Chlorine in PDB 1uj4: Crystal Structure of Thermus Thermophilus Ribose-5-Phosphate Isomerase

All present enzymatic activity of Crystal Structure of Thermus Thermophilus Ribose-5-Phosphate Isomerase:
5.3.1.6;

The structure of Crystal Structure of Thermus Thermophilus Ribose-5-Phosphate Isomerase, PDB code: 1uj4 was solved by K.Hamada, H.Ago, M.Sugahara, Y.Nodake, S.Kuramitsu, S.Yokoyama, M.Miyano, Riken Structural Genomics/Proteomics Initiative (Rsgi), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	43.86 / 1.80
Space group	C 2 2 21
Cell size a, b, c (Å), α, β, γ (°)	62.101, 61.965, 131.342, 90.00, 90.00, 90.00
R / Rfree (%)	19.2 / 21.5

The binding sites of Chlorine atom in the Crystal Structure of Thermus Thermophilus Ribose-5-Phosphate Isomerase (pdb code 1uj4). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 3 binding sites of Chlorine where determined in the Crystal Structure of Thermus Thermophilus Ribose-5-Phosphate Isomerase, PDB code: 1uj4:
Jump to Chlorine binding site number: 1; 2; 3;

Chlorine binding site 1 out of 3 in the Crystal Structure of Thermus Thermophilus Ribose-5-Phosphate Isomerase


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Thermus Thermophilus Ribose-5-Phosphate Isomerase within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl300 b:8.9 occ:1.00 O A:HOH1024 3.1 12.4 1.0 O A:HOH1013 3.2 3.9 1.0 NH2 A:ARG107 3.5 6.8 1.0 CA A:GLY173 4.0 7.7 1.0 NE A:ARG107 4.3 5.4 1.0 CZ A:ARG107 4.3 6.2 1.0 O A:GLY173 4.8 7.1 1.0 N A:GLY173 4.8 6.9 1.0 O A:ASP172 4.9 6.4 1.0 C A:GLY173 4.9 6.4 1.0

Chlorine binding site 2 out of 3 in the Crystal Structure of Thermus Thermophilus Ribose-5-Phosphate Isomerase


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of Thermus Thermophilus Ribose-5-Phosphate Isomerase within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl301 b:13.2 occ:1.00 OE2 A:GLU108 3.0 12.4 1.0 O A:HOH1222 3.1 34.5 1.0 O A:HOH1046 3.3 11.9 1.0 N A:GLY102 3.3 11.4 1.0 N A:ALA104 3.3 7.3 1.0 CA A:GLY102 3.4 11.3 1.0 N A:GLY103 3.5 10.3 1.0 C A:GLY102 3.6 12.3 1.0 CA A:GLY100 3.6 8.8 1.0 CD A:GLU108 3.7 10.9 1.0 OE1 A:GLU108 3.7 11.0 1.0 C A:GLY100 3.8 10.2 1.0 N A:GLY100 3.8 7.1 1.0 CA A:ALA104 4.0 6.0 1.0 CB A:ALA104 4.0 7.4 1.0 C A:ALA104 4.1 5.9 1.0 O A:GLY100 4.2 10.5 1.0 N A:MSE101 4.2 10.8 1.0 N A:LEU105 4.2 4.4 1.0 C A:GLY103 4.3 8.0 1.0 O A:GLY102 4.4 13.3 1.0 CA A:GLY103 4.4 9.5 1.0 C A:MSE101 4.5 12.9 1.0 O A:HOH1045 4.7 18.5 1.0 O A:HOH1149 4.7 40.1 1.0 O A:ALA104 4.8 5.3 1.0 O A:THR30 4.8 8.4 1.0 CG2 A:THR30 4.8 6.2 1.0 CB A:THR30 4.8 6.6 1.0

Chlorine binding site 3 out of 3 in the Crystal Structure of Thermus Thermophilus Ribose-5-Phosphate Isomerase


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Crystal Structure of Thermus Thermophilus Ribose-5-Phosphate Isomerase within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl302 b:21.6 occ:1.00 O A:HOH1177 3.0 29.1 1.0 N A:GLY144 3.1 6.1 1.0 CA A:GLY144 3.5 6.1 1.0 CD1 A:PHE143 4.2 8.4 1.0 CE1 A:PHE143 4.2 8.3 1.0 C A:PHE143 4.2 6.5 1.0 NH1 A:ARG146 4.4 19.0 1.0 CA A:PHE143 4.5 6.3 1.0 C A:GLY144 4.6 7.4 1.0 CG A:PHE143 4.6 8.2 1.0 CZ A:PHE143 4.6 8.4 1.0 N A:TYR145 4.8 7.3 1.0 O A:HOH1084 4.8 36.3 1.0

K.Hamada, H.Ago, M.Sugahara, Y.Nodake, S.Kuramitsu, M.Miyano. Oxyanion Hole-Stabilized Stereospecific Isomerization in Ribose-5-Phosphate Isomerase (Rpi) J.Biol.Chem. V. 278 49183 2003.
ISSN: ISSN 0021-9258
PubMed: 13679361
DOI: 10.1074/JBC.M309272200