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Atomistry » Chlorine » PDB 1xkk-1y6p » 1xmu | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Chlorine » PDB 1xkk-1y6p » 1xmu » |
Chlorine in PDB 1xmu: Catalytic Domain of Human Phosphodiesterase 4B in Complex with RoflumilastEnzymatic activity of Catalytic Domain of Human Phosphodiesterase 4B in Complex with Roflumilast
All present enzymatic activity of Catalytic Domain of Human Phosphodiesterase 4B in Complex with Roflumilast:
3.1.4.17; Protein crystallography data
The structure of Catalytic Domain of Human Phosphodiesterase 4B in Complex with Roflumilast, PDB code: 1xmu
was solved by
G.L.Card,
B.P.England,
Y.Suzuki,
D.Fong,
B.Powell,
B.Lee,
C.Luu,
M.Tabrizizad,
S.Gillette,
P.N.Ibrahim,
D.R.Artis,
G.Bollag,
M.V.Milburn,
S.-H.Kim,
J.Schlessinger,
K.Y.J.Zhang,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 1xmu:
The structure of Catalytic Domain of Human Phosphodiesterase 4B in Complex with Roflumilast also contains other interesting chemical elements:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Catalytic Domain of Human Phosphodiesterase 4B in Complex with Roflumilast
(pdb code 1xmu). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total 4 binding sites of Chlorine where determined in the Catalytic Domain of Human Phosphodiesterase 4B in Complex with Roflumilast, PDB code: 1xmu: Jump to Chlorine binding site number: 1; 2; 3; 4; Chlorine binding site 1 out of 4 in 1xmuGo back to Chlorine Binding Sites List in 1xmu
Chlorine binding site 1 out
of 4 in the Catalytic Domain of Human Phosphodiesterase 4B in Complex with Roflumilast
Mono view Stereo pair view
Chlorine binding site 2 out of 4 in 1xmuGo back to Chlorine Binding Sites List in 1xmu
Chlorine binding site 2 out
of 4 in the Catalytic Domain of Human Phosphodiesterase 4B in Complex with Roflumilast
Mono view Stereo pair view
Chlorine binding site 3 out of 4 in 1xmuGo back to Chlorine Binding Sites List in 1xmu
Chlorine binding site 3 out
of 4 in the Catalytic Domain of Human Phosphodiesterase 4B in Complex with Roflumilast
Mono view Stereo pair view
Chlorine binding site 4 out of 4 in 1xmuGo back to Chlorine Binding Sites List in 1xmu
Chlorine binding site 4 out
of 4 in the Catalytic Domain of Human Phosphodiesterase 4B in Complex with Roflumilast
Mono view Stereo pair view
Reference:
G.L.Card,
B.P.England,
Y.Suzuki,
D.Fong,
B.Powell,
B.Lee,
C.Luu,
M.Tabrizizad,
S.Gillette,
P.N.Ibrahim,
D.R.Artis,
G.Bollag,
M.V.Milburn,
S.-H.Kim,
J.Schlessinger,
K.Y.J.Zhang.
Structural Basis For the Activity of Drugs That Inhibit Phosphodiesterases. Structure V. 12 2233 2004.
Page generated: Sat Dec 12 08:54:49 2020
ISSN: ISSN 0969-2126 PubMed: 15576036 DOI: 10.1016/J.STR.2004.10.004 |
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