Chlorine in PDB 1nw7: Structure of the Beta Class N6-Adenine Dna Methyltransferase Rsri Bound to S-Adenosyl-L-Homocysteine

All present enzymatic activity of Structure of the Beta Class N6-Adenine Dna Methyltransferase Rsri Bound to S-Adenosyl-L-Homocysteine:
2.1.1.72;

The structure of Structure of the Beta Class N6-Adenine Dna Methyltransferase Rsri Bound to S-Adenosyl-L-Homocysteine, PDB code: 1nw7 was solved by C.B.Thomas, R.D.Scavetta, R.I.Gumport, M.E.A.Churchill, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	32.56 / 2.10
Space group	C 2 2 21
Cell size a, b, c (Å), α, β, γ (°)	71.169, 130.752, 67.516, 90.00, 90.00, 90.00
R / Rfree (%)	20.9 / 24.7

The binding sites of Chlorine atom in the Structure of the Beta Class N6-Adenine Dna Methyltransferase Rsri Bound to S-Adenosyl-L-Homocysteine (pdb code 1nw7). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Structure of the Beta Class N6-Adenine Dna Methyltransferase Rsri Bound to S-Adenosyl-L-Homocysteine, PDB code: 1nw7:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Structure of the Beta Class N6-Adenine Dna Methyltransferase Rsri Bound to S-Adenosyl-L-Homocysteine


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Structure of the Beta Class N6-Adenine Dna Methyltransferase Rsri Bound to S-Adenosyl-L-Homocysteine within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl501 b:21.8 occ:1.00 NZ A:LYS227 2.9 27.6 1.0 OG A:SER253 3.1 26.6 1.0 O A:HOH614 3.3 29.2 1.0 N A:LYS227 3.3 23.4 1.0 N A:SER253 3.6 23.5 1.0 CA A:GLN226 3.7 24.5 1.0 CE A:LYS227 3.8 29.1 1.0 CB A:SER253 3.8 22.9 1.0 CG1 A:VAL255 4.0 16.0 1.0 C A:GLN226 4.0 23.9 1.0 O A:ALA251 4.1 19.7 1.0 CG A:LYS227 4.1 25.5 1.0 O A:THR225 4.1 23.0 1.0 CB A:LYS227 4.2 23.8 1.0 O A:HOH577 4.3 34.1 1.0 O A:HOH541 4.3 21.6 1.0 CA A:SER253 4.3 24.2 1.0 CA A:LYS227 4.4 25.1 1.0 CG A:GLN226 4.5 26.4 1.0 N A:GLN226 4.5 24.2 1.0 CA A:GLY252 4.5 22.4 1.0 CB A:GLN226 4.6 25.6 1.0 C A:GLY252 4.6 23.5 1.0 CD A:LYS227 4.6 28.1 1.0 C A:THR225 4.6 24.7 1.0 CB A:VAL255 4.8 17.5 1.0 OD2 A:ASP65 4.9 16.1 1.0 C A:ALA251 4.9 18.0 1.0 O A:LYS227 5.0 26.8 1.0 N A:GLY254 5.0 22.4 1.0 ND1 A:HIS223 5.0 31.9 1.0

Chlorine binding site 2 out of 2 in the Structure of the Beta Class N6-Adenine Dna Methyltransferase Rsri Bound to S-Adenosyl-L-Homocysteine


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Structure of the Beta Class N6-Adenine Dna Methyltransferase Rsri Bound to S-Adenosyl-L-Homocysteine within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl502 b:25.9 occ:1.00 ND2 A:ASN136 3.0 15.2 1.0 ND2 A:ASN206 3.1 12.4 1.0 N A:LEU137 3.2 16.9 1.0 CA A:ASN136 3.7 17.7 1.0 O A:LEU137 4.0 14.0 1.0 C A:ASN136 4.0 18.5 1.0 CG A:ASN136 4.1 19.3 1.0 CA A:LEU137 4.2 15.7 1.0 CB A:ASN136 4.3 19.3 1.0 CG A:ASN206 4.4 16.5 1.0 CB A:LEU137 4.4 15.5 1.0 C A:LEU137 4.4 15.9 1.0 CB A:ASN206 4.8 17.5 1.0 N A:ASN136 4.8 18.6 1.0 O A:ALA135 4.8 17.4 1.0 O A:HOH632 5.0 38.2 1.0

C.B.Thomas, R.D.Scavetta, R.I.Gumport, M.E.A.Churchill. Structures of Liganded and Unliganded Rsri N6-Adenine Dna Methyltransferase: A Distinct Orientation For Active Cofactor Binding J.Biol.Chem. V. 278 26094 2003.
ISSN: ISSN 0021-9258
PubMed: 12732637
DOI: 10.1074/JBC.M303751200