Chlorine in PDB 1uwb: Tyr 181 Cys Hiv-1 Rt/8-Cl Tibo

All present enzymatic activity of Tyr 181 Cys Hiv-1 Rt/8-Cl Tibo:
2.7.7.49;

The structure of Tyr 181 Cys Hiv-1 Rt/8-Cl Tibo, PDB code: 1uwb was solved by K.Das, J.Ding, Y.Hsiou, E.Arnold, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	N/A / 3.20
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	225.700, 69.200, 104.900, 90.00, 106.60, 90.00
R / Rfree (%)	27.4 / 36

The binding sites of Chlorine atom in the Tyr 181 Cys Hiv-1 Rt/8-Cl Tibo (pdb code 1uwb). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Tyr 181 Cys Hiv-1 Rt/8-Cl Tibo, PDB code: 1uwb:

Chlorine binding site 1 out of 1 in the Tyr 181 Cys Hiv-1 Rt/8-Cl Tibo


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Tyr 181 Cys Hiv-1 Rt/8-Cl Tibo within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl559 b:67.9 occ:1.00 CL8 A:TBO559 0.0 67.9 1.0 C8 A:TBO559 1.7 67.4 1.0 C9 A:TBO559 2.7 67.6 1.0 C7A A:TBO559 2.8 67.7 1.0 C7 A:TBO559 3.1 66.5 1.0 CD2 A:TYR188 3.5 66.0 1.0 CE2 A:TYR188 3.6 67.2 1.0 CD2 A:PHE227 3.7 93.7 1.0 CG1 A:VAL106 3.9 57.9 1.0 C3A A:TBO559 4.0 68.7 1.0 C10 A:TBO559 4.1 68.8 1.0 CE2 A:PHE227 4.1 96.1 1.0 N6 A:TBO559 4.2 65.5 1.0 CB A:LEU234 4.4 69.7 1.0 C13 A:TBO559 4.4 63.6 1.0 CG A:PHE227 4.4 91.0 1.0 C12 A:TBO559 4.5 65.5 1.0 C1A A:TBO559 4.6 69.1 1.0 CG A:TYR188 4.8 65.2 1.0 CB A:VAL106 4.8 58.6 1.0 CB A:PHE227 4.8 87.0 1.0 CD2 A:LEU234 4.9 71.8 1.0 CZ A:TYR188 4.9 68.4 1.0 C14 A:TBO559 4.9 61.5 1.0

K.Das, J.Ding, Y.Hsiou, A.D.Clark Jr., H.Moereels, L.Koymans, K.Andries, R.Pauwels, P.A.Janssen, P.L.Boyer, P.Clark, R.H.Smith Jr., M.B.Kroeger Smith, C.J.Michejda, S.H.Hughes, E.Arnold. Crystal Structures of 8-Cl and 9-Cl Tibo Complexed with Wild-Type Hiv-1 Rt and 8-Cl Tibo Complexed with the TYR181CYS Hiv-1 Rt Drug-Resistant Mutant. J.Mol.Biol. V. 264 1085 1996.
ISSN: ISSN 0022-2836
PubMed: 9000632
DOI: 10.1006/JMBI.1996.0698