Chlorine in PDB 1zco: Crystal Structure of Pyrococcus Furiosus 3-Deoxy-D-Arabino- Heptulosonate 7-Phosphate Synthase

All present enzymatic activity of Crystal Structure of Pyrococcus Furiosus 3-Deoxy-D-Arabino- Heptulosonate 7-Phosphate Synthase:
4.1.2.15;

The structure of Crystal Structure of Pyrococcus Furiosus 3-Deoxy-D-Arabino- Heptulosonate 7-Phosphate Synthase, PDB code: 1zco was solved by L.R.Schofield, B.F.Anderson, M.L.Patchett, G.E.Norris, G.B.Jameson, E.J.Parker, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	19.80 / 2.25
Space group	I 2 2 2
Cell size a, b, c (Å), α, β, γ (°)	87.231, 110.024, 144.350, 90.00, 90.00, 90.00
R / Rfree (%)	18.2 / 23.1

The structure of Crystal Structure of Pyrococcus Furiosus 3-Deoxy-D-Arabino- Heptulosonate 7-Phosphate Synthase also contains other interesting chemical elements:

Manganese

(Mn)

1 atom

The binding sites of Chlorine atom in the Crystal Structure of Pyrococcus Furiosus 3-Deoxy-D-Arabino- Heptulosonate 7-Phosphate Synthase (pdb code 1zco). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Crystal Structure of Pyrococcus Furiosus 3-Deoxy-D-Arabino- Heptulosonate 7-Phosphate Synthase, PDB code: 1zco:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Crystal Structure of Pyrococcus Furiosus 3-Deoxy-D-Arabino- Heptulosonate 7-Phosphate Synthase


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Pyrococcus Furiosus 3-Deoxy-D-Arabino- Heptulosonate 7-Phosphate Synthase within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl902 b:32.6 occ:0.50 O1P A:PEP901 2.3 28.9 0.5 NH1 A:ARG115 3.2 49.8 1.0 N A:ARG115 3.3 27.9 1.0 P A:PEP901 3.3 35.6 0.5 N A:ALA114 3.4 26.4 1.0 O3P A:PEP901 3.4 26.6 0.5 O A:HOH904 3.5 24.9 0.5 O2 A:PEP901 3.5 33.7 0.5 CB A:ARG115 3.7 28.1 1.0 CD A:ARG115 3.7 36.0 1.0 CG A:ARG115 3.8 31.8 1.0 CG A:PRO61 3.9 49.8 1.0 CB A:ALA114 3.9 23.0 1.0 C A:GLY113 4.0 29.3 1.0 CA A:ALA114 4.0 26.0 1.0 CA A:ARG115 4.1 28.7 1.0 CA A:GLY113 4.1 30.9 1.0 C A:ALA114 4.1 27.5 1.0 CZ A:ARG115 4.3 49.9 1.0 OE1 A:GLU93 4.3 49.0 1.0 CB A:PRO61 4.4 49.5 1.0 NE A:ARG115 4.4 45.2 1.0 OE2 A:GLU93 4.6 50.4 1.0 O2P A:PEP901 4.6 20.9 0.5 O A:GLY113 4.9 30.0 1.0 CD A:GLU93 4.9 41.1 1.0 C2 A:PEP901 4.9 34.0 0.5

Chlorine binding site 2 out of 2 in the Crystal Structure of Pyrococcus Furiosus 3-Deoxy-D-Arabino- Heptulosonate 7-Phosphate Synthase


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of Pyrococcus Furiosus 3-Deoxy-D-Arabino- Heptulosonate 7-Phosphate Synthase within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl1902 b:36.6 occ:0.50 O1P B:PEP1901 3.0 37.6 0.5 N B:ALA114 3.2 25.5 1.0 N B:ARG115 3.3 27.7 1.0 NH1 B:ARG115 3.3 52.0 1.0 O3P B:PEP1901 3.4 31.8 0.5 O2 B:PEP1901 3.4 34.3 0.5 P B:PEP1901 3.5 38.7 0.5 CA B:GLY113 3.7 28.4 1.0 C B:GLY113 3.7 26.1 1.0 CB B:ARG115 3.7 29.1 1.0 CG B:ARG115 3.9 31.0 1.0 CA B:ALA114 4.0 26.9 1.0 CD B:ARG115 4.0 38.1 1.0 O B:HOH1904 4.0 25.5 0.5 CB B:ALA114 4.1 23.9 1.0 OE1 B:GLU93 4.1 40.8 1.0 CG B:PRO61 4.1 45.7 0.5 CA B:ARG115 4.1 28.7 1.0 C B:ALA114 4.1 27.1 1.0 CZ B:ARG115 4.4 50.9 1.0 O B:HOH2015 4.5 43.3 1.0 OE2 B:GLU93 4.5 49.2 1.0 O B:GLY113 4.5 23.3 1.0 C2 B:PEP1901 4.6 34.2 0.5 C3 B:PEP1901 4.6 34.4 0.5 CB B:PRO61 4.7 45.8 0.5 NE B:ARG115 4.7 42.5 1.0 CD B:GLU93 4.8 37.3 1.0 N B:ASN116 4.9 28.5 1.0 N B:GLY113 4.9 29.6 1.0 O2P B:PEP1901 5.0 32.1 0.5

L.R.Schofield, B.F.Anderson, M.L.Patchett, G.E.Norris, G.B.Jameson, E.J.Parker. Substrate Ambiguity and Crystal Structure of Pyrococcus Furiosus 3-Deoxy-D-Arabino-Heptulosonate-7-Phosphate Synthase: An Ancestral 3-Deoxyald-2-Ulosonate-Phosphate Synthase?(,) Biochemistry V. 44 11950 2005.
ISSN: ISSN 0006-2960
PubMed: 16142893
DOI: 10.1021/BI050577Z