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Atomistry » Chlorine » PDB 1vq5-1wbo » 1wbn | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Chlorine » PDB 1vq5-1wbo » 1wbn » |
Chlorine in PDB 1wbn: Fragment Based P38 InhibitorsEnzymatic activity of Fragment Based P38 Inhibitors
All present enzymatic activity of Fragment Based P38 Inhibitors:
2.7.1.37; Protein crystallography data
The structure of Fragment Based P38 Inhibitors, PDB code: 1wbn
was solved by
A.Cleasby,
L.A.Devine,
A.L.Gill,
H.Jhoti,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Fragment Based P38 Inhibitors
(pdb code 1wbn). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Fragment Based P38 Inhibitors, PDB code: 1wbn: Chlorine binding site 1 out of 1 in 1wbnGo back to![]() ![]()
Chlorine binding site 1 out
of 1 in the Fragment Based P38 Inhibitors
![]() Mono view ![]() Stereo pair view
Reference:
A.L.Gill,
M.Frederickson,
A.Cleasby,
S.J.Woodhead,
M.G.Carr,
A.J.Woodhead,
M.T.Walker,
M.S.Congreve,
L.A.Devine,
D.Tisi,
M.O'reilly,
L.C.Seavers,
D.J.Davis,
J.Curry,
R.Anthony,
A.Padova,
C.W.Murray,
R.A.Carr,
H.Jhoti.
Identification of Novel P38ALPHA Map Kinase Inhibitors Using Fragment-Based Lead Generation. J.Med.Chem. V. 48 414 2005.
Page generated: Thu Jul 10 20:15:55 2025
ISSN: ISSN 0022-2623 PubMed: 15658855 DOI: 10.1021/JM049575N |
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