Chlorine in PDB 1l9y: Fez-1-Y228A, A Mutant of the Metallo-Beta-Lactamase From Legionella Gormanii

All present enzymatic activity of Fez-1-Y228A, A Mutant of the Metallo-Beta-Lactamase From Legionella Gormanii:
3.5.2.6;

The structure of Fez-1-Y228A, A Mutant of the Metallo-Beta-Lactamase From Legionella Gormanii, PDB code: 1l9y was solved by I.Garcia-Saez, P.S.Mercuri, M.Galleni, O.Dideberg, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	25.00 / 2.01
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	44.761, 77.430, 78.499, 90.00, 101.70, 90.00
R / Rfree (%)	18.6 / 21.6

The structure of Fez-1-Y228A, A Mutant of the Metallo-Beta-Lactamase From Legionella Gormanii also contains other interesting chemical elements:

Zinc

(Zn)

4 atoms

The binding sites of Chlorine atom in the Fez-1-Y228A, A Mutant of the Metallo-Beta-Lactamase From Legionella Gormanii (pdb code 1l9y). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Fez-1-Y228A, A Mutant of the Metallo-Beta-Lactamase From Legionella Gormanii, PDB code: 1l9y:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Fez-1-Y228A, A Mutant of the Metallo-Beta-Lactamase From Legionella Gormanii


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Fez-1-Y228A, A Mutant of the Metallo-Beta-Lactamase From Legionella Gormanii within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl400 b:36.7 occ:1.00 OH A:TYR293 3.5 9.9 1.0 O A:HOH720 3.7 19.9 1.0 CE1 A:TYR293 3.9 9.2 1.0 NZ A:LYS297 3.9 12.3 1.0 CE A:LYS297 4.1 11.7 1.0 CD A:LYS297 4.1 11.0 1.0 CZ A:TYR293 4.2 9.7 1.0 O A:HOH735 4.3 30.6 1.0 O A:HOH724 4.5 34.5 1.0 CG A:MET266 4.7 14.1 1.0

Chlorine binding site 2 out of 2 in the Fez-1-Y228A, A Mutant of the Metallo-Beta-Lactamase From Legionella Gormanii


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Fez-1-Y228A, A Mutant of the Metallo-Beta-Lactamase From Legionella Gormanii within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl401 b:42.1 occ:1.00 O B:HOH740 3.1 17.2 1.0 OH B:TYR293 3.2 9.4 1.0 CE1 B:TYR293 3.9 9.4 1.0 CZ B:TYR293 4.0 8.8 1.0 NZ B:LYS297 4.1 14.3 1.0 CD B:LYS297 4.1 12.0 1.0 CE B:LYS297 4.2 12.2 1.0 CG B:MET266 4.3 12.1 1.0 O B:HOH766 4.5 38.5 1.0 O B:HOH613 4.8 9.3 1.0 CE B:MET266 4.8 14.2 1.0

I.Garcia-Saez, P.S.Mercuri, C.Papamicael, R.Kahn, J.M.Frre, M.Galleni, G.M.Rossolini, O.Dideberg. Three-Dimensional Structure of Fez-1, A Monomeric Subclass B3 Metallo-Beta-Lactamase From Fluoribacter Gormanii, in Native Form and in Complex with -Captopril J.Mol.Biol. V. 325 651 2003.
ISSN: ISSN 0022-2836
PubMed: 12507470
DOI: 10.1016/S0022-2836(02)01271-8