Chlorine in PDB 1klz: Crystal Structure of Orotidine Monophosphate Decarboxylase Mutant D70A Complexed with Ump

All present enzymatic activity of Crystal Structure of Orotidine Monophosphate Decarboxylase Mutant D70A Complexed with Ump:
4.1.1.23;

The structure of Crystal Structure of Orotidine Monophosphate Decarboxylase Mutant D70A Complexed with Ump, PDB code: 1klz was solved by N.Wu, W.Gillon, E.F.Pai, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	29.64 / 1.50
Space group	C 2 2 21
Cell size a, b, c (Å), α, β, γ (°)	58.225, 103.295, 74.582, 90.00, 90.00, 90.00
R / Rfree (%)	17.4 / 19.7

The binding sites of Chlorine atom in the Crystal Structure of Orotidine Monophosphate Decarboxylase Mutant D70A Complexed with Ump (pdb code 1klz). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Crystal Structure of Orotidine Monophosphate Decarboxylase Mutant D70A Complexed with Ump, PDB code: 1klz:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Crystal Structure of Orotidine Monophosphate Decarboxylase Mutant D70A Complexed with Ump


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Orotidine Monophosphate Decarboxylase Mutant D70A Complexed with Ump within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl5001 b:11.8 occ:1.00 NZ A:LYS72 3.0 11.5 0.5 NZ A:LYS42 3.1 8.1 1.0 NZ A:LYS72 3.1 9.7 0.5 C6 A:U2001 3.4 7.2 1.0 CB A:ALA70 3.4 9.6 1.0 CE A:LYS72 3.5 11.2 0.5 CD1 A:ILE96 3.5 9.7 1.0 CE A:LYS42 3.7 8.1 1.0 CD A:LYS42 3.8 9.0 1.0 C1' A:U2001 3.9 6.4 1.0 CD A:LYS72 3.9 9.0 0.5 CE A:LYS72 4.0 10.9 0.5 CA A:ALA70 4.1 7.3 1.0 CG A:LYS72 4.1 7.2 0.5 N1 A:U2001 4.1 5.8 1.0 O A:ALA70 4.3 12.4 1.0 C5 A:U2001 4.3 6.7 1.0 O4' A:U2001 4.4 6.0 1.0 C A:ALA70 4.5 8.6 1.0 CG2 A:ILE96 4.6 8.6 1.0 CG1 A:ILE96 4.7 9.3 1.0 CG A:LYS42 4.8 7.9 1.0 CB A:ILE96 4.8 7.7 1.0 O A:HOH3006 4.8 17.3 1.0 O2' A:U2001 4.9 8.1 1.0 O3' A:U2001 4.9 6.8 1.0 C2' A:U2001 5.0 6.7 1.0 CD A:LYS72 5.0 11.6 0.5

Chlorine binding site 2 out of 2 in the Crystal Structure of Orotidine Monophosphate Decarboxylase Mutant D70A Complexed with Ump


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of Orotidine Monophosphate Decarboxylase Mutant D70A Complexed with Ump within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl5002 b:14.8 occ:1.00 O A:HOH3004 2.8 14.5 1.0 O A:HOH3001 2.8 19.3 1.0 CG A:LYS72 3.9 10.8 0.5 CD A:LYS72 4.1 11.6 0.5 O A:PHE71 4.4 8.7 1.0 CD1 A:TYR45 4.5 7.2 1.0 CE1 A:TYR45 4.6 7.0 1.0 CE A:LYS72 4.6 10.9 0.5 O A:HOH3003 4.8 22.8 1.0 CB A:LYS72 5.0 9.2 0.5

N.Wu, W.Gillon, E.F.Pai. Mapping the Active Site-Ligand Interactions of Orotidine 5'-Monophosphate Decarboxylase By Crystallography. Biochemistry V. 41 4002 2002.
ISSN: ISSN 0006-2960
PubMed: 11900543
DOI: 10.1021/BI015758P