Chlorine in PDB 1qol: Structure of the Fmdv Leader Protease

The structure of Structure of the Fmdv Leader Protease, PDB code: 1qol was solved by A.Guarne, J.Tormo, R.Kirchweger, D.Pfistermueller, T.Skern, I.Fita, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	19.99 / 3.00
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	65.430, 101.560, 276.970, 90.00, 90.00, 90.00
R / Rfree (%)	25.8 / 31.4

The binding sites of Chlorine atom in the Structure of the Fmdv Leader Protease (pdb code 1qol). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 3 binding sites of Chlorine where determined in the Structure of the Fmdv Leader Protease, PDB code: 1qol:
Jump to Chlorine binding site number: 1; 2; 3;

Chlorine binding site 1 out of 3 in the Structure of the Fmdv Leader Protease


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Structure of the Fmdv Leader Protease within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl302 b:35.4 occ:1.00 N C:ALA135 3.3 12.8 1.0 CB B:ALA135 3.3 12.3 1.0 N B:ALA135 3.5 21.9 1.0 CB C:ALA135 3.5 5.3 1.0 N C:LEU134 3.8 21.8 1.0 CA C:ALA135 4.0 9.7 1.0 CA B:ALA135 4.0 18.6 1.0 N B:LEU134 4.0 25.6 1.0 CB B:CYS133 4.0 25.3 1.0 CB C:CYS133 4.1 23.6 1.0 C C:LEU134 4.2 16.0 1.0 CB C:LEU134 4.2 24.7 1.0 CA C:LEU134 4.3 19.2 1.0 C B:LEU134 4.3 23.6 1.0 C C:CYS133 4.4 22.4 1.0 CB B:LEU134 4.4 23.7 1.0 CA B:LEU134 4.5 25.1 1.0 C B:CYS133 4.6 25.4 1.0 CA C:CYS133 4.7 21.8 1.0 SG B:CYS133 4.7 25.2 1.0 CA B:CYS133 4.8 25.2 1.0

Chlorine binding site 2 out of 3 in the Structure of the Fmdv Leader Protease


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Structure of the Fmdv Leader Protease within 5.0Å range: probe atom residue distance (Å) B Occ D:Cl301 b:22.7 occ:1.00 N D:ALA135 3.2 14.4 1.0 CB D:ALA135 3.5 12.6 1.0 N D:LEU134 3.6 23.4 1.0 N A:ALA135 3.7 16.9 1.0 CB A:ALA135 3.7 11.0 1.0 CB D:CYS133 3.8 30.8 1.0 N A:LEU134 3.9 24.5 1.0 CA D:ALA135 4.0 13.9 1.0 CB A:CYS133 4.1 21.8 1.0 C D:LEU134 4.1 15.3 1.0 CB A:LEU134 4.2 25.3 1.0 CB D:LEU134 4.2 19.0 1.0 CA D:LEU134 4.2 19.1 1.0 C D:CYS133 4.3 27.5 1.0 CA A:ALA135 4.3 14.4 1.0 CA A:LEU134 4.3 26.6 1.0 C A:LEU134 4.4 24.1 1.0 CA D:CYS133 4.4 28.9 1.0 C A:CYS133 4.5 25.9 1.0 SG D:CYS133 4.7 27.0 1.0 CA A:CYS133 4.8 25.3 1.0 SG A:CYS133 4.8 23.9 1.0

Chlorine binding site 3 out of 3 in the Structure of the Fmdv Leader Protease


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Structure of the Fmdv Leader Protease within 5.0Å range: probe atom residue distance (Å) B Occ E:Cl301 b:75.4 occ:1.00 CB G:CYS133 3.1 50.6 1.0 CB E:CYS133 3.2 38.8 1.0 N G:LEU134 3.5 44.3 1.0 N E:ALA135 3.5 43.4 1.0 CB E:ALA135 3.5 42.9 1.0 CA G:CYS133 3.7 48.6 1.0 N G:ALA135 3.7 44.3 1.0 N E:LEU134 3.8 41.4 1.0 SG G:CYS133 3.8 51.6 1.0 C G:CYS133 3.9 45.6 1.0 C E:CYS133 3.9 42.4 1.0 CB G:ALA135 4.0 45.4 1.0 CA E:CYS133 4.0 41.2 1.0 SG E:CYS133 4.1 34.9 1.0 CA E:ALA135 4.1 42.5 1.0 C E:LEU134 4.3 43.6 1.0 CA G:LEU134 4.4 43.1 1.0 CB G:LEU134 4.4 41.7 1.0 CA E:LEU134 4.4 42.6 1.0 CA G:ALA135 4.5 43.8 1.0 CB E:LEU134 4.5 44.3 1.0 C G:LEU134 4.6 43.8 1.0 O E:CYS133 4.6 43.0 1.0 O G:CYS133 4.9 42.3 1.0

A.Guarne, J.Tormo, R.Kirchweger, D.Pfistermueller, I.Fita, T.Skern. Structure of the Foot-and-Mouth Disease Virus Leader Protease: A Papain-Like Fold Adapted For Self-Processing and EIF4G Recognition. Embo J. V. 17 7469 1998.
ISSN: ISSN 0261-4189
PubMed: 9857201
DOI: 10.1093/EMBOJ/17.24.7469