Chlorine in PDB 1qj0: Human Insulin Hexamers with Chain B His Mutated to Tyr

The structure of Human Insulin Hexamers with Chain B His Mutated to Tyr, PDB code: 1qj0 was solved by L.Tang, J.L.Whittingham, C.S.Verma, L.S.D.Caves, G.G.Dodson, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	25.70 / 2.40
Space group	H 3
Cell size a, b, c (Å), α, β, γ (°)	80.940, 80.940, 37.630, 90.00, 90.00, 120.00
R / Rfree (%)	19.9 / n/a

The structure of Human Insulin Hexamers with Chain B His Mutated to Tyr also contains other interesting chemical elements:

Zinc

(Zn)

2 atoms

The binding sites of Chlorine atom in the Human Insulin Hexamers with Chain B His Mutated to Tyr (pdb code 1qj0). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Human Insulin Hexamers with Chain B His Mutated to Tyr, PDB code: 1qj0:

Chlorine binding site 1 out of 1 in the Human Insulin Hexamers with Chain B His Mutated to Tyr


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Human Insulin Hexamers with Chain B His Mutated to Tyr within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl1002 b:15.3 occ:0.33 ZN B:ZN1001 2.1 11.0 0.3 NE2 B:HIS10 3.3 13.2 1.0 CB B:LEU6 3.9 16.6 1.0 CD2 B:HIS10 4.0 15.4 1.0 CD1 B:LEU6 4.2 20.1 1.0 CE1 B:HIS10 4.3 13.7 1.0 CG B:LEU6 4.5 19.8 1.0 CD2 B:LEU6 4.6 17.3 1.0 O B:LEU6 4.6 16.9 1.0 C B:LEU6 4.8 18.5 1.0 CA B:LEU6 4.8 16.7 1.0

L.Tang, J.L.Whittingham, C.S.Verma, L.S.D.Caves, G.G.Dodson. Structural Consequences of the B5 Histidine --> Tyrosine Mutation in Human Insulin Characterized By X-Ray Crystallography and Conformational Analysis. Biochemistry V. 38 12041 1999.
ISSN: ISSN 0006-2960
PubMed: 10508408
DOI: 10.1021/BI990700K