Chlorine in PDB 1kzn: Crystal Structure of E. Coli 24KDA Domain in Complex with Clorobiocin

All present enzymatic activity of Crystal Structure of E. Coli 24KDA Domain in Complex with Clorobiocin:
5.99.1.3;

The structure of Crystal Structure of E. Coli 24KDA Domain in Complex with Clorobiocin, PDB code: 1kzn was solved by D.Lafitte, V.Lamour, P.O.Tsvetkov, A.A.Makarov, M.Klich, P.Deprez, D.Moras, C.Briand, R.Gilli, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	14.79 / 2.30
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	40.714, 47.629, 111.599, 90.00, 90.00, 90.00
R / Rfree (%)	23.9 / 26.7

The binding sites of Chlorine atom in the Crystal Structure of E. Coli 24KDA Domain in Complex with Clorobiocin (pdb code 1kzn). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of E. Coli 24KDA Domain in Complex with Clorobiocin, PDB code: 1kzn:

Chlorine binding site 1 out of 1 in the Crystal Structure of E. Coli 24KDA Domain in Complex with Clorobiocin


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of E. Coli 24KDA Domain in Complex with Clorobiocin within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1 b:14.4 occ:1.00 CL1 A:CBN1 0.0 14.4 1.0 C28 A:CBN1 1.7 15.5 1.0 C4 A:CBN1 2.7 15.7 1.0 C27 A:CBN1 2.8 14.2 1.0 O4 A:CBN1 3.0 13.1 1.0 O6 A:CBN1 3.0 16.3 1.0 O A:GLY77 3.2 16.3 1.0 OE2 A:GLU50 3.7 17.0 1.0 C A:GLY77 3.7 15.3 1.0 CD A:PRO79 3.8 15.7 1.0 CD A:GLU50 3.9 19.3 1.0 NH1 A:ARG136 3.9 16.6 1.0 CA A:ILE78 4.0 14.3 1.0 N A:ILE78 4.1 14.9 1.0 OE1 A:GLU50 4.1 17.5 1.0 C32 A:CBN1 4.1 15.0 1.0 C8 A:CBN1 4.1 10.6 1.0 C35 A:CBN1 4.2 14.2 1.0 NE A:ARG76 4.2 17.4 1.0 N A:GLY77 4.3 16.4 1.0 NH1 A:ARG76 4.3 16.6 1.0 CB A:ARG76 4.4 17.1 1.0 C23 A:CBN1 4.4 11.5 1.0 C11 A:CBN1 4.4 15.6 1.0 CZ A:ARG76 4.5 17.9 1.0 CG A:GLU50 4.6 19.0 1.0 N A:PRO79 4.6 16.9 1.0 CG A:PRO79 4.6 15.9 1.0 CA A:GLY77 4.7 15.2 1.0 C33 A:CBN1 4.7 14.5 1.0 O10 A:CBN1 4.7 12.6 1.0 C21 A:CBN1 4.7 12.5 1.0 C A:ILE78 4.7 15.8 1.0 C22 A:CBN1 4.9 12.5 1.0 C A:ARG76 4.9 15.8 1.0 O A:HOH1001 4.9 5.9 1.0 O3 A:CBN1 4.9 10.5 1.0

D.Lafitte, V.Lamour, P.O.Tsvetkov, A.A.Makarov, M.Klich, P.Deprez, D.Moras, C.Briand, R.Gilli. Dna Gyrase Interaction with Coumarin-Based Inhibitors: the Role of the Hydroxybenzoate Isopentenyl Moiety and the 5'-Methyl Group of the Noviose. Biochemistry V. 41 7217 2002.
ISSN: ISSN 0006-2960
PubMed: 12044152
DOI: 10.1021/BI0159837