Chlorine in PDB 1ymk: Crystal Structure of the CDC25B Phosphatase Catalytic Domain in the Apo Form

All present enzymatic activity of Crystal Structure of the CDC25B Phosphatase Catalytic Domain in the Apo Form:
3.1.3.48;

The structure of Crystal Structure of the CDC25B Phosphatase Catalytic Domain in the Apo Form, PDB code: 1ymk was solved by G.K.Buhrman, B.Parker, J.Sohn, J.Rudolph, C.Mattos, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	29.77 / 1.70
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	50.237, 70.995, 73.905, 90.00, 90.00, 90.00
R / Rfree (%)	17.8 / 19.6

The binding sites of Chlorine atom in the Crystal Structure of the CDC25B Phosphatase Catalytic Domain in the Apo Form (pdb code 1ymk). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of the CDC25B Phosphatase Catalytic Domain in the Apo Form, PDB code: 1ymk:

Chlorine binding site 1 out of 1 in the Crystal Structure of the CDC25B Phosphatase Catalytic Domain in the Apo Form


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of the CDC25B Phosphatase Catalytic Domain in the Apo Form within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1001 b:12.9 occ:1.00 O A:HOH114 3.1 29.8 1.0 O A:HOH13 3.1 11.2 1.0 N A:ARG548 3.3 13.2 1.0 N A:GLU446 3.3 10.6 1.0 O A:HOH173 3.5 29.2 1.0 CA A:THR547 3.8 11.4 1.0 CD2 A:LEU445 3.9 9.7 1.0 CA A:LEU445 3.9 9.1 1.0 CB A:THR547 3.9 11.9 1.0 CB A:ARG548 4.0 18.3 1.0 CB A:GLU446 4.0 14.3 1.0 CG A:GLU446 4.0 19.1 1.0 C A:THR547 4.0 12.6 1.0 C A:LEU445 4.1 9.8 1.0 CA A:ARG548 4.2 14.1 1.0 CA A:GLU446 4.2 10.8 1.0 NH1 A:ARG447 4.3 10.2 1.0 CB A:LEU445 4.3 9.9 1.0 CG2 A:THR547 4.4 12.2 1.0 CD A:GLU446 4.5 21.9 1.0 O A:PRO444 4.7 10.2 1.0 CG A:LEU445 4.8 9.0 1.0 O A:HOH87 4.8 21.6 1.0 OE1 A:GLU446 4.9 22.6 1.0 OE2 A:GLU446 4.9 25.9 1.0 N A:ARG447 5.0 10.6 1.0 O A:HOH174 5.0 37.7 1.0

G.K.Buhrman, B.Parker, J.Sohn, J.Rudolph, C.Mattos. Structural Mechanism of Oxidative Regulation of the Phosphatase CDC25B Via An Intramolecular Disulfide Bond Biochemistry V. 44 5307 2005.
ISSN: ISSN 0006-2960
PubMed: 15807524
DOI: 10.1021/BI047449FS0006-2960(04)07449-5