Chlorine in PDB 1os3: Dehydrated T6 Human Insulin at 100 K

The structure of Dehydrated T6 Human Insulin at 100 K, PDB code: 1os3 was solved by G.D.Smith, R.H.Blessing, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	16.42 / 1.95
Space group	H 3
Cell size a, b, c (Å), α, β, γ (°)	81.510, 81.510, 33.760, 90.00, 90.00, 120.00
R / Rfree (%)	21.6 / 25.3

The structure of Dehydrated T6 Human Insulin at 100 K also contains other interesting chemical elements:

Zinc

(Zn)

2 atoms

The binding sites of Chlorine atom in the Dehydrated T6 Human Insulin at 100 K (pdb code 1os3). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Dehydrated T6 Human Insulin at 100 K, PDB code: 1os3:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Dehydrated T6 Human Insulin at 100 K


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Dehydrated T6 Human Insulin at 100 K within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl503 b:44.7 occ:0.17 O B:HOH505 2.1 18.2 0.5 ZN B:ZN501 2.4 22.7 0.3 O B:HOH616 3.7 42.8 1.0 NE2 B:HIS10 3.8 19.4 1.0 CD2 B:HIS10 4.2 22.8 1.0 CE1 B:HIS10 5.0 24.0 1.0

Chlorine binding site 2 out of 2 in the Dehydrated T6 Human Insulin at 100 K


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Dehydrated T6 Human Insulin at 100 K within 5.0Å range: probe atom residue distance (Å) B Occ D:Cl504 b:35.2 occ:0.17 O D:HOH506 1.9 20.2 0.5 ZN D:ZN502 2.4 23.0 0.3 NE2 D:HIS10 3.7 17.5 1.0 CD2 D:HIS10 4.2 18.3 1.0 O D:HOH635 4.4 57.5 1.0 CE1 D:HIS10 4.9 20.1 1.0

G.D.Smith, R.H.Blessing. Lessons From An Aged, Dried Crystal of T(6) Human Insulin. Acta Crystallogr.,Sect.D V. 59 1384 2003.
ISSN: ISSN 0907-4449
PubMed: 12876340
DOI: 10.1107/S090744490301165X