Chlorine in PDB 1i92: Structural Basis of the Nherf PDZ1-Cftr Interaction

The structure of Structural Basis of the Nherf PDZ1-Cftr Interaction, PDB code: 1i92 was solved by S.Karthikeyan, T.Leung, J.A.A.Ladias, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	26.81 / 1.70
Space group	P 31 2 1
Cell size a, b, c (Å), α, β, γ (°)	51.658, 51.658, 66.966, 90.00, 90.00, 120.00
R / Rfree (%)	18.7 / 21.7

The binding sites of Chlorine atom in the Structural Basis of the Nherf PDZ1-Cftr Interaction (pdb code 1i92). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Structural Basis of the Nherf PDZ1-Cftr Interaction, PDB code: 1i92:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Structural Basis of the Nherf PDZ1-Cftr Interaction


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Structural Basis of the Nherf PDZ1-Cftr Interaction within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl101 b:27.0 occ:1.00 N A:ASP92 3.3 19.9 1.0 O A:HOH146 3.3 49.4 1.0 O A:HOH121 3.4 37.3 1.0 CB A:ASP92 3.8 21.2 1.0 CA A:VAL91 3.9 17.7 1.0 CB A:VAL91 3.9 16.7 1.0 C A:VAL91 4.1 18.9 1.0 CA A:ASP92 4.1 20.8 1.0 O A:ASP92 4.3 20.2 1.0 CG1 A:VAL91 4.3 19.0 1.0 CB A:ASP96 4.4 19.8 1.0 C A:ASP92 4.7 21.1 1.0 CB A:GLN95 4.7 25.6 1.0

Chlorine binding site 2 out of 2 in the Structural Basis of the Nherf PDZ1-Cftr Interaction


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Structural Basis of the Nherf PDZ1-Cftr Interaction within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl102 b:30.6 occ:1.00 N A:LEU41 3.4 16.5 1.0 CB A:ARG40 3.4 21.2 1.0 CA A:ARG40 3.8 17.6 1.0 CB A:ALA55 3.9 21.9 1.0 C A:ARG40 4.1 16.5 1.0 CG A:LEU41 4.2 18.8 1.0 CA A:LEU41 4.3 15.2 1.0 CG A:ARG40 4.4 24.2 1.0 CD2 A:LEU41 4.5 20.2 1.0 O A:HOH105 4.6 17.3 1.0 CB A:LEU41 4.8 15.4 1.0 CD A:ARG40 4.9 28.8 1.0 NE A:ARG40 5.0 26.2 1.0

S.Karthikeyan, T.Leung, J.A.Ladias. Structural Basis of the Na+/H+ Exchanger Regulatory Factor PDZ1 Interaction with the Carboxyl-Terminal Region of the Cystic Fibrosis Transmembrane Conductance Regulator. J.Biol.Chem. V. 276 19683 2001.
ISSN: ISSN 0021-9258
PubMed: 11304524
DOI: 10.1074/JBC.C100154200