Chlorine in PDB 1rt4: Hiv-1 Reverse Transcriptase Complexed with UC781

All present enzymatic activity of Hiv-1 Reverse Transcriptase Complexed with UC781:
2.7.7.49;

The structure of Hiv-1 Reverse Transcriptase Complexed with UC781, PDB code: 1rt4 was solved by J.Ren, D.K.Stammers, D.I.Stuart, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	30.00 / 2.90
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	140.400, 111.200, 73.400, 90.00, 90.00, 90.00
R / Rfree (%)	23.7 / 29.5

The binding sites of Chlorine atom in the Hiv-1 Reverse Transcriptase Complexed with UC781 (pdb code 1rt4). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Hiv-1 Reverse Transcriptase Complexed with UC781, PDB code: 1rt4:

Chlorine binding site 1 out of 1 in the Hiv-1 Reverse Transcriptase Complexed with UC781


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Hiv-1 Reverse Transcriptase Complexed with UC781 within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl999 b:34.8 occ:1.00 CL A:UC1999 0.0 34.8 1.0 C4 A:UC1999 1.7 17.0 1.0 C5 A:UC1999 2.7 19.6 1.0 C3 A:UC1999 2.7 18.3 1.0 OB A:UC1999 3.0 28.7 1.0 CB A:LEU234 3.5 25.7 1.0 CD2 A:PHE227 3.6 50.2 1.0 C A:LEU234 3.6 43.5 1.0 O A:LEU234 3.7 41.4 1.0 C A:HIS235 3.8 47.6 1.0 N A:HIS235 3.9 38.2 1.0 N A:PRO236 3.9 51.9 1.0 C6 A:UC1999 3.9 19.4 1.0 O A:HIS235 4.0 38.5 1.0 C2 A:UC1999 4.0 23.9 1.0 OH A:TYR318 4.0 11.1 1.0 CA A:HIS235 4.1 44.6 1.0 CA A:LEU234 4.2 39.2 1.0 CG2 A:VAL106 4.3 15.2 1.0 CE2 A:PHE227 4.3 57.4 1.0 CG A:LEU234 4.3 29.6 1.0 CA A:PRO236 4.4 47.7 1.0 CC A:UC1999 4.4 37.1 1.0 CD A:PRO236 4.4 50.6 1.0 C1 A:UC1999 4.5 27.2 1.0 CD2 A:LEU234 4.5 27.3 1.0 CG A:PHE227 4.6 49.4 1.0 CB A:PHE227 4.6 55.5 1.0 CB A:VAL106 4.7 27.2 1.0 CG A:PRO236 4.7 43.2 1.0 CG A:PRO225 4.8 46.6 1.0 CG1 A:VAL106 4.9 28.6 1.0 CB A:PRO225 4.9 39.7 1.0

J.Ren, R.M.Esnouf, A.L.Hopkins, J.Warren, J.Balzarini, D.I.Stuart, D.K.Stammers. Crystal Structures of Hiv-1 Reverse Transcriptase in Complex with Carboxanilide Derivatives. Biochemistry V. 37 14394 1998.
ISSN: ISSN 0006-2960
PubMed: 9772165
DOI: 10.1021/BI981309M