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Atomistry » Chlorine » PDB 1swy-1tgg » 1ta6 » |
Chlorine in PDB 1ta6: Crystal Structure of Thrombin in Complex with Compound 14BEnzymatic activity of Crystal Structure of Thrombin in Complex with Compound 14B
All present enzymatic activity of Crystal Structure of Thrombin in Complex with Compound 14B:
3.4.21.5; Protein crystallography data
The structure of Crystal Structure of Thrombin in Complex with Compound 14B, PDB code: 1ta6
was solved by
T.J.Tucker,
S.F.Brady,
W.C.Lumma,
S.D.Lewis,
S.J.Gardel,
A.M.Naylor-Olsen,
Y.Yan,
J.T.Sisko,
K.J.Stauffer,
B.Y.Lucas,
J.J.Lynch,
J.J.Cook,
M.T.Stranieri,
M.A.Holahan,
E.A.Lyle,
E.P.Baskin,
I.-W.Chen,
K.B.Dancheck,
J.A.Krueger,
C.M.Cooper,
J.P.Vacca,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Crystal Structure of Thrombin in Complex with Compound 14B
(pdb code 1ta6). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of Thrombin in Complex with Compound 14B, PDB code: 1ta6: Chlorine binding site 1 out of 1 in 1ta6Go back to Chlorine Binding Sites List in 1ta6
Chlorine binding site 1 out
of 1 in the Crystal Structure of Thrombin in Complex with Compound 14B
Mono view Stereo pair view
Reference:
T.J.Tucker,
S.F.Brady,
W.C.Lumma,
S.D.Lewis,
S.J.Gardel,
A.M.Naylor-Olsen,
Y.Yan,
J.T.Sisko,
K.J.Stauffer,
B.Y.Lucas,
J.J.Lynch,
J.J.Cook,
M.T.Stranieri,
M.A.Holahan,
E.A.Lyle,
E.P.Baskin,
I.-W.Chen,
K.B.Dancheck,
J.A.Krueger,
C.M.Cooper,
J.P.Vacca.
Design and Synthesis of A Series of Potent and Orally Bioavailable Noncovalent Thrombin Inhibitors That Utilize Nonbasic Groups in the P1 Position J.Med.Chem. V. 41 3210 1998.
Page generated: Sat Dec 12 08:49:50 2020
ISSN: ISSN 0022-2623 PubMed: 9703466 DOI: 10.1021/JM9801713 |
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