Chlorine in PDB 1y6p: Crystal Structure of Disulfide Engineered Porcine Pancratic Phospholipase A2 to Group-X Isozyme

All present enzymatic activity of Crystal Structure of Disulfide Engineered Porcine Pancratic Phospholipase A2 to Group-X Isozyme:
3.1.1.4;

The structure of Crystal Structure of Disulfide Engineered Porcine Pancratic Phospholipase A2 to Group-X Isozyme, PDB code: 1y6p was solved by B.Z.Yu, Y.H.Pan, M.J.W.Jassen, B.J.Bahnson, M.K.Jain, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	19.80 / 2.25
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	34.988, 88.383, 38.560, 90.00, 105.65, 90.00
R / Rfree (%)	18.8 / 26.1

The structure of Crystal Structure of Disulfide Engineered Porcine Pancratic Phospholipase A2 to Group-X Isozyme also contains other interesting chemical elements:

Calcium

(Ca)

3 atoms

The binding sites of Chlorine atom in the Crystal Structure of Disulfide Engineered Porcine Pancratic Phospholipase A2 to Group-X Isozyme (pdb code 1y6p). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Crystal Structure of Disulfide Engineered Porcine Pancratic Phospholipase A2 to Group-X Isozyme, PDB code: 1y6p:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Crystal Structure of Disulfide Engineered Porcine Pancratic Phospholipase A2 to Group-X Isozyme


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Disulfide Engineered Porcine Pancratic Phospholipase A2 to Group-X Isozyme within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl220 b:23.1 occ:1.00 NH1 A:ARG53 3.2 26.2 1.0 NE A:ARG53 3.4 22.8 1.0 CZ A:ARG53 3.8 23.8 1.0 CD A:ARG53 4.6 20.9 1.0

Chlorine binding site 2 out of 2 in the Crystal Structure of Disulfide Engineered Porcine Pancratic Phospholipase A2 to Group-X Isozyme


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of Disulfide Engineered Porcine Pancratic Phospholipase A2 to Group-X Isozyme within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl221 b:40.5 occ:1.00 CG B:PRO110 3.1 18.1 1.0 O B:HOH302 3.4 15.2 1.0 N B:GLU40 4.0 10.5 1.0 CD B:PRO110 4.0 15.8 1.0 ND2 B:ASN112 4.0 19.8 1.0 CB B:ASP39 4.1 12.0 1.0 CB B:GLU40 4.2 13.3 1.0 CB B:PRO110 4.4 16.0 1.0 CA B:GLU40 4.7 11.4 1.0 CA B:ASP39 4.8 11.0 1.0 C B:ASP39 4.9 10.9 1.0 OE1 B:GLU40 5.0 20.4 1.0 CG B:ASP39 5.0 14.0 1.0

B.Z.Yu, Y.H.Pan, M.J.W.Janssen, B.J.Bahnson, M.K.Jain. Kinetic and Structural Properties of Disulfide Engineered Phospholipase A(2): Insight Into the Role of Disulfide Bonding Patterns. Biochemistry V. 44 3369 2005.
ISSN: ISSN 0006-2960
PubMed: 15736947
DOI: 10.1021/BI0482147