 3.9 34.2 1.0
CD1 B:TYR80 4.0 26.7 1.0
CB B:TYR80 4.1 18.8 1.0
C B:TYR80 4.1 13.9 1.0
CG B:LYS4 4.1 23.9 1.0
CB B:SER81 4.2 18.3 0.5
CD B:LYS4 4.3 43.2 1.0
CA B:SER81 4.3 20.9 1.0
CB B:SER81 4.3 24.2 0.5
O B:SER81 4.4 19.7 1.0
O B:LYS79 4.4 26.9 1.0
CG B:TYR80 4.5 16.9 1.0
OG B:SER81 4.7 91.2 0.5
C B:SER81 4.7 16.9 1.0
NZ B:LYS4 4.8 46.2 1.0
CD B:GLU3 4.8 0.0 1.0
N B:TYR80 4.9 19.9 1.0

Reference:

J.B.Thoden, T.M.Wohlers, J.L.Fridovich-Keil, H.M.Holden. Molecular Basis For Severe Epimerase Deficiency Galactosemia. X-Ray Structure of the Human V94M-Substituted Udp-Galactose 4-Epimerase. J.Biol.Chem. V. 276 20617 2001.
ISSN: ISSN 0021-9258
PubMed: 11279193
DOI: 10.1074/JBC.M101304200
Page generated: Sat Dec 12 08:37:29 2020

Last articles

Zn in 8WB0
Zn in 8WAX
Zn in 8WAU
Zn in 8WAZ
Zn in 8WAY
Zn in 8WAV
Zn in 8WAW
Zn in 8WAT
Zn in 8W7M
Zn in 8WD3
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy