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Atomistry » Chlorine » PDB 1zch-1zoh » 1zgv » |
Chlorine in PDB 1zgv: Thrombin in Complex with An Oxazolopyridine Inhibitor 2Enzymatic activity of Thrombin in Complex with An Oxazolopyridine Inhibitor 2
All present enzymatic activity of Thrombin in Complex with An Oxazolopyridine Inhibitor 2:
3.4.21.5; Protein crystallography data
The structure of Thrombin in Complex with An Oxazolopyridine Inhibitor 2, PDB code: 1zgv
was solved by
J.Z.Deng,
D.R.Mcmasters,
P.M.Rabbat,
P.D.Williams,
C.A.Coburn,
Y.Yan,
L.C.Kuo,
S.D.Lewis,
B.J.Lucas,
J.A.Krueger,
B.Strulovici,
J.P.Vacca,
T.A.Lyle,
C.S.Burgey,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Thrombin in Complex with An Oxazolopyridine Inhibitor 2
(pdb code 1zgv). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Thrombin in Complex with An Oxazolopyridine Inhibitor 2, PDB code: 1zgv: Chlorine binding site 1 out of 1 in 1zgvGo back to Chlorine Binding Sites List in 1zgv
Chlorine binding site 1 out
of 1 in the Thrombin in Complex with An Oxazolopyridine Inhibitor 2
Mono view Stereo pair view
Reference:
J.Z.Deng,
D.R.Mcmasters,
P.M.Rabbat,
P.D.Williams,
C.A.Coburn,
Y.Yan,
L.C.Kuo,
S.D.Lewis,
B.J.Lucas,
J.A.Krueger,
B.Strulovici,
J.P.Vacca,
T.A.Lyle,
C.S.Burgey.
Development of An Oxazolopyridine Series of Dual Thrombin/Factor Xa Inhibitors Via Structure-Guided Lead Optimization. Bioorg.Med.Chem.Lett. V. 15 4411 2005.
Page generated: Sat Dec 12 08:56:57 2020
ISSN: ISSN 0960-894X PubMed: 16137886 DOI: 10.1016/J.BMCL.2005.07.022 |
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